Huang, Xu-Feng

Overview

Distinguished Professor Xu-Feng Huang’s (MBBS, PhD, DSc) extensive research track record in neuropharmacology, metabolism, and molecular nutrition has led to significant impacts in combatting obesity induced by diet and antipsychotic drugs. His contributions, supported by major Australian competitive funding, include identifying: (a) central leptin resistance in the late stages of obesity resulting in a different treatment strategy, (b) the satiety enhancer oat β-glucan for combating obesity, which was incorporated into the NHMRC Australian Dietary Guidelines 2011, Food Standards ANZ 2015, and used by Uncle Toby’s for product development, (c) the site of the antipsychotic drug responsible for obesity, leading to new drug developments, and (d) that mental illness patients with diabetes have worse cognitive functioning, requiring combination therapy. He has published 253 research articles, with over 13,200 citations and supervised 26 PhD students. He is Director of Translational Neuroscience Centre at UOW and Leader of Mental Health theme in IHMRI 2019.

Career Summary: After the completion of a PhD at the University of New South Wales Australia (UNSW), Prof Huang received 3 years of postdoctoral training in the Schools of Psychology and Pathology at UNSW. He then joined the University of Wollongong (UOW) as a Lecturer in October, 1995. He was awarded Doctor of Science (DSc) in 2012. He initiated and established the Center for Translational Neuroscience at UOW studying the central control of energy balance associated with obesity and neuropharmacology of antipsychotic drugs since 1999. He joined the Illawarra Health and Medical Research Institute (IHMRI) in 2010 and was subsequently appointed as Foundation Scientific Director of the Metabolic Theme from September 2010 to June 2012. He was Acting Executive Director of IHMRI from Nov 2012 to June 2013 and Deputy Executive Director (Scientific) from July 2011 to Jan 2016 and Theme Leader of the Mental Health and Ageing Brain from 2017 to 2019. He received the Vice-Chancellor’s Research Excellence Award for Senior Researcher of the Year 2014. From 2017 to now, he is Theme Leader for Mental Health and Ageing Brain theme in IHMRI.

Disciplinary expertise: He has broad knowledge from cell and animal based research to clinical research and biostatistics. His expertise is in neuropharmacology, metabolism, molecular nutrition, and clinical psychiatric studies. His research investigates the mechanisms of neurotransmission and intracellular signal transduction using cell and rodent models, computational modelling, and clinical studies. His publications reflect his expertise in neuropharmacology, the mechanism of antipsychotic drug action and molecular nutrition for obesity, metabolic disorders and schizophrenia.

Top Publications

Year	Title
2009	The Rhesus Monkey Brain in Stereotaxic Coordinates
2019	Aripiprazole and haloperidol protect neurite lesions via reducing excessive D2R-DISC1 complex formation Published in Progress in Neuro-Psychopharmacology and Biological Psychiatry
2018	Dietary Galacto-Oligosaccharides and Resistant Starch Protect Against Altered CB1 and 5-HT1A and 2A Receptor Densities in Rat Brain: Implications for Preventing Cognitive and Appetite Dysfunction During a High-Fat Diet Published in Molecular Nutrition and Food Research
2019	Effects of antipsychotic drugs on neurites relevant to schizophrenia treatment Published in Medicinal Research Reviews
2018	Electrical Stimulation with a Conductive Polymer Promotes Neurite Outgrowth and Synaptogenesis in Primary Cortical Neurons in 3D Published in Scientific Reports
2015	Gender differences in cognitive deficits in schizophrenia with and without diabetes Published in Comprehensive Psychiatry
2017	Gender differences measured by the MATRICS consensus cognitive battery in chronic schizophrenia patients Published in Scientific Reports
2017	Molecular mechanisms of antipsychotic drug-induced diabetes Published in Frontiers in Neuroscience
2019	Patients with drug-naive bipolar disorder in remission after 8 weeks of treatment had decreased serum uric acid concentrations Published in Frontiers in Psychiatry
2018	Serum NCAM levels and cognitive deficits in first episode schizophrenia patients versus health controls Published in Schizophrenia Research

Research Areas

Research Overview

Publications: He has published 253 full research papers, 3 books, 9 book chapters and attracted more than 12,999 citations (Google Scholar 2020). He has an h-index of 57, with 24 publications having over 100 cites – He received an average 912 cites per year over the last 10 years, and 1,116 cites per year for the last 5 years (GS). In the last 10 years, he published 162 primary research papers, of which 94 are in the top 10% of journals (SJR), and 22 are in the top 10% for number of citations, for his field, worldwide (SciVal)–reflecting the impact his research program has had on the field.

Collaborations: He has an extensive collaboration network with world leading research laboratories both nationally and internationally. This enables him to access advanced knowledge, skills, equipment, and databases, to receive international and industry research funding, and to attract highly talented HDR students and postdoctoral research fellows.

Supervision and mentoring of Postdoctoral Fellows and Postgraduate Students: He has successfully mentored postgraduate completions comprising 12 PhD and 4 Masters students, as well as 4 Honours students in the last 5 years. Over his research career, He has mentored 14 postdoctoral fellows, 8 international visiting fellows and 6 research assistants. He received the University of Wollongong Vice Chancellor’s Excellence in Research Supervision Award in 2010.

Contribution to NHMRC, ARC and Peer review involvement: He has been an external assessor reviewing various project grants including for NHMRC from 1997 to present, IHMRI from 2012 to 2015, Schizophrenia Research Institute from 2010 to 2015, Medical Research Commercialisation Fund from 2012 to 2013, ARC Future Fellowship in 2012 and Diabetes Australia 2011-2013. He is Editorial Board Member for Frontier Neuroscience, International J of Obesity, Basic Sciences of Medicine, and a reviewer for more than 20 leading international referred journals.

Geographic Focus

Australia Country

Available as Research Supervisor

Available for Collaborative Projects

Selected Publications

Journal Article

Year	Title
2021	Cannabidiol regulates CB1-pSTAT3 signaling for neurite outgrowth, prolongs lifespan, and improves health span in Caenorhabditis elegans of Aß pathology models Published In FASEB Journal
2021	Defect-Rich La2O3Nanoparticles with Antioxidant Activity for Human Keratinocytes Published In ACS Applied Nano Materials
2021	Olanzapine Induces Inflammation and Immune Response via Activating ER Stress in the Rat Prefrontal Cortex Published In Current Medical Science
2021	Olanzapine-Induced Activation of Hypothalamic Astrocytes and Toll-Like Receptor-4 Signaling via Endoplasmic Reticulum Stress Were Related to Olanzapine-Induced Weight Gain Published In Frontiers in Neuroscience
2021	The Role of Butyric Acid in Treatment Response in Drug-Naïve First Episode Schizophrenia. Published In Front Psychiatry
2021	The kynurenine pathway in major depression: What we know and where to next Published In Neuroscience and Biobehavioral Reviews
2021	Theranostic two-dimensional superparamagnetic maghemite quantum structures for ROS-mediated cancer therapy Published In Journal of Materials Chemistry B
2021	ß-Glucan from Lentinula edodes prevents cognitive impairments in high-fat diet-induced obese mice: involvement of colon-brain axis Published In Journal of Translational Medicine
2020	A synergistic effect between family intervention and rTMS improves cognitive and negative symptoms in schizophrenia: A randomized controlled trial Published In Journal of Psychiatric Research
2020	Bipolar electroactive conducting polymers for wireless cell stimulation Published In Applied Materials Today
2020	Curdlan Prevents the Cognitive Deficits Induced by a High-Fat Diet in Mice via the Gut-Brain Axis Published In Frontiers in Neuroscience
2020	DHA reduces hypothalamic inflammation and improves central leptin signaling in mice Published In Life Sciences
2020	Data on the bipolar electroactive conducting polymers for wireless cell stimulation Published In Data in Brief
2020	Decreased serum NCAM is positively correlated with hippocampal volumes and negatively correlated with positive symptoms in first-episode schizophrenia patients Published In Journal of Psychiatric Research
2020	Insulin Resistance and Oxidative Stress: In Relation to Cognitive Function and Psychopathology in Drug-Naïve, First-Episode Drug-Free Schizophrenia Published In Frontiers in Psychiatry
2020	Investigation of ROS scavenging properties and in vitro cytotoxicity of oxygen-deficient La2O3-x nanostructure synthesized by spray pyrolysis method Published In JOURNAL OF NANOSTRUCTURE IN CHEMISTRY
2020	N-acetylcysteine prevents olanzapine-induced oxidative stress in mHypoA-59 hypothalamic neurons Published In Scientific Reports
2020	Olanzapine increases AMPK-NPY orexigenic signaling by disrupting H1R-GHSR1a interaction in the hypothalamic neurons of mice Published In Psychoneuroendocrinology
2020	Prevention of Neurite Spine Loss Induced by Dopamine D2 Receptor Overactivation in Striatal Neurons Published In Frontiers in Neuroscience
2020	Risperidone stimulates food intake and induces body weight gain via the hypothalamic arcuate nucleus 5-HT2c receptor¿NPY pathway Published In CNS Neuroscience and Therapeutics
2020	Supplement of microbiota-accessible carbohydrates prevents neuroinflammation and cognitive decline by improving the gut microbiota-brain axis in diet-induced obese mice Published In Journal of Neuroinflammation
2020	ß-glucan attenuates cognitive impairment via the gut-brain axis in diet-induced obese mice Published In Microbiome
2019	Alterations to the microbiota–colon–brain axis in high-fat-diet-induced obese mice compared to diet-resistant mice Published In Journal of Nutritional Biochemistry
2019	An alternating least square based algorithm for predicting patient survivability Published In Communications in Computer and Information Science
2019	Aripiprazole and haloperidol protect neurite lesions via reducing excessive D2R-DISC1 complex formation Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2019	Cannabidiol improves behavioural and neurochemical deficits in adult female offspring of the maternal immune activation (poly I:C) model of neurodevelopmental disorders Published In Brain, Behavior, and Immunity
2019	Effect of cannabidiol on endocannabinoid, glutamatergic and GABAergic signalling markers in male offspring of a maternal immune activation (poly I:C) model relevant to schizophrenia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2019	Effects of antipsychotic drugs on neurites relevant to schizophrenia treatment Published In Medicinal Research Reviews
2019	Increased translocator protein (TSPO) binding throughout neurodevelopment in the perinatal phencyclidine rodent model of schizophrenia Published In Schizophrenia Research
2019	Nano-sunscreens – a double-edged sword in protecting consumers from harm: viewing Australian regulatory policies through the lenses of the European Union Published In Critical Reviews in Toxicology
2019	Olanzapine-induced endoplasmic reticulum stress and inflammation in the hypothalamus were inhibited by an ER stress inhibitor 4-phenylbutyrate Published In Psychoneuroendocrinology
2019	Patients with drug-naive bipolar disorder in remission after 8 weeks of treatment had decreased serum uric acid concentrations Published In Frontiers in Psychiatry
2019	Sensitivity of plasma cholecystokinin and peptide YY in obese and normal weight men Published In Malaysian Journal of Nutrition
2019	Tacrine-Hydrogen Sulfide Donor Hybrid Ameliorates Cognitive Impairment in the Aluminum Chloride Mouse Model of Alzheimer's Disease Published In ACS Chemical Neuroscience
2019	The gut microbiota promotes the pathogenesis of schizophrenia via multiple pathways Published In Biochemical and Biophysical Research Communications
2018	3D imaging of PSD-95 in the mouse brain using the advanced CUBIC method Published In Molecular Brain
2018	A postmortem analysis of NMDA ionotropic and group 1 metabotropic glutamate receptors in the nucleus accumbens in schizophrenia Published In Journal of Psychiatry and Neuroscience
2018	Association between hyperuricemia and metabolic syndrome in patients suffering from bipolar disorder Published In BMC Psychiatry
2018	Changes in metabolism and microbiota after 24-week risperidone treatment in drug naïve, normal weight patients with first episode schizophrenia Published In Schizophrenia Research
2018	Chronic Adolescent CDPPB Treatment Alters Short-Term, but not Long-Term, Glutamatergic Receptor Expression Published In Neurochemical Research
2018	Cold exposure promotes obesity and impairs glucose homeostasis in mice subjected to a highfat diet Published In Molecular Medicine Reports
2018	Commentary: GLYX-13 Ameliorates Schizophrenia-Like Phenotype Induced by MK-801 in Mice: Role of Hippocampal NR2B and DISC1 Published In Frontiers in Molecular Neuroscience
2018	Decreased 5‐HT2cR and GHSR1a interaction in antipsychotic drug‐induced obesity Published In Obesity Reviews
2018	Dietary Galacto-Oligosaccharides and Resistant Starch Protect Against Altered CB1 and 5-HT1A and 2A Receptor Densities in Rat Brain: Implications for Preventing Cognitive and Appetite Dysfunction During a High-Fat Diet Published In Molecular Nutrition and Food Research
2018	Disrupted sphingolipid metabolism following acute clozapine and olanzapine administration Published In British Journal of Biomedical Science
2018	Early antipsychotic treatment in juvenile rats elicits long-term alterations to the adult serotonin receptors Published In Neuropsychiatric Disease and Treatment
2018	Effect of multi-walled carbon nanotubes on the cross-linking density of the poly(glycerol sebacate) elastomeric nanocomposites Published In Journal of Colloid and Interface Science
2018	Effects of short- and long-term aripiprazole treatment on Group I mGluRs in the nucleus accumbens: Comparison with haloperidol Published In Psychiatry Research
2018	Electrical Stimulation with a Conductive Polymer Promotes Neurite Outgrowth and Synaptogenesis in Primary Cortical Neurons in 3D Published In Scientific Reports
2018	Epidemiology of birth defects based on surveillance data from 2011-2015 in Guangxi, China: comparison across five major ethnic groups Published In BMC PUBLIC HEALTH
2018	Galantamine improves cognition, hippocampal inflammation, and synaptic plasticity impairments induced by lipopolysaccharide in mice Published In Journal of Neuroinflammation
2018	Ginsenoside Rb1 improves leptin sensitivity in the prefrontal cortex in obese mice Published In CNS Neuroscience and Therapeutics
2018	Liraglutide prevents metabolic side-effects and improves recognition and working memory during antipsychotic treatment in rats Published In Journal of Psychopharmacology
2018	Microglia activation in the offspring of prenatal Poly I: C exposed rats: a PET imaging and immunohistochemistry study Published In General Psychiatry
2018	Obesity, altered oxidative stress, and clinical correlates in chronic schizophrenia patients Published In Translational Psychiatry
2018	Perinatal administration of phencyclidine alters expression of Lingo-1 signaling pathway proteins in the prefrontal cortex of juvenile and adult rats Published In Neuronal Signaling
2018	Propionate protects haloperidol-induced neurite lesions mediated by neuropeptide Y Published In Frontiers in Neuroscience
2018	RANKL reduces body weight and food intake via the modulation of hypothalamic NPY/CART expression Published In International Journal of Medical Sciences
2018	Serum NCAM levels and cognitive deficits in first episode schizophrenia patients versus health controls Published In Schizophrenia Research
2017	Alterations of ubiquitin related proteins in the pathology and development of schizophrenia: Evidence from human and animal studies Published In Journal of Psychiatric Research
2017	Association between DBH 19 bp insertion/deletion polymorphism and cognition in schizophrenia with and without tardive dyskinesia Published In Schizophrenia Research
2017	Cannabidiol rescues glutamatergic, memory and social interaction deficits following prenatal infection: a follow-up in female offspring Published In European Neuropsychopharmacology
2017	Correction: Prevalence and correlates of psychological distress among diabetes mellitus adults in the Jilin province in China: a cross-sectional study. Published In PeerJ
2017	Current views on neuropeptide Y and diabetes-related atherosclerosis Published In Diabetes and Vascular Disease Research
2017	Dietary teasaponin ameliorates alteration of gut microbiota and cognitive decline in diet-induced obese mice Published In Scientific Reports
2017	Electrical stimulation using conductive polymer polypyrrole counters reduced neurite outgrowth of primary prefrontal cortical neurons from NRG1-KO and DISC1-LI mice Published In Scientific Reports
2017	Gender differences measured by the MATRICS consensus cognitive battery in chronic schizophrenia patients Published In Scientific Reports
2017	Improved social interaction, recognition and working memory with cannabidiol treatment in a prenatal infection (poly I:C) rat model Published In Neuropsychopharmacology
2017	Intake of 7,8-dihydroxyflavone from pregnancy to weaning prevents cognitive deficits in adult offspring after maternal immune activation Published In European Archives of Psychiatry and Clinical Neuroscience: official organ of the German society for biological psychiatry
2017	Luteolin, a natural flavonoid, inhibits methylglyoxal induced apoptosis via the mTOR/4E-BP1 signaling pathway Published In Scientific Reports
2017	Molecular mechanisms of antipsychotic drug-induced diabetes Published In Frontiers in Neuroscience
2017	Prevalence and correlates of psychological distress among diabetes mellitus adults in the Jilin province in China: a cross-sectional study Published In PEERJ
2017	Prevalence and correlates of psychological distress among diabetes mellitus adults in the Jilin province in China: a cross-sectional study Published In PeerJ
2017	Probe Sensor Using Nanostructured Multi-Walled Carbon Nanotube Yarn for Selective and Sensitive Detection of Dopamine Published In Sensors
2017	Reduced serum levels of oestradiol and brain derived neurotrophic factor in both diabetic women and HFD-feeding female mice Published In Endocrine
2017	Tailoring the wettability and mechanical properties of electrospun poly(L-lactic acid)-poly(glycerol sebacate) core-shell membranes for biomedical applications Published In Journal of Colloid and Interface Science
2017	The central mechanism of risperidone-induced hyperprolactinemia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2017	Time-dependent changes and potential mechanisms of glucose-lipid metabolic disorders associated with chronic clozapine or olanzapine treatment in rats Published In Scientific Reports
2017	Time-dependent effects of olanzapine treatment on the expression of histidine decarboxylase, H1 and H3 receptor in the rat brain: The roles in olanzapine-induced obesity Published In Psychoneuroendocrinology
2016	A label-free and high-throughput separation of neuron and glial cells using an inertial microfluidic platform Published In Biomicrofluidics
2016	A splicing-regulatory polymorphism in DRD2 disrupts ZRANB2 binding, impairs cognitive functioning and increases risk for schizophrenia in six Han Chinese samples Published In Molecular Psychiatry
2016	Ameliorating antipsychotic-induced weight gain by betahistine: mechanisms and clinical implications Published In Pharmacological Research
2016	Aripiprazole and haloperidol activate GSK3β-dependent signalling pathway differentially in various brain regions of rats Published In International Journal of Molecular Sciences
2016	Aripiprazole increases the PKA signalling and expression of the GABA_A receptor and CREB1 in the nucleus accumbens of rats Published In Journal of Molecular Neuroscience
2016	Association between DβH5′ insertion/deletion polymorphism and cognition in patients with chronic schizophrenia Published In Journal of Clinical Psychiatry
2016	Bardoxolone methyl prevents high-fat diet-induced colon inflammation in mice Published In Journal of Histochemistry and Cytochemistry: imaging the spectrum of cell biology
2016	Bardoxolone methyl prevents obesity and hypothalamic dysfunction Published In Chemico-Biological Interactions
2016	Chlorogenic acid protects d-galactose-induced liver and kidney injury via antioxidation and anti-inflammation effects in mice Published In Pharmaceutical Biology
2016	Chronic administration of aripiprazole activates GSK3β-dependent signalling pathways, and up-regulates GABA_A receptor expression and CREB1 activity in rats Published In Scientific Reports
2016	Chronic rhein treatment improves recognition memory in high-fat diet-induced obese male mice Published In Journal of Nutritional Biochemistry
2016	Early antipsychotic treatment in childhood/adolescent period has long-term effects on depressive-like, anxiety-like and locomotor behaviours in adult rats Published In Journal of Psychopharmacology
2016	Early antipsychotic treatment in juvenile rats elicits long-term alterations to the dopamine neurotransmitter system Published In International Journal of Molecular Sciences
2016	Effect of a glucagon-like peptide 1 (GLP-1) receptor agonist, liraglutide, on cognition and body weight during antipsychotic treatment Published In International Journal of Neuropsychopharmacology
2016	Effect of cannabidiol on cognition in a maternal immune activation (poly IC) model of schizophrenia Published In International Journal of Neuropsychopharmacology
2016	Erratum to: MGluR2/3 agonist LY379268 rescues NMDA and GABAA receptor level deficits induced in a two-hit mouse model of schizophrenia Published In Psychopharmacology
2016	Intake of 7,8-dihydroxyflavone during juvenile and adolescent stages prevents onset of psychosis in adult offspring after maternal immune activation Published In Scientific Reports
2016	Interaction of BDNF with cytokines in chronic schizophrenia Published In Brain, Behavior, and Immunity
2016	Neurodevelopmental expression profile of dimeric and monomeric group 1 mGluRs: relevance to schizophrenia pathogenesis and treatment Published In Scientific Reports
2016	Olanzapine prevents the PCP-induced reduction in the neurite outgrowth of prefrontal cortical neurons via NRG1 Published In Scientific Reports
2016	PM336. Early Antipsychotic Treatment in Childhood/Adolescent Period has Long-term Effects on Dopamine Receptors of Adult Rat Brains Published In The International Journal of Neuropsychopharmacology
2016	PM439. Chronic effects of aripiprazole on the GSK3ß-dependent pathways, NMDA receptor and CREB1 in the rat brain Published In The International Journal of Neuropsychopharmacology
2016	PS146. Norbin: an emerging player in the pathophysiology and treatment of depression? Published In The International Journal of Neuropsychopharmacology
2016	Protective effect of the orientin on noise-induced cognitive impairments in mice Published In Behavioural Brain Research
2016	Reversal effect of simvastatin on the decrease in cannabinoid receptor 1 density in 6-hydroxydopamine lesioned rat brains Published In Life Sciences
2016	Selective binding modes and allosteric inhibitory effects of lupane triterpenes on protein tyrosine phosphatase 1B Published In Scientific Reports
2016	Smoking and serum lipid profiles in schizophrenia Published In Neuroscience Bulletin
2016	The Neurodevelopmental Profile of Group 1 Metabotropic Glutamate Receptors: Implications for Novel Therapeutics Published In International Journal of Neuropsychopharmacology
2016	Use of conducting polymers to facilitate neurite branching in schizophrenia-related neuronal development Published In Biomaterials Science
2016	mGluR2/3 agonist LY379268 rescues NMDA and GABAA receptor level deficits induced in a two-hit mouse model of schizophrenia Published In Psychopharmacology
2015	Alterations of mGluR5 and its endogenous regulators Norbin, Tamalin and Preso1 in schizophrenia: towards a model of mGluR5 dysregulation Published In Acta Neuropathologica
2015	Alterations of p75 neurotrophin receptor and Myelin transcription factor 1 in the hippocampus of perinatal phencyclidine treated rats Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2015	Altered IL-2, IL-6 and IL-8 serum levels in schizophrenia patients with tardive dyskinesia Published In Schizophrenia Research
2015	Arachidonic acid impairs hypothalamic leptin signaling and hepatic energy homeostasis in mice Published In Molecular and Cellular Endocrinology
2015	Bardoxolone methyl prevents fat deposition and inflammation in brown adipose tissue and enhances sympathetic activity in mice fed a high-fat diet Published In Nutrients
2015	Bardoxolone methyl prevents fat deposition and inflammation in the visceral fat of mice fed a high-fat diet Published In Chemico-Biological Interactions
2015	Bardoxolone methyl prevents high-fat diet-induced alterations in prefrontal cortex signalling molecules involved in recognition memory Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2015	Bardoxolone methyl prevents insulin resistance and the development of hepatic steatosis in mice fed a high-fat diet Published In Molecular and Cellular Endocrinology
2015	Bardoxolone methyl prevents mesenteric fat deposition and inflammation in high-fat diet mice Published In The Scientific World Journal
2015	Bardoxolone methyl prevents the development and progression of cardiac and renal pathophysiologies in mice fed a high-fat diet Published In Chemico-Biological Interactions
2015	Chronic betahistine co-treatment reverses olanzapine's effects on dopamine D2 but not 5-HT2A/2C bindings in rat brains Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2015	Cognitive differences in schizophrenia on long-term treatments with clozapine, risperidone and typical antipsychotics Published In International Clinical Psychopharmacology
2015	Differential effects of short- and long-term antipsychotic treatment on the expression of neuregulin-1 and ErbB4 receptors in the rat brain Published In Psychiatry Research
2015	Gender differences in cognitive deficits in schizophrenia with and without diabetes Published In Comprehensive Psychiatry
2015	Glucose disturbances in first-episode drug-naïve schizophrenia: relationship to psychopathology Published In Psychoneuroendocrinology
2015	High fat diet-induced obesity increases the formation of colon polyps induced by azoxymethane in mice Published In Annals of Translational Medicine
2015	Is B-type natriuretic peptide a risk factor for heart failure in patients treated with bardoxolone methyl? Published In Journal of Cardiac Failure
2015	Metabotropic glutamate receptor 5, and its trafficking molecules Norbin and Tamalin, are increased in the CA1 hippocampal region of subjects with schizophrenia Published In Schizophrenia Research
2015	NMDA receptor antagonism by phencyclidine reduces NWASP and WAVE1 protein expression and reduces levels of myelination markers in the prefrontal cortex of rats Published In Journal of Pharmaceutics & Pharmacology
2015	Neuregulin 1 expression and electrophysiological abnormalities in the Neuregulin 1 transmembrane domain heterozygous mutant mouse Published In PLoS One
2015	Neuregulin 1 prevents phencyclidine-induced behavioral impairments and disruptions to GABAergic signaling in mice Published In International Journal of Neuropsychopharmacology
2015	Orientin improves depression-like behavior and BDNF in chronic stressed mice Published In Molecular Nutrition and Food Research
2015	Palmitic acid induces central leptin resistance and impairs hepatic glucose and lipid metabolism in male mice Published In Journal of Nutritional Biochemistry
2015	Possible association between DBH 19 bp insertion/deletion polymorphism and clinical symptoms in schizophrenia with tardive dyskinesia Published In Journal of Neural Transmission
2015	Preimplantation exposure to Bisphenol A and Triclosan may lead to implantation failure in humans Published In BioMed Research International
2015	Teasaponin improves leptin sensitivity in the prefrontal cortex of obese mice Published In Molecular Nutrition and Food Research
2015	Unique effects of acute aripiprazole treatment on the dopamine D2 receptor downstream cAMP-PKA and Akt-GSK3β signalling pathways in rats Published In PLoS One
2014	A high-dose Shiitake mushroom increases hepatic accumulation of triacylglycerol in rats fed a high-fat diet: underlying mechanism Published In Nutrients
2014	Alterations of NMDA receptor binding in various brain regions among 6-hydroxydopamine-induced Parkinsonian rats Published In International Journal of Neuroscience
2014	Awareness, treatment, control of diabetes mellitus and the risk factors: survey results from Northeast China Published In PLoS One
2014	Betahistine ameliorates olanzapine-induced weight gain through modulation of histaminergic, NPY and AMPK pathways Published In Psychoneuroendocrinology
2014	Central inflammation and leptin resistance are attenuated by ginsenoside Rb1 treatment in obese mice fed a high-fat diet Published In PLoS One
2014	Comment on: Oleanolic acid co-administration alleviates ethanol-induced hepatic injury via Nrf-2 and ethanol-metabolizing modulation (sic) in rats Published In Chemico-Biological Interactions
2014	Different effects of Bifeprunox, Aripiprazole, and Haloperidol on body weight gain, food and water intake, and locomotor activity in rats Published In Pharmacology, Biochemistry and Behavior
2014	Dyslipidemia awareness, treatment, control and influence factors among adults in the Jilin province in China: a cross-sectional study Published In Lipids in Health and Disease
2014	Effects of olanzapine on the elevation of macrophage infiltration and pro-inflammatory cytokine expression in female rats Published In Journal of Psychopharmacology
2014	GluN2B protein deficits in the left, but not the right, hippocampus in schizophrenia Published In BMC Psychiatry
2014	Hypothalamic ghrelin signalling mediates olanzapine-induced hyperphagia and weight gain in female rats Published In International Journal of Neuropsychopharmacology
2014	Hypothalamic histamine H1 receptor-AMPK signaling time-dependently mediates olanzapine-induced hyperphagia and weight gain in female rats Published In Psychoneuroendocrinology
2014	Metabotropic glutamate receptor mGluR2/3 and mGluR5 binding in the anterior cingulate cortex in psychotic and nonpsychotic depression, bipolar disorder and schizophrenia: implications for novel mGluR-based therapeutics Published In Journal of Psychiatry and Neuroscience
2014	Novel implications of Lingo-1 and its signaling partners in schizophrenia Published In Translational Psychiatry
2014	Novel implications of lingo-1 signaling in the post-mortem schizophrenia brain Published In Biological Psychiatry
2014	Olanzapine reduced brown adipose tissue thermogenesis and locomotor activity in female rats Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2014	Olanzapine-activated AMPK signaling in the dorsal vagal complex is attenuated by histamine H1 receptor agonist in female rats Published In Endocrinology
2014	Poster #S173 METABOTROPIC GLUTAMATE RECEPTOR 5 DYSREGULATION IN SCHIZOPHRENIA Published In Schizophrenia Research
2014	Preventing olanzapine-induced weight gain using betahistine: a study in a rat model with chronic olanzapine treatment Published In PLoS One
2014	Simvastatin reverses the downregulation of M1/4 receptor binding in 6-hydroxydopamine-induced parkinsonian rats: the association with improvements in long-term memory Published In Neuroscience
2014	The differences of cognitive deficits in chronic schizophrenia on long-term treatment with typical and atypical antipsychotics Published In International Journal of Neuropsychopharmacology
2014	The endothelin pathway: a protective or detrimental target of bardoxolone methyl on cardiac function in patients with advanced chronic kidney disease? Published In American Journal of Nephrology
2014	The molecular mechanisms underpinning the therapeutic properties of oleanolic acid, its isomer and derivatives for type 2 diabetes and associated complications Published In Molecular Nutrition and Food Research
2013	A neuregulin 1 transmembrane domain mutation causes imbalanced glutamatergic and dopaminergic receptor expression in mice Published In Neuroscience
2013	Arcuate NPY controls sympathetic output and BAT function via a relay of tyrosine hydroxylase neurons in the PVN Published In Cell Metabolism
2013	Association between DBH 19bp insertion/deletion polymorphism and cognition in first-episode schizophrenic patients Published In Schizophrenia Research
2013	DHA prevents altered 5-HT1A, 5-HT2A, CB1 and GABAA receptor binding densities in the brain of male rats fed a high-saturated-fat diet Published In Journal of Nutritional Biochemistry
2013	Diabetes and cognitive deficits in chronic schizophrenia: a case-control study Published In PLoS One
2013	Effects of olanzapine and betahistine co-treatment on serotonin transporter, 5-HT2A and dopamine D2 receptor binding density Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2013	Erratum: Arcuate NPY controls sympathetic output and BAT function via a relay of tyrosine hydroxylase neurons in the PVN (Cell Metabolism 17 (236-248)) Published In Cell Metabolism
2013	High-dose mushroom increases hepatic accumulation of triacylglycerol in rats fed with high-fat diet Published In Annals of Nutrition and Metabolism: European journal of nutrition, metabolic diseases and dietetics
2013	In vivo pharmacological evaluations of novel olanzapine analogues in rats: a potential new avenue for the treatment of schizophrenia Published In PLoS One
2013	Mechanism for the synergistic effect of rapamycin and resveratrol on hyperinsulinemia may involve the activation of protein kinase B Published In Cell Death and Disease
2013	Metabotropic glutamate receptor 5 binding and protein expression in schizophrenia and following antipsychotic drug treatment Published In Schizophrenia Research
2013	Molecular evidence of N-methyl-D-aspartate receptor hypofunction in schizophrenia Published In Molecular Psychiatry
2013	Neuregulin-1 signalling and antipsychotic treatment: potential therapeutic targets in a schizophrenia candidate signalling pathway Published In Psychopharmacology
2013	Reduction of histamine H1 receptor binding induced by high-fat diet can be prevented by DHA and dietary fiber in specific brain areas of male rats Published In Brain Research Bulletin
2013	S.12.1 - CANNABINOIDS Published In Behavioural Pharmacology
2013	Second generation antipsychotic-induced type 2 diabetes: a role for the muscarinic M3 receptor Published In CNS Drugs
2013	Sensitive and selective dopamine determination in human serum with inkjet printed Nafion/MWCNT chips Published In Electrochemistry Communications
2013	Teasaponin reduces inflammation and central leptin resistance in diet-induced obese male mice Published In Endocrinology
2013	The role of ghrelin signalling in second-generation antipsychotic-induced weight gain Published In Psychoneuroendocrinology
2013	The role of hypothalamic H1 receptor antagonism in antipsychotic-induced weight gain Published In CNS Drugs
2013	Transmembrane domain Nrg1 mutant mice show altered susceptibility to the neurobehavioural actions of repeated THC exposure in adolescence Published In International Journal of Neuropsychopharmacology
2012	14:15 SHEDDING LIGHT ON THE MOLECULAR BASIS FOR NMDAR HYPOFUNCTION IN SCHIZOPHRENIA Published In Schizophrenia Research
2012	Alterations to melanocortinergic, GABAergic and cannabinoid neurotransmission associated with olanzapine-induced weight gain Published In PLoS One
2012	Are there different neural mechanisms responsible for three stages of weight gain development in anti-psychotic therapy: Temporally based hypothesis Published In Asian Journal of Psychiatry
2012	Carbon Nanotube Nanoweb-Bioelectrode for Highly Selective Dopamine Sensing Published In ACS Applied Materials and Interfaces
2012	Developmental vitamin D deficiency alters MK-801-induced behaviours in adult offspring Published In Psychopharmacology
2012	Distinct neurobehavioural effects of cannabidiol in transmembrane domain neuregulin 1 mutant mice Published In PLoS One
2012	Effects of olanzapine on muscarinic M3 receptor binding density in the brain relates to weight gain, plasma insulin and metabolic hormone levels Published In European Neuropsychopharmacology
2012	Gender differences in cognitive function of patients with chronic schizophrenia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2012	Metabolic parameters and emotionality are little affected in G-protein coupled receptor 12 (Gpr12) mutant mice Published In PLoS One
2012	Novel olanzapine analogues presenting a reduced H1 receptor affinity and retained 5HT2A/D2 binding affinity ratio Published In BMC Pharmacology
2012	Perinatal phencyclidine treatment alters neuregulin 1/erbB4 expression and activation in later life Published In European Neuropsychopharmacology
2012	Reducing olanzapine-induced weight gain side-effect by using betahistine: a study in the rat model Published In Journal of Psychopharmacology
2012	Serum levels of polyunsaturated fatty acids are low in Chinese men with metabolic syndrome, whereas serum levels of saturated fatty acids, zinc and magnesium are high Published In Nutrition Research
2012	Structural contributions of antipsychotic drugs to their therapeutic profiles and metabolic side effects Published In Journal of Neurochemistry
2012	The comparison of the effect of oat and Shiitake mushroom powder to prevent body weight gain in rats fed high fat diet Published In Food and Nutrition Sciences
2012	The dopamine b-hydroxylase 19 bp insertion/deletion polymorphism was associated with first-episode but not medicated chronic schizophrenia Published In Journal of Psychiatric Research
2011	82. Exploring the interaction between Interleukin-6 and Neuregulin-1 mutations in the pathophysiology of schizophrenia: A potential link through gp130 Published In Brain Behavior and Immunity
2011	Antipsychotic treatment and neuregulin 1 -ErbB4 signalling in schizophrenia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2011	Cannabidiol potentiates Δ9-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats Published In Psychopharmacology
2011	Density of metabotropic glutamate receptors 2 and 3 (mGluR2/3) in the dorsolateral prefrontal cortex does not differ with schizophrenia diagnosis but decreases with age Published In Schizophrenia Research
2011	Diet high in oat β-glucan activates the gut-hypothalamic (PYY3-36-NPY) axis and increases satiety in diet-induced obesity in mice Published In Molecular Nutrition and Food Research
2011	Dietary Shiitake mushroom (Lentinus edodes) prevents fat deposition and lowers triglyceride in rats fed a high-fat diet
2011	Insulin caused drug resistance to oxaliplatin in colon cancer cell line HT29 Published In JOURNAL OF GASTROINTESTINAL ONCOLOGY
2011	Insulin decreases therapeutic efficacy in colon cancer cell line HT29 via the activation of the PI3K/Akt pathway Published In Current Drug Discovery Technologies
2011	Olanzapine treatment and metabolic dysfunction: a dose response study in female Sprague Dawley rats Published In Behavioural Brain Research
2011	Potential control of risperidone-related cognitive deficits by adjunctive aripiprazole treatment Published In Journal of Clinical Psychopharmacology
2011	Reciprocal signalling between NR2 subunits of the NMDA receptor and neuregulin 1 and their role in schizophrenia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2011	Sex difference in QTc prolongation in chronic institutionalized patients with schizophrenia on long-term treatment with typical and atypical antipsychotics Published In Psychopharmacology
2011	Simvastatin prevents dopaminergic neurodegeneration in experimental parkinsonian models: the association with anti-inflammatory responses Published In PLoS One
2011	The schizophrenia susceptibility gene neuregulin 1 modulates tolerance to the effects of canabinoids Published In International Journal of Neuropsychopharmacology
2010	A behavioural comparison of acute and chronic ∆9-tetrahydrocannabinol and cannabidiol in C57BL/6JArc mice Published In International Journal of Neuropsychopharmacology
2010	Activation of signal pathways and the resistance to anti-EGFR treatment in colorectal cancer Published In Journal of Cellular Biochemistry
2010	Alterations in 5-HT2A receptor binding in various brain regions among 6-hydroxydopamine-induced Parkinsonian rats Published In Synapse (New York)
2010	Beta-glucan may play an important role in algae hypocholesterolemia effect Published In European Journal of Nutrition
2010	Comment on: dietary flavonoids suppress azoxymethane-induced colonic preneoplastic lesions in male C57BL/Ksj-db/db mice Published In Chemico-Biological Interactions
2010	Cytokine alterations in the Neuregulin-1 knockout mouse model of schizophrenia Published In Brain, Behavior, and Immunity
2010	Effects of antipsychotic drugs on muscarinic M1 receptors in the rat brain Published In Australian and New Zealand Journal of Psychiatry
2010	Effects of simvastatin and 6-hydroxydopamine on histaminergic H1 receptor binding density in rat brains Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2010	Effects of typical and atypical antipsychotics on the expressions of neuregulin 1 and ERBB4 receptors Published In Australian and New Zealand Journal of Psychiatry
2010	Examining the pathways linking chronic sleep restriction to obesity
2010	No change in 3H-Ifenprodil binding sites for the NR2B subunit in the prefrontal cortex in schizophrenia Published In Australian and New Zealand Journal of Psychiatry
2010	Oat β-glucan supplementation does not enhance the effectiveness of an energy-restricted diet in overweight women Published In The British Journal of Nutrition: an international journal of nutritional science
2010	Obesity and pancreatic cancer: possible role of the PI3K/Akt pathway Published In Surgery
2010	Olanzapine decreases POMC MRNA expression and M3 receptors binding density in the hypothalamus and brainstem: pathway for weight gain side-effect? Published In Australian and New Zealand Journal of Psychiatry
2010	Olanzapine decreases cannabinoid CB1 receptors in the hypothalamus and brainstem, possibly through muscarinic M3 receptor antagonism Published In International Journal of Neuropsychopharmacology
2010	Perinatal phencyclidine (PCP) treatment in schizophrenia research: of mice and rats Published In Australian and New Zealand Journal of Psychiatry
2010	Potential control of antipsychotic-induced hyperprolactinemia and obesity in children and adolescents by aripiprazole Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2010	Reduce the olanzapine-induced body weight gain with histamine H1 receptor agonist betahistine in rats Published In International Journal of Neuropsychopharmacology
2010	Sensitivity of the female rat to olanzapine-induced weight gain - far from the clinic? Published In Schizophrenia Research
2010	Short term effects of energy restriction and dietary fat sub-type on weight loss and disease risk factors Published In Nutrition Metabolism and Cardiovascular Diseases
2010	Soluble fibre and weight control: oat β-glucan in energy restricted diets Published In Nutrition and Dietetics
2010	The PI3K/Akt pathway may play a key role in social isolation-caused schizophrenia comment re: increased dopamine D2High receptors in rats reared in social isolation Published In Synapse (New York)
2010	The role of histaminergic H1 and H3 receptors in food intake:-A mechanism fo atypical antipsychotic-induced weight gain? Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2010	The role of molecular weight and viscosity of oat β-glucan in hypocholesterolemic effect Published In American Journal of Clinical Nutrition
2010	What is the mechanism for aripiprazole's effect on reducing olanzapine-associated obesity? Published In Journal of Clinical Psychopharmacology
2009	Activation of p53 for the treatment of cancer Published In Journal of Cellular Biochemistry
2009	Acute sleep restriction alters neuroendocrine hormones and appetite in healthy male adults Published In Sleep and Biological Rhythm
2009	Adiponectin and signal pathways in obesity-induced colon cancer Published In Gut
2009	Adiponectin in obesity-associated colon cancer and its preventive implications: comment on "Association of visceral fat accumulation and adiponectin levels with colorectal neoplasia" Published In Digestive Diseases and Sciences
2009	Adiponectin is not effective against AOM-induced colon cancer but more evidence is required for its role in obesity-associated colon cancer: comment on the study by Ealey and Archer (2009) Published In International Journal of Cancer
2009	Aripiprazole differentially affects mesolimbic and nigrostriatal dopaminergic transmission: implications for long-term drug efficacy and low extrapyramidal side-effects Published In International Journal of Neuropsychopharmacology
2009	Beta-catenin pathway in ulcerative colitis-associated colorectal cancer and therapeutic implication Published In Journal of Gastrointestinal Cancer
2009	Comment on Effects of adipocyte-secreted factors on cell cycle progression in HT29 cells published by Eur J Nutr Published In European Journal of Nutrition
2009	Decreased density of serotonin 2A receptors in the superior temporal gyrus in schizophrenia - a postmortem study Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2009	Energy-restricted pair-feeding normalizes low levels of brain-derived neurotrophic factor/tyrosine kinase B mRNA expression in the hippocampus, but not ventromedial hypothalamic nucleus, in diet-induced obese mice Published In Neuroscience
2009	Excitatory and inhibitory neurotransmission is chronically altered following perinatal NMDA receptor blockade Published In European Neuropsychopharmacology
2009	High dose of simvastatin induces hyperlocomotive and anxiolytic-like activities: the association with the up-regulation of NMDA receptor binding in the rat brain Published In Experimental Neurology
2009	High-fat diet decreases tyrosine hydroxylase mRNA expression irrespective of obesity susceptibility in mice Published In Brain Research
2009	Increases in peptide Y-Y levels following oat ß-glucan ingestion are dose-dependent in overweight adults Published In Nutrition Research
2009	Inter-meal interval is increased in mice fed a high whey, as opposed to soy and gluten, protein diets Published In Appetite
2009	Interleukin-6 promotes carcinogenesis through multiple signal pathways Published In Digestive Diseases and Sciences
2009	Neuregulin 1, Brain Region Specificity and PI3K/Akt in Schizophrenia Published In European Archives of Psychiatry and Clinical Neuroscience: official organ of the German society for biological psychiatry
2009	Neuregulin 1, brain region specificity and PI3K/Akt in schizophrenia : comment on "neuregulin 1 ICE-single nucleotide polymorphism in first episode schizophrenia correlates with cerebral activation in fronto-temporal area" Published In European Archives of Psychiatry and Clinical Neuroscience: official organ of the German society for biological psychiatry
2009	Oat β-glucan increases postprandial cholecystokinin levels, decreases insulin response and extends subjective satiety in overweight subjects Published In Molecular Nutrition and Food Research
2009	Obese reversal by a chronic energy restricted diet leaves an increased Arc NPY/AgRP, but no alteration in POMC/CART, mRNA expression in diet-induced obese mice Published In Behavioural Brain Research
2009	Obesity is a major factor for colon cancer prognosis - a comment on Mehrkhani et al, 'Prognostic factors in survival of colorectal cancer patients after surgery' Published In Colorectal Disease
2009	Obesity, the P13K/Akt signal pathway and colon cancer Published In Obesity Reviews
2009	Perinatal PCP treatment alters the developmental expression of prefrontal and hippocampal muscarinic receptors Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2009	Serotonin 2A receptor and its association with the pathology of schizophrenia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2009	The effects of antipsychotic drugs administration on 5-HT1A receptor expression in the limbic system of the rat brain Published In Neuroscience
2009	The effects of developmental NMDA receptor antagonism on glutamate and acetylcholine receptor systems: a preliminary investigation of a two-hit animal model for Schizophrenia Published In Biological Psychiatry
2009	The effects of diets enriched in beta-glucans on blood lipoprotein concentrations Published In Journal of Clinical Lipidology
2009	The signal pathways in azoxymethane-induced colon cancer and preventive implications Published In Cancer Biology and Therapy
2008	A link between chronic sleep restriction and obesity: Methodological considerations Published In Public Health
2008	Altered dopamine receptor and dopamine transporter binding and tyrosine hydroxylase mRNA expression following perinatal NMDA receptor blockade Published In Neurochemical Research
2008	An investigation of the dimensionality of the Pittsburgh Sleep Quality Index in Australian adults Published In Sleep and Biological Rhythm
2008	Characterisation of a functional ingredient requires multiple assessments Published In Cereal Foods World
2008	Chronic treatment with simvastatin upregulates muscarinic M1/4 receptor binding in the rat brain Published In Neuroscience
2008	Diets High in oat-derived beta-glucan promote negative energy regulatory pathway of hypothalamic NPY system in chronic diet-induced obesity in mice Published In Obesity
2008	Differential expression of hypothalamic CART mRNA in response to body weight change following different dietary interventions Published In Neurochemistry International: the journal for the publication of cellular and molecular aspects of neurochemistry
2008	Effects of antipsychotic medication on muscarinic M1 receptor mRNA expression in the rat brain Published In Journal of Neuroscience Research
2008	Effects of chronic treatment of olanzapine and haloperidol on peptide YY binding densities in the rat brain Published In Experimental Neurology
2008	Effects of diets high in whey, soy, red meat and milk protein on body weight maintenance in diet-induced obesity in mice Published In Nutrition and Dietetics
2008	Environmental modulation of phenotype in neuregulin 1 mutants Published In International Journal of Neuropsychopharmacology
2008	High-fat diet exposure increases dopamine D2 receptor and decreases dopamine transporter receptor binding density in the nucleus accumbens and caudate putamen of mice Published In Neurochemical Research
2008	Isolation, Fractionation, and Structural Characteristics of Alkali¿Extractable ß¿Glucan from Rye Whole Meal Published In Cereal Chemistry
2008	Perinatal NMDA receptor blockade alters D2, NMDA and M1/M4 receptors in later life: implications for pathological processes of schizophrenia Published In Schizophrenia Research
2008	Perinatal administration of PCP alters adult behaviour in female Sprague-Dawley rats Published In Behavioural Brain Research
2008	Rapid cortico-limbic alterations in AMPA receptor densities after administration of PCP: implications for schizophrenia. Published In Journal of Chemical Neuroanatomy
2008	Relationships between 24 hour recalls and fasting measures of hunger and satiety: subjective and biochemical indices Published In Nutrition and Dietetics
2008	Short- and long-term effects of antipsychotic drug treatment on weight gain and H1 receptor expression Published In Psychoneuroendocrinology
2008	Temporal and site-specific brain alterations in CB1 receptor binding in high fat diet-induced obesity in C57Bl/6 mice Published In Journal of Neuroendocrinology
2008	The effects of antipsychotics on the density of cannabinoid receptors in the dorsal vagal complex of rats: Implications for olanzapine-induced weight gain Published In International Journal of Neuropsychopharmacology
2008	Ventromedial hypothalamic NPY Y2 receptor in the maintenance of body weight in diet-induced obesity in mice Published In Neurochemical Research
2007	A rodent model of NMDA receptor hypofunction for the study of schizophrenia Published In Neuroscience Bulletin
2007	A static handgrip method for distal quantitative sweat measurements Published In Neuroscience Letters
2007	AM 251 and beta-Funaltrexamine reduce fat intake in a fat-preferring strain of mouse Published In Behavioural Brain Research
2007	Alterations of muscarinic and GABA receptor binding in the posterior cingulate cortex in schizophrenia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2007	Decreased plasma peptide YY accompanied by elevated peptide YY and Y2 receptor binding densities in the medulla oblongata of diet-induced obese mice Published In Endocrinology
2007	Dietetic practice in appetite research – acute meal test studies Published In Nutrition and Dietetics
2007	Dose-dependent effects of atypical antipsychotic drug olanzapine on weight gain and cholecystokinin levels in rats Published In Neuroscience Bulletin
2007	Early brain developmental disruption from NMDA receptor hypofunction: relevance to Schizophrenia Published In Brain Research Reviews
2007	Effect of chronic treatment with clozapine and haloperidol on 5- HT2A and 2C receptor mRNA expression in the rat brain Published In Neuroscience Research
2007	Effects of typical and atypical antipsychotic drugs on rat brain muscarinic receptors Published In Neurochemical Research
2007	Histamine H1 mRNA expression is decreased in the rat hypothalamus following olanzapine treatment Published In Schizophrenia Bulletin
2007	Muscles within muscles: Coordination of 19 muscle segments within three shoulder muscles during isometric motor tasks Published In Journal of Electromyography and Kinesiology
2007	NMDA receptor hypofunction during early brain development: relevance to schizophrenia Published In Schizophrenia Bulletin
2007	No changes in cannabinoid CB1 receptor binding density in the superior temporal gyrus in schizophrenia Published In Schizophrenia Bulletin
2007	No changes in densities of cannabinoid receptors in the superior temporal gyrus in schizophrenia Published In Neuroscience Bulletin
2007	Olanzapine treatment decreases the density of muscarinic M2 receptors in the dorsal vagal complex of rats Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2007	Opposing short- and long-term effects on muscarinic M1/4 receptor binding following chronic phencyclidine treatment Published In Journal of Neuroscience Research
2007	Short and long term changes in NMDA receptor binding in mouse brain following chronic phencyclidine treatment Published In Journal of Neural Transmission
2007	The posterior cingulate cortex: a site of altered neural circuitry in schizophrenia and NMDA hypofunction Published In Schizophrenia Bulletin
2007	The transmembrane domain neuregulin 1 mutant mouse - a valuable tool for schizophrenia research? Published In Schizophrenia Bulletin
2006	Erratum: Investigation of M1/M4 muscarinic receptors in the anterior cingulate cortex in schizophrenia, bipolar disorder, and major depression disorder (Neuropsychopharmacology (2004) 29 (619-625) DOI: 10.1038/sj.npp. 1300367) Published In Neuropsychopharmacology
2003	Preparation and characterization of molecular weight standards of low polydispersity from oat and barley (1¿3)(1¿4)-ß-d-glucan Published In Food Hydrocolloids
1999	Altered hypothalamic c-Fos-like immunoreactivity in diet-induced obese mice Published In Brain Research Bulletin
1997	Fasting increases leptin receptor mRNA expression in lean but not obese (ob/ob) mouse brain Published In NeuroReport
1996	Localization of leptin receptor mRNA expression in mouse brain Published In NeuroReport

Book

Year	Title
2009	The Rhesus Monkey Brain in Stereotaxic Coordinates Publisher San Diego, California, USA

Chapter

Year	Title
2012	Organization of brainstem nuclei Published In The Human Nervous System Publisher Amsterdam
2010	Dietary fat and carbohydrate composition: Metabolic disease Published In Fat Detection: Taste, Texture, and Post Ingestive Effects Publisher Boca Raton, FL (USA)
2008	Neurodevelopment, neurotransmitter imbalance and cognitive dysfunction in schizophrenia Published In New Frontiers in Neurological Research Publisher India
2004	Chapter 10 Organization of Human Brain Stem Nuclei Published In The Human Nervous System Publisher Elsevier
1995	FIGURES Published In Atlas of the Human Brainstem Publisher Elsevier

Conference Paper

Year	Title
2017	Cannabidiol improves behavioural and glutamatergic deficits in a prenatal infection model of schizophrenia Published In 27th Annual Symposium of the International Cannabinoid Research Society
2017	Decreased 5-HT2cR and GHSR1a dimerization by olanzapine contributes to increased hypothalamic NPY and obesity side-effects Published In 7th Annual Scientific Meeting Abstract Book
2016	The Neurodevelopmental Profile of Group 1 Metabotropic Glutamate Receptors: Implications for Novel Therapeutics Published In INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
2015	Bardoxolone methyl: a potential therapeutic for the prevention of anti-psychotic drug-induced obesity? Published In Proceedings of 22nd Multidisciplinary ISBS International Neuroscience and Biological Psychiatry "Stress and Behavior" Conference
2015	MGLUR5 dysregulation in schizophrenia and cognition: from gene to protein Published In JOURNAL OF NEUROCHEMISTRY
2015	Neuropathology of muscarinic receptor in the prenatal infection – rat model Published In Biological Psychiatry Australia (BPA) Conference: Abstract Book 2015
2015	Olanzapine differentially corrects altered NMDA receptor binding induced by prenatal polyIC and LPS Published In Biological Psychiatry Australia (BPA) Conference: Abstract Book 2015
2015	Perinatal phencyclidine reduces NWASP and WAVE1 protein expression and reduces levels of myelination markers in the PFC of rats Published In JOURNAL OF NEUROCHEMISTRY
2015	Prenatal PolyIC and LPS exposure alters serotonin transporter and 5-HT2A receptor binding densities in rodents: implications for schizophrenia Published In Biological Psychiatry Australia (BPA) Conference: Abstract Book 2015
2014	Alterations of mGluR5 and mGluR5 signaling partners in schizophrenia Published In Abstracts for 2014 Society for Neuroscience Annual Meeting
2014	Effects of pharmacological blockade of Lingo - 1 signaling pathways in a phencyclidine rat model for schizophrenia Published In Abstracts for 2014 Society for Neuroscience Annual Meeting
2014	Evidence of mGluR5 dysregulation in schizophrenia Published In Australian Neuroscience Society 34th Annual Meeting
2014	MOLECULAR IMAGING OF ALTERED 18 KD TRANSLOCATOR PROTEIN (TSPO) EXPRESSION IN THE ADIPOSE TISSUE OF DIET-INDUCED OBESE MICE USING INVEON PET/CT SCANNER Published In INTERNAL MEDICINE JOURNAL
2014	Novel Implications of Lingo-1 Signaling in the Post-Mortem Schizophrenia Brain Published In BIOLOGICAL PSYCHIATRY
2014	Novel implications of Lingo-1 signaling in the prefrontal cortex and hippocampus of perinatal phencyclidine treated rats in a neurodevelopmental model of schizophrenia Published In Presentation Abstract of the Society of Biological Psychiatry 69th Annual Scientific Meeting
2013	An analysis of metabotropic glutamate receptors 2/3 and 5 in schizophrenia, major depression and bipolar disorder from the stanley neuropathology consortium Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants
2013	Central administration of histamine H1 receptor agonist, fMPH, blocks olanzapineinduced activation of ampk-cpt1 signaling in the dorsal vagal complex in rats Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants
2013	Central administrations of palmitic acid and arachidonic acid decrease central leptin sensitivity in mice Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants
2013	Effects of chronic antipsychotic treatment on dopamine synthesis Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants
2013	Leptin signalling in the dorsal vagal complex and ventrolateral medulla with age and high-fat diet induced obesity Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants
2013	Long term effects of olanzapine and betahistine on serotonin 5-HT2A receptor binding in the rat brain Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants
2013	Novel implications of Lingo-1 and its signalling partners in the Dorsolateral prefrontal cortex in schizophrenia Published In The 3rd Annual Biological Psychiatry Australia Scientific Meeting
2013	Nrg1 mutation alters cytokine responses relevant to schizophrenia Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants
2013	Subchronic metabotropic glutamate 5 receptor modulation in the perinatal pcp rodent model of schizophrenia Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants
2013	Teasaponin improves central leptin sensitivity in high-fat diet-induced obese mice Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants
2013	The therapeutic effects of an oleanolic acid derivative in diet induced obesity Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants
2013	Time-dependent ghrelinergic signaling and hyperphagia induced by olanzapine Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants
2013	Virtual screening identifies lupeol as an allosteric inhibitor of PTP1B Published In 33rd Meeting of the Australian Neuroscience Society: Program, Abstracts & List of Registrants
2012	Diagnostic-specific reductions in NMDA and mGlu5 glutamatergic receptors in schizophrenia Published In Australian Neuroscience Society 32nd Annual meeting
2012	Effects of dopamine D2 receptor partial agonist bifeprunox on body weight gain, food and water intake in male rats Published In Australian Neuroscience Society 32nd Annual meeting
2012	Effects of olanzapine and betahistine on serotonin 5-HT2A receptor binding in the rat brain Published In ANS 2012: Australian Neuroscience Society 32nd Annual meeting
2012	MGluR5 and NMDA receptor density are reduced in the dorsolateral prefrontal cortex of schizoaffective but not schizophrenia patients Published In Society of Biological Psychiatry 67th Annual Meeting
2012	Metabotropic glutamate receptor subtype 5 is reduced in schizophrenia subjects with comorbid major depression and unchanged following antipsychotic drug treatment Published In Australian Neuroscience Society 32nd Annual meeting
2012	Neuregulin1 and ErbB4 Protein Expression in Schizophrenia and their Relationship with NMDA Receptor Binding Published In BIOLOGICAL PSYCHIATRY
2012	Olanzapine treatment and time-dependent changes of hypothalamic AMPK-ACC-CPT1 signalling, food intake and body weight in rats Published In ANS 2012: Australian Neuroscience Society 32nd Annual meeting
2012	Preventing and treating olanzapine-induced obesity with betahistine: a chronic animal model study Published In The International Journal of Neuropsychopharmacology: Abstracts from the 28th CINP World Congress of Neuropsychopharmacology
2012	The effects of phencyclidine treatment on the nmdar-nrg1 signalling pathway in rats Published In Australian Neuroscience Society 32nd Annual meeting
2012	Time-dependant alterations of hypothalamic energy regulatory network by olanzapine in rats Published In Australian Neuroscience Society 32nd Annual meeting
2011	Aripiprazole selectively affects AKT/GSK protein expression in the nucleus accumbens and caudate putamen Published In 31st Annual Meeting of the Australian Neuroscience Society
2011	Cannabinoids: risk factors for a neuregulin 1 mouse model of schizophrenia? Published In 31st Annual Meeting of the Australian Neuroscience Society
2011	Development of novel antipsychotic drugs based on olanzapine that display reduced weight gain and metabolic side effects Published In EUROPEAN NEUROPSYCHOPHARMACOLOGY
2011	Differential Alterations in Glutamatergic, Dopaminergic, Cannabinoid and Cholinergic Receptors in the Brains of Neuregulin1 Mutant Mice Published In BIOLOGICAL PSYCHIATRY
2011	Histamine H1 receptor agonist and control of olanzapine-induced obesity Published In 31st Annual Meeting of the Australian Neuroscience Society
2011	INCREASED EXPRESSION OF APRIL (TNFSF13) IN DORSOLATERAL PREFRONTAL CORTEX FROM PATIENTS WITH SCHIZOPHRENIA MAY CONTRIBUTE TO ABERRANT NEUROPLASTICITY Published In SCHIZOPHRENIA BULLETIN
2011	Neuroendocrinological regulation of insulin dysfunction induced by olanzapine Published In 31st Annual Meeting of the Australian Neuroscience Society
2011	Perinatal NR2B Antagonism in Mice: An Exploratory Animal Model of Schizophrenia Published In BIOLOGICAL PSYCHIATRY
2011	Perinatal NR2B antagonism: effects on the developmental profile of NMDA receptor binding and NR2B binding in the mouse brain Published In 31st Annual Meeting of the Australian Neuroscience Society
2011	Role of ubiquitin proteasome system in schizophrenia Published In EUROPEAN NEUROPSYCHOPHARMACOLOGY
2011	The effect of phencyclidine treatment on neuregulin1 and ERBB4 receptor MRNA expression in the adult rat Published In 31st Annual Meeting of the Australian Neuroscience Society
2010	An age difference in mu opioid receptor binding density in the human putamen but no changes in schizophrenia Published In Australian Neuroscience Society Annual Meeting, Sydney 2010
2010	Diet-induced obese mice are significantly more susceptible to develop colon cancer than diet resistant mice after chronic azoxymethane treatment Published In Cancer & Obesity Conference
2010	EFFECTS OF CANNABIDIOL IN HETEROZYGOUS NEUREGULIN 1 TRANSMEMBRANE DOMAIN MUTANT MICE Published In AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
2010	EXAMINING CHANGES IN PHENCYCLIDINE-INDUCED SCHIZOPHRENIA RAT BRAIN USING MOLECULAR MASS IMAGING Published In AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
2010	Effects of simvastatin and 6-hydroxydopamine lesion on histaminergic H1 receptor binding in rat brains Published In ANS/AuPS 2010 - the 30th Annual Meeting of the Australian Neuroscience Society, in conjunction with the 50th Anniversary Meeting of the Australian Physiological Society
2010	Environmental enrichment affects PCP-induced behavioural and neurochemical symptoms of schizophrenia Published In Australian Neuroscience Society Annual Meeting, Sydney 2010
2010	GHS-R MRNA expression levels are increased in the VMH of diet-resistant mice Published In Australian Neuroscience Society Annual Meeting, Sydney 2010
2010	HOW IS NEUREGULIN 1 "KNOCKED OUT" IN THE NRG1 TRANSMEMBRANE DOMAIN HETEROZYGOUS "KNOCK-OUT" MOUSE? Published In AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
2010	Immune factors in animal models of schizophrenia Published In Australian Neuroscience Society Annual Meeting, Sydney 2010
2010	Immune factors in the Neuregulin-1 knockout mouse model of schizophrenia Published In 7th FENS Forum of European Neuroscience, 2010 Amsterdam
2010	Insulin decreases cytotoxicity of cycloheximide on HT29 and LS174T colon cancer cell lines via the PI3K/AKT pathway Published In 22nd Lorne Cancer Conference
2010	Insulin decreases the cytotoxicity of oxaliplatin in colon cancer cell HT29 Published In Cancer & Obesity Conference
2010	Long term reductions in glutamatergic NMDA and dopaminergic D1 and D2 receptors in the rat brain following adolescent, but not perinatal, MK-801 treatment Published In ANS/AuPS 2010: Australian Neuroscience Society/Australian Physiological Society Joint Meeting
2010	NMDA receptor and neuregulin1 signalling in the perinatal phencyclidine (PCP) animal model of schizophrenia Published In 7th FENS Forum of European Neuroscience, 2010 Amsterdam
2010	Neuregulin1 and ERBB4 protein expression in the rat brain following perinatal phencyclidine treatment Published In ANS/AuPS 2010: Australian Neuroscience Society/Australian Physiological Society Joint Meeting
2010	Neuregulin1 and ErbB4 protein levels are altered in the rat brain following perinatal NMDA receptor antagonism: implications for schizophrenia Published In 7th FENS Forum of European Neuroscience, 2010 Amsterdam
2010	Olanzapine decreases [3H]SR141716A binding to cannabinoid CB1 receptors in the rat hippocampus and auditory cortex: a dosage-dependent response Published In Australian Neuroscience Society Annual Meeting, Sydney 2010
2010	Olanzapine-induced metabolic dysfunction: a role for central muscarinic M3 receptors Published In Australian Neuroscience Society Annual Meeting, Sydney 2010
2010	PLASMA INTERLEUKIN-6 AND GRANULOCYTE-COLONY STIMULATING FACTOR ARE DIFFERENTIALLY EXPRESSED IN THE NEUREGULIN-1 KNOCKOUT MOUSE MODEL OF SCHIZOPHRENIA FOLLOWING IMMUNE STIMULATION Published In AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
2010	Shiitake mushroom beta-glucan but not oat beta glucan prevents body weight gain in rats fed a high fat diet Published In Proceedings of the Nutrition Society of Australia: Thirty-fourth Annual Scientific Meeting of the Nutrition Society of Australia (vol.34)
2010	THE RELEVANCE OF NEUREGULIN 1 MOUSE MODELS FOR SCHIZOPHRENIA RESEARCH AND HOW CANNABINOIDS IMPACT ON ONE PARTICULAR MODEL Published In AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
2010	THE SCHIZOPHRENIA SUSCEPTIBILITY GENE NEUREGULIN 1 CONFERS VULNERABILITY TO PERSISTENT CANNABINOID-INDUCED ANXIETY AND FOS EXPRESSION IN THE LATERAL SEPTUM Published In AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
2010	The dosage response to the side-effect of metabolic dysfunction in female rats following olanzapine treatment Published In Australian Neuroscience Society Annual Meeting, Sydney 2010
2010	The effect of perinatal and adolescent brain development disruption from NMDA receptor antagonism on CB1 receptor levels in the rat prefrontal cortex Published In Australian Neuroscience Society/Australian Physiological Society
2010	The effects of phencyclidine on the NMDAR/Neuregulin1 signalling complex: implications for schizophrenia Published In Australian Neuroscience Society/Australian Physiological Society
2009	Developmental vitamin D (DVD) deficiency alters MK-801 induced locomotion and glutamatergic rceptor binding Published In Australian Neuroscience Society Inc 29th Annual Meeting
2009	Related pathological changes of serotonin 2A, muscarinic M1 and GABA A receptors in the superior temporal gyrus in schizophrenia Published In Australian Neuroscience Society Annual Meeting
2009	The Effects of Developmental NMDA Receptor Antagonism on Glutamate and Acetylcholine Receptor Systems: A Preliminary Investigation of a Two-Hit Animal Model for Schizophrenia Published In BIOLOGICAL PSYCHIATRY
2008	A mouse model for the schizophrenia candidate gene Neuregulin 1 - mechanisms behind an age-dependent and D9-tetrahydrocannabinol-sensitive behavioural phenotype Published In 18th Annual Symposium of the International Cannabinoid Research Society
2008	Cholecystokinin mRNA expression in the arcuate hypothalamic nuclei in diet-induced obese and obese resistant mice Published In 6th Forum of European Neuroscience Abstract Volume 4
2007	A negative association between the CB1 receptor mRNA expression and high fat intake during the course of diet-induced obesity in mice Published In 17th Neuropharmacology Conference: Cannabinoid Signalling in the Nervous System
2007	Antipsychotic drugs increase food intake and cannabinoid CB1 receptor mRNA expression in the brain of rats Published In 17th Neuropharmacology Conference: Cannabinoid Signalling in the Nervous System
2007	Behavioural investigation of a neuregulin 1 knockout model in schizophrenia research Published In 7th IBRO World Congress of Neuroscience
2007	Effects of antipsychotic drugs on weight gain and CB1 receptors in the dorsal vagal complex of rats Published In 7th IBRO World Congress of Neuroscience
2007	Effects of antipsychotics on muscarinic M1 receptor mRNA expression in the rat brain Published In 7th IBRO World Congress of Neuroscience
2007	Effects of perinatal NMDA receptor antagonist treatment on dopaminergic system development and behaviour Published In 7th IBRO World Congress of Neuroscience
2007	Long-term consequences of early brain development disruption on neurochemical balance and behaviour Published In 7th IBRO World Congress of Neuroscience
2007	Phencyclidine induces apoptosis in the brain of neonatal but not adolescent and adult rats Published In 7th IBRO World Congress of Neuroscience
2007	Region-specific CB1 receptor changes in the rodent brain following NMDA receptor antagonism Published In 7th IBRO World Congress of Neurosciences
2007	The CB1 receptor as a target for the preferential reduction of high fat diet intake Published In 7th IBRO World Congress of Neuroscience
2007	The role of CART peptide in obesity development and dietary intervention Published In 7th IBRO World Congress of Neuroscience
2007	The role of Pyy and H1 histamine receptor expression in chronic diet-induced obese and diet-resistant mice Published In 7th IBRO World Congress of Neuroscience
2006	Brain development disruption from PCP causes behavioural deficits in the forced swim test in later life Published In AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
1995	Comparative distribution of receptors for amylin and the related peptides calcitonin gene related peptide and calcitonin in rat and monkey brain Published In Canadian Journal of Physiology and Pharmacology
1995	IN-VITRO AUTORADIOGRAPHIC LOCALIZATION OF CALCITONIN RECEPTORS IN MONKEY BRAIN Published In JOURNAL OF NEUROCHEMISTRY

Presentations

Invited Talk
- The mechanism of antipsychotic drug action, Invited speaker, Biological Psychiatry 2019

Investigator On

Year	Title
2021	Barnes Mazes for rats and mice Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2020	Neurite deficits, obesity and cortical thinning: Prevention and treatment in schizophrenia Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Investigator Grants
2019	GoBlot machines and Leica Objective Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2019	Rat activity wheel and living chamber system Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2019	The influence of diet on the microbiome and the subsequent manifestation of metabolic disease including non-alcoholic fatty liver disease Awarded by: NUW Alliance Funding Scheme: Grant
2019	Volumetric Imaging Facility: Observing the Cell in its Native Environment Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2018	Forced exercise/walking wheel system for rats Model 80805A Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2014 - 2017	Application of intelligent conducting polymers for treating schizophrenia and allied disorders focusing on neuronal outgrowth, myelination and synaptogenesis Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2016	Contributions to Leica Dmi8 microscope Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2016	Small animal stereotaxic instrument and microinjection unit Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2012 - 2016	Schizophrenia: reversal of antipsychotic drug-induced obesity and its related metabolic disorders Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2014	Regional flow cytometry facility Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2014	SR-LAB ABS System Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2013	Neon Transfection System: Workstation for transfer of genetic material into hard-to-work-with cells Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2013	Roles of muscarinic M3 receptors in antipsychotic-induced metabolic side-effects: prevention and treatment of anti-psychotic insulin dysregulation Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2012	How do distinct fatty acids affect central leptin sensitivity and glucose intolerance in obesity and Type II diabetes? Awarded by: Diabetes Australia Funding Scheme: Research Grant
2012	Integrated facility for confocal imaging and single molecule flourescence analysis Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2012	Investigating the interaction between inflammation, obesity and colon cancer Awarded by: Australian Institute of Nuclear Science and Engineering (AINSE) Funding Scheme: Research Awards
2011	Eppendorf MasterCycler Pro thermocycler Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2011	In vitro gut fermentation system Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2011	The use of triterpene saponins from traditional medicinal herbs for improving leptin sensitivity and glucose intolerance in obesity and Type 2 diabetes Awarded by: Diabetes Australia Funding Scheme: Research Grant
2010	Precellys 24 tissue homogenizer and digital microplate shaker Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2010	Regional facility for molecular characterisation and mapping Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2010	Schizophrenia: prevention and treatment of atypical antipsychotic drug-induced obesity Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2009	Equipment for a molecular pathology laboratory Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2009	NMDA receptor/neuregulin 1 signalling in response to phencyclidine administration Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2009	Peripheral Benzodiazapine as an early Marker for Obesity and Inflammation: Implications for Development of Type II Diabetes Mellitus and Cancer Awarded by: Australian Institute of Nuclear Science and Engineering (AINSE) Funding Scheme: Research Award
2009	Unique state-of-the-art lipidomics infrastructure Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2008	Is a higher intake of omega-3 fatty acids advantageous for weight loss? Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2008	The role of cannabis in an Nrg 1 animal model of genetic vulnerability to schizophrenia Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2008	To obtain vital laboratory equipment dedicated to radioactive lab work and thus provide safer working conditions Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
	Australian Centre for Cannabinoid Clinical and Research Excellence (ACRE): Quality and safety in the implementation of medicinal cannabis use in the community Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Centres of Research Excellence
	Lumenera Infinity 2-5 microscope colour camera Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant

Impact Story

Available as Research Supervisor

Potential Supervision Topics

1. The mechanism of anti-psychotic drug action for schizophrenia;
2. Neural branching repair for a better neural connectivity and networking;
3. How to use flowcytometry and cell imaging skills to study pathological based cells

Advisees

Graduate Advising Relationship

Degree	Research Title	Advisee
Doctor of Philosophy	The role of olanzapine-induced autophagy in the hypothalamic energy regulatory pathwsay	Boz, Zehra
Doctor of Philosophy (Integrated)	The role of D2R and NR2B interaction in neurite regulation	Xie, Yuanyi
Doctor of Philosophy	Bipolar Electroactive Conducting Polymers for Wireless Cell Stimulation	Qin, Chunyan
Doctor of Philosophy	Prevention of brain inflammation affecting neural connectivity in schizophrenia	Dongol, Anjila
Doctor of Philosophy	Advanced nanoceramic composite for health protection applications.	Rehman, Yaser
Doctor of Philosophy (Integrated)	The Molecular Mechanism of Microbiota-Gut-Brain Axis Influenced by Dietary Fibre Types	Wang, Zhizhen
Doctor of Philosophy	Prevention and treatment of antipsychotic drug-induced cortical thinning.	Chen, Xi
Doctor of Philosophy	An Investigation of the Kynurenine Pathway in Major Depression	Brown, Samara
Doctor of Philosophy	Ageing Affected by Antipsychotics	Nagaratnam, Nathan

Education And Training

Ph.D. in Neuropharmacology, University of Wollongong, School of Medicine, Neural connectivity 2018 -

Keywords

neuropharmacology, molecular nutrition, mental health, schizophrenia, type 2 diabetes, obesity, antipsychotic drug

Full Name

Xu-Feng Huang

Mailing Address

Room 305 Illawarra Health and Medical Research Institute and University of Wollongong

North field avenue

Wollongong

NSW

2500

Australia

Geographic Location

Campus

Located In Facility

IHMRI

Orcid Id

http://orcid.org/0000-0002-5895-2253 (confirmed)

Web Of Science Researcher Id

H-7408-2015

Scopus Id

12762323800" title="Scopus ID Link" target="_blank">12762323800

Top Publications

Year	Title
2009	The Rhesus Monkey Brain in Stereotaxic Coordinates
2019	Aripiprazole and haloperidol protect neurite lesions via reducing excessive D2R-DISC1 complex formation Published in Progress in Neuro-Psychopharmacology and Biological Psychiatry
2018	Dietary Galacto-Oligosaccharides and Resistant Starch Protect Against Altered CB1 and 5-HT1A and 2A Receptor Densities in Rat Brain: Implications for Preventing Cognitive and Appetite Dysfunction During a High-Fat Diet Published in Molecular Nutrition and Food Research
2019	Effects of antipsychotic drugs on neurites relevant to schizophrenia treatment Published in Medicinal Research Reviews
2018	Electrical Stimulation with a Conductive Polymer Promotes Neurite Outgrowth and Synaptogenesis in Primary Cortical Neurons in 3D Published in Scientific Reports
2015	Gender differences in cognitive deficits in schizophrenia with and without diabetes Published in Comprehensive Psychiatry
2017	Gender differences measured by the MATRICS consensus cognitive battery in chronic schizophrenia patients Published in Scientific Reports
2017	Molecular mechanisms of antipsychotic drug-induced diabetes Published in Frontiers in Neuroscience
2019	Patients with drug-naive bipolar disorder in remission after 8 weeks of treatment had decreased serum uric acid concentrations Published in Frontiers in Psychiatry
2018	Serum NCAM levels and cognitive deficits in first episode schizophrenia patients versus health controls Published in Schizophrenia Research

Research Areas

Research Overview

Publications: He has published 253 full research papers, 3 books, 9 book chapters and attracted more than 12,999 citations (Google Scholar 2020). He has an h-index of 57, with 24 publications having over 100 cites – He received an average 912 cites per year over the last 10 years, and 1,116 cites per year for the last 5 years (GS). In the last 10 years, he published 162 primary research papers, of which 94 are in the top 10% of journals (SJR), and 22 are in the top 10% for number of citations, for his field, worldwide (SciVal)–reflecting the impact his research program has had on the field.

Collaborations: He has an extensive collaboration network with world leading research laboratories both nationally and internationally. This enables him to access advanced knowledge, skills, equipment, and databases, to receive international and industry research funding, and to attract highly talented HDR students and postdoctoral research fellows.

Supervision and mentoring of Postdoctoral Fellows and Postgraduate Students: He has successfully mentored postgraduate completions comprising 12 PhD and 4 Masters students, as well as 4 Honours students in the last 5 years. Over his research career, He has mentored 14 postdoctoral fellows, 8 international visiting fellows and 6 research assistants. He received the University of Wollongong Vice Chancellor’s Excellence in Research Supervision Award in 2010.

Contribution to NHMRC, ARC and Peer review involvement: He has been an external assessor reviewing various project grants including for NHMRC from 1997 to present, IHMRI from 2012 to 2015, Schizophrenia Research Institute from 2010 to 2015, Medical Research Commercialisation Fund from 2012 to 2013, ARC Future Fellowship in 2012 and Diabetes Australia 2011-2013. He is Editorial Board Member for Frontier Neuroscience, International J of Obesity, Basic Sciences of Medicine, and a reviewer for more than 20 leading international referred journals.

Geographic Focus

Australia Country

Head Of

University of Wollongong Professor 2004 -

Member Of

Illawarra Health and Medical Research Institute Professor 2010 -

Clinical Activities

Neuropharmacology and Molecular nutrition for Schizophrenia Associate Investigator 2015 -

Selected Publications

Journal Article

Year	Title
2021	Cannabidiol regulates CB1-pSTAT3 signaling for neurite outgrowth, prolongs lifespan, and improves health span in Caenorhabditis elegans of Aß pathology models Published In FASEB Journal
2021	Defect-Rich La2O3Nanoparticles with Antioxidant Activity for Human Keratinocytes Published In ACS Applied Nano Materials
2021	Olanzapine Induces Inflammation and Immune Response via Activating ER Stress in the Rat Prefrontal Cortex Published In Current Medical Science
2021	Olanzapine-Induced Activation of Hypothalamic Astrocytes and Toll-Like Receptor-4 Signaling via Endoplasmic Reticulum Stress Were Related to Olanzapine-Induced Weight Gain Published In Frontiers in Neuroscience
2021	The Role of Butyric Acid in Treatment Response in Drug-Naïve First Episode Schizophrenia. Published In Front Psychiatry
2021	The kynurenine pathway in major depression: What we know and where to next Published In Neuroscience and Biobehavioral Reviews
2021	Theranostic two-dimensional superparamagnetic maghemite quantum structures for ROS-mediated cancer therapy Published In Journal of Materials Chemistry B
2021	ß-Glucan from Lentinula edodes prevents cognitive impairments in high-fat diet-induced obese mice: involvement of colon-brain axis Published In Journal of Translational Medicine
2020	A synergistic effect between family intervention and rTMS improves cognitive and negative symptoms in schizophrenia: A randomized controlled trial Published In Journal of Psychiatric Research
2020	Bipolar electroactive conducting polymers for wireless cell stimulation Published In Applied Materials Today
2020	Curdlan Prevents the Cognitive Deficits Induced by a High-Fat Diet in Mice via the Gut-Brain Axis Published In Frontiers in Neuroscience
2020	DHA reduces hypothalamic inflammation and improves central leptin signaling in mice Published In Life Sciences
2020	Data on the bipolar electroactive conducting polymers for wireless cell stimulation Published In Data in Brief
2020	Decreased serum NCAM is positively correlated with hippocampal volumes and negatively correlated with positive symptoms in first-episode schizophrenia patients Published In Journal of Psychiatric Research
2020	Insulin Resistance and Oxidative Stress: In Relation to Cognitive Function and Psychopathology in Drug-Naïve, First-Episode Drug-Free Schizophrenia Published In Frontiers in Psychiatry
2020	Investigation of ROS scavenging properties and in vitro cytotoxicity of oxygen-deficient La2O3-x nanostructure synthesized by spray pyrolysis method Published In JOURNAL OF NANOSTRUCTURE IN CHEMISTRY
2020	N-acetylcysteine prevents olanzapine-induced oxidative stress in mHypoA-59 hypothalamic neurons Published In Scientific Reports
2020	Olanzapine increases AMPK-NPY orexigenic signaling by disrupting H1R-GHSR1a interaction in the hypothalamic neurons of mice Published In Psychoneuroendocrinology
2020	Prevention of Neurite Spine Loss Induced by Dopamine D2 Receptor Overactivation in Striatal Neurons Published In Frontiers in Neuroscience
2020	Risperidone stimulates food intake and induces body weight gain via the hypothalamic arcuate nucleus 5-HT2c receptor¿NPY pathway Published In CNS Neuroscience and Therapeutics
2020	Supplement of microbiota-accessible carbohydrates prevents neuroinflammation and cognitive decline by improving the gut microbiota-brain axis in diet-induced obese mice Published In Journal of Neuroinflammation
2020	ß-glucan attenuates cognitive impairment via the gut-brain axis in diet-induced obese mice Published In Microbiome
2019	Alterations to the microbiota–colon–brain axis in high-fat-diet-induced obese mice compared to diet-resistant mice Published In Journal of Nutritional Biochemistry
2019	An alternating least square based algorithm for predicting patient survivability Published In Communications in Computer and Information Science
2019	Aripiprazole and haloperidol protect neurite lesions via reducing excessive D2R-DISC1 complex formation Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2019	Cannabidiol improves behavioural and neurochemical deficits in adult female offspring of the maternal immune activation (poly I:C) model of neurodevelopmental disorders Published In Brain, Behavior, and Immunity
2019	Effect of cannabidiol on endocannabinoid, glutamatergic and GABAergic signalling markers in male offspring of a maternal immune activation (poly I:C) model relevant to schizophrenia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2019	Effects of antipsychotic drugs on neurites relevant to schizophrenia treatment Published In Medicinal Research Reviews
2019	Increased translocator protein (TSPO) binding throughout neurodevelopment in the perinatal phencyclidine rodent model of schizophrenia Published In Schizophrenia Research
2019	Nano-sunscreens – a double-edged sword in protecting consumers from harm: viewing Australian regulatory policies through the lenses of the European Union Published In Critical Reviews in Toxicology
2019	Olanzapine-induced endoplasmic reticulum stress and inflammation in the hypothalamus were inhibited by an ER stress inhibitor 4-phenylbutyrate Published In Psychoneuroendocrinology
2019	Patients with drug-naive bipolar disorder in remission after 8 weeks of treatment had decreased serum uric acid concentrations Published In Frontiers in Psychiatry
2019	Sensitivity of plasma cholecystokinin and peptide YY in obese and normal weight men Published In Malaysian Journal of Nutrition
2019	Tacrine-Hydrogen Sulfide Donor Hybrid Ameliorates Cognitive Impairment in the Aluminum Chloride Mouse Model of Alzheimer's Disease Published In ACS Chemical Neuroscience
2019	The gut microbiota promotes the pathogenesis of schizophrenia via multiple pathways Published In Biochemical and Biophysical Research Communications
2018	3D imaging of PSD-95 in the mouse brain using the advanced CUBIC method Published In Molecular Brain
2018	A postmortem analysis of NMDA ionotropic and group 1 metabotropic glutamate receptors in the nucleus accumbens in schizophrenia Published In Journal of Psychiatry and Neuroscience
2018	Association between hyperuricemia and metabolic syndrome in patients suffering from bipolar disorder Published In BMC Psychiatry
2018	Changes in metabolism and microbiota after 24-week risperidone treatment in drug naïve, normal weight patients with first episode schizophrenia Published In Schizophrenia Research
2018	Chronic Adolescent CDPPB Treatment Alters Short-Term, but not Long-Term, Glutamatergic Receptor Expression Published In Neurochemical Research
2018	Cold exposure promotes obesity and impairs glucose homeostasis in mice subjected to a highfat diet Published In Molecular Medicine Reports
2018	Commentary: GLYX-13 Ameliorates Schizophrenia-Like Phenotype Induced by MK-801 in Mice: Role of Hippocampal NR2B and DISC1 Published In Frontiers in Molecular Neuroscience
2018	Decreased 5‐HT2cR and GHSR1a interaction in antipsychotic drug‐induced obesity Published In Obesity Reviews
2018	Dietary Galacto-Oligosaccharides and Resistant Starch Protect Against Altered CB1 and 5-HT1A and 2A Receptor Densities in Rat Brain: Implications for Preventing Cognitive and Appetite Dysfunction During a High-Fat Diet Published In Molecular Nutrition and Food Research
2018	Disrupted sphingolipid metabolism following acute clozapine and olanzapine administration Published In British Journal of Biomedical Science
2018	Early antipsychotic treatment in juvenile rats elicits long-term alterations to the adult serotonin receptors Published In Neuropsychiatric Disease and Treatment
2018	Effect of multi-walled carbon nanotubes on the cross-linking density of the poly(glycerol sebacate) elastomeric nanocomposites Published In Journal of Colloid and Interface Science
2018	Effects of short- and long-term aripiprazole treatment on Group I mGluRs in the nucleus accumbens: Comparison with haloperidol Published In Psychiatry Research
2018	Electrical Stimulation with a Conductive Polymer Promotes Neurite Outgrowth and Synaptogenesis in Primary Cortical Neurons in 3D Published In Scientific Reports
2018	Epidemiology of birth defects based on surveillance data from 2011-2015 in Guangxi, China: comparison across five major ethnic groups Published In BMC PUBLIC HEALTH
2018	Galantamine improves cognition, hippocampal inflammation, and synaptic plasticity impairments induced by lipopolysaccharide in mice Published In Journal of Neuroinflammation
2018	Ginsenoside Rb1 improves leptin sensitivity in the prefrontal cortex in obese mice Published In CNS Neuroscience and Therapeutics
2018	Liraglutide prevents metabolic side-effects and improves recognition and working memory during antipsychotic treatment in rats Published In Journal of Psychopharmacology
2018	Microglia activation in the offspring of prenatal Poly I: C exposed rats: a PET imaging and immunohistochemistry study Published In General Psychiatry
2018	Obesity, altered oxidative stress, and clinical correlates in chronic schizophrenia patients Published In Translational Psychiatry
2018	Perinatal administration of phencyclidine alters expression of Lingo-1 signaling pathway proteins in the prefrontal cortex of juvenile and adult rats Published In Neuronal Signaling
2018	Propionate protects haloperidol-induced neurite lesions mediated by neuropeptide Y Published In Frontiers in Neuroscience
2018	RANKL reduces body weight and food intake via the modulation of hypothalamic NPY/CART expression Published In International Journal of Medical Sciences
2018	Serum NCAM levels and cognitive deficits in first episode schizophrenia patients versus health controls Published In Schizophrenia Research
2017	Alterations of ubiquitin related proteins in the pathology and development of schizophrenia: Evidence from human and animal studies Published In Journal of Psychiatric Research
2017	Association between DBH 19 bp insertion/deletion polymorphism and cognition in schizophrenia with and without tardive dyskinesia Published In Schizophrenia Research
2017	Cannabidiol rescues glutamatergic, memory and social interaction deficits following prenatal infection: a follow-up in female offspring Published In European Neuropsychopharmacology
2017	Correction: Prevalence and correlates of psychological distress among diabetes mellitus adults in the Jilin province in China: a cross-sectional study. Published In PeerJ
2017	Current views on neuropeptide Y and diabetes-related atherosclerosis Published In Diabetes and Vascular Disease Research
2017	Dietary teasaponin ameliorates alteration of gut microbiota and cognitive decline in diet-induced obese mice Published In Scientific Reports
2017	Electrical stimulation using conductive polymer polypyrrole counters reduced neurite outgrowth of primary prefrontal cortical neurons from NRG1-KO and DISC1-LI mice Published In Scientific Reports
2017	Gender differences measured by the MATRICS consensus cognitive battery in chronic schizophrenia patients Published In Scientific Reports
2017	Improved social interaction, recognition and working memory with cannabidiol treatment in a prenatal infection (poly I:C) rat model Published In Neuropsychopharmacology
2017	Intake of 7,8-dihydroxyflavone from pregnancy to weaning prevents cognitive deficits in adult offspring after maternal immune activation Published In European Archives of Psychiatry and Clinical Neuroscience: official organ of the German society for biological psychiatry
2017	Luteolin, a natural flavonoid, inhibits methylglyoxal induced apoptosis via the mTOR/4E-BP1 signaling pathway Published In Scientific Reports
2017	Molecular mechanisms of antipsychotic drug-induced diabetes Published In Frontiers in Neuroscience
2017	Prevalence and correlates of psychological distress among diabetes mellitus adults in the Jilin province in China: a cross-sectional study Published In PEERJ
2017	Prevalence and correlates of psychological distress among diabetes mellitus adults in the Jilin province in China: a cross-sectional study Published In PeerJ
2017	Probe Sensor Using Nanostructured Multi-Walled Carbon Nanotube Yarn for Selective and Sensitive Detection of Dopamine Published In Sensors
2017	Reduced serum levels of oestradiol and brain derived neurotrophic factor in both diabetic women and HFD-feeding female mice Published In Endocrine
2017	Tailoring the wettability and mechanical properties of electrospun poly(L-lactic acid)-poly(glycerol sebacate) core-shell membranes for biomedical applications Published In Journal of Colloid and Interface Science
2017	The central mechanism of risperidone-induced hyperprolactinemia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2017	Time-dependent changes and potential mechanisms of glucose-lipid metabolic disorders associated with chronic clozapine or olanzapine treatment in rats Published In Scientific Reports
2017	Time-dependent effects of olanzapine treatment on the expression of histidine decarboxylase, H1 and H3 receptor in the rat brain: The roles in olanzapine-induced obesity Published In Psychoneuroendocrinology
2016	A label-free and high-throughput separation of neuron and glial cells using an inertial microfluidic platform Published In Biomicrofluidics
2016	A splicing-regulatory polymorphism in DRD2 disrupts ZRANB2 binding, impairs cognitive functioning and increases risk for schizophrenia in six Han Chinese samples Published In Molecular Psychiatry
2016	Ameliorating antipsychotic-induced weight gain by betahistine: mechanisms and clinical implications Published In Pharmacological Research
2016	Aripiprazole and haloperidol activate GSK3β-dependent signalling pathway differentially in various brain regions of rats Published In International Journal of Molecular Sciences
2016	Aripiprazole increases the PKA signalling and expression of the GABA_A receptor and CREB1 in the nucleus accumbens of rats Published In Journal of Molecular Neuroscience
2016	Association between DβH5′ insertion/deletion polymorphism and cognition in patients with chronic schizophrenia Published In Journal of Clinical Psychiatry
2016	Bardoxolone methyl prevents high-fat diet-induced colon inflammation in mice Published In Journal of Histochemistry and Cytochemistry: imaging the spectrum of cell biology
2016	Bardoxolone methyl prevents obesity and hypothalamic dysfunction Published In Chemico-Biological Interactions
2016	Chlorogenic acid protects d-galactose-induced liver and kidney injury via antioxidation and anti-inflammation effects in mice Published In Pharmaceutical Biology
2016	Chronic administration of aripiprazole activates GSK3β-dependent signalling pathways, and up-regulates GABA_A receptor expression and CREB1 activity in rats Published In Scientific Reports
2016	Chronic rhein treatment improves recognition memory in high-fat diet-induced obese male mice Published In Journal of Nutritional Biochemistry
2016	Early antipsychotic treatment in childhood/adolescent period has long-term effects on depressive-like, anxiety-like and locomotor behaviours in adult rats Published In Journal of Psychopharmacology
2016	Early antipsychotic treatment in juvenile rats elicits long-term alterations to the dopamine neurotransmitter system Published In International Journal of Molecular Sciences
2016	Effect of a glucagon-like peptide 1 (GLP-1) receptor agonist, liraglutide, on cognition and body weight during antipsychotic treatment Published In International Journal of Neuropsychopharmacology
2016	Effect of cannabidiol on cognition in a maternal immune activation (poly IC) model of schizophrenia Published In International Journal of Neuropsychopharmacology
2016	Erratum to: MGluR2/3 agonist LY379268 rescues NMDA and GABAA receptor level deficits induced in a two-hit mouse model of schizophrenia Published In Psychopharmacology
2016	Intake of 7,8-dihydroxyflavone during juvenile and adolescent stages prevents onset of psychosis in adult offspring after maternal immune activation Published In Scientific Reports
2016	Interaction of BDNF with cytokines in chronic schizophrenia Published In Brain, Behavior, and Immunity
2016	Neurodevelopmental expression profile of dimeric and monomeric group 1 mGluRs: relevance to schizophrenia pathogenesis and treatment Published In Scientific Reports
2016	Olanzapine prevents the PCP-induced reduction in the neurite outgrowth of prefrontal cortical neurons via NRG1 Published In Scientific Reports
2016	PM336. Early Antipsychotic Treatment in Childhood/Adolescent Period has Long-term Effects on Dopamine Receptors of Adult Rat Brains Published In The International Journal of Neuropsychopharmacology
2016	PM439. Chronic effects of aripiprazole on the GSK3ß-dependent pathways, NMDA receptor and CREB1 in the rat brain Published In The International Journal of Neuropsychopharmacology
2016	PS146. Norbin: an emerging player in the pathophysiology and treatment of depression? Published In The International Journal of Neuropsychopharmacology
2016	Protective effect of the orientin on noise-induced cognitive impairments in mice Published In Behavioural Brain Research
2016	Reversal effect of simvastatin on the decrease in cannabinoid receptor 1 density in 6-hydroxydopamine lesioned rat brains Published In Life Sciences
2016	Selective binding modes and allosteric inhibitory effects of lupane triterpenes on protein tyrosine phosphatase 1B Published In Scientific Reports
2016	Smoking and serum lipid profiles in schizophrenia Published In Neuroscience Bulletin
2016	The Neurodevelopmental Profile of Group 1 Metabotropic Glutamate Receptors: Implications for Novel Therapeutics Published In International Journal of Neuropsychopharmacology
2016	Use of conducting polymers to facilitate neurite branching in schizophrenia-related neuronal development Published In Biomaterials Science
2016	mGluR2/3 agonist LY379268 rescues NMDA and GABAA receptor level deficits induced in a two-hit mouse model of schizophrenia Published In Psychopharmacology
2015	Alterations of mGluR5 and its endogenous regulators Norbin, Tamalin and Preso1 in schizophrenia: towards a model of mGluR5 dysregulation Published In Acta Neuropathologica
2015	Alterations of p75 neurotrophin receptor and Myelin transcription factor 1 in the hippocampus of perinatal phencyclidine treated rats Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2015	Altered IL-2, IL-6 and IL-8 serum levels in schizophrenia patients with tardive dyskinesia Published In Schizophrenia Research
2015	Arachidonic acid impairs hypothalamic leptin signaling and hepatic energy homeostasis in mice Published In Molecular and Cellular Endocrinology
2015	Bardoxolone methyl prevents fat deposition and inflammation in brown adipose tissue and enhances sympathetic activity in mice fed a high-fat diet Published In Nutrients
2015	Bardoxolone methyl prevents fat deposition and inflammation in the visceral fat of mice fed a high-fat diet Published In Chemico-Biological Interactions
2015	Bardoxolone methyl prevents high-fat diet-induced alterations in prefrontal cortex signalling molecules involved in recognition memory Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2015	Bardoxolone methyl prevents insulin resistance and the development of hepatic steatosis in mice fed a high-fat diet Published In Molecular and Cellular Endocrinology
2015	Bardoxolone methyl prevents mesenteric fat deposition and inflammation in high-fat diet mice Published In The Scientific World Journal
2015	Bardoxolone methyl prevents the development and progression of cardiac and renal pathophysiologies in mice fed a high-fat diet Published In Chemico-Biological Interactions
2015	Chronic betahistine co-treatment reverses olanzapine's effects on dopamine D2 but not 5-HT2A/2C bindings in rat brains Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2015	Cognitive differences in schizophrenia on long-term treatments with clozapine, risperidone and typical antipsychotics Published In International Clinical Psychopharmacology
2015	Differential effects of short- and long-term antipsychotic treatment on the expression of neuregulin-1 and ErbB4 receptors in the rat brain Published In Psychiatry Research
2015	Gender differences in cognitive deficits in schizophrenia with and without diabetes Published In Comprehensive Psychiatry
2015	Glucose disturbances in first-episode drug-naïve schizophrenia: relationship to psychopathology Published In Psychoneuroendocrinology
2015	High fat diet-induced obesity increases the formation of colon polyps induced by azoxymethane in mice Published In Annals of Translational Medicine
2015	Is B-type natriuretic peptide a risk factor for heart failure in patients treated with bardoxolone methyl? Published In Journal of Cardiac Failure
2015	Metabotropic glutamate receptor 5, and its trafficking molecules Norbin and Tamalin, are increased in the CA1 hippocampal region of subjects with schizophrenia Published In Schizophrenia Research
2015	NMDA receptor antagonism by phencyclidine reduces NWASP and WAVE1 protein expression and reduces levels of myelination markers in the prefrontal cortex of rats Published In Journal of Pharmaceutics & Pharmacology
2015	Neuregulin 1 expression and electrophysiological abnormalities in the Neuregulin 1 transmembrane domain heterozygous mutant mouse Published In PLoS One
2015	Neuregulin 1 prevents phencyclidine-induced behavioral impairments and disruptions to GABAergic signaling in mice Published In International Journal of Neuropsychopharmacology
2015	Orientin improves depression-like behavior and BDNF in chronic stressed mice Published In Molecular Nutrition and Food Research
2015	Palmitic acid induces central leptin resistance and impairs hepatic glucose and lipid metabolism in male mice Published In Journal of Nutritional Biochemistry
2015	Possible association between DBH 19 bp insertion/deletion polymorphism and clinical symptoms in schizophrenia with tardive dyskinesia Published In Journal of Neural Transmission
2015	Preimplantation exposure to Bisphenol A and Triclosan may lead to implantation failure in humans Published In BioMed Research International
2015	Teasaponin improves leptin sensitivity in the prefrontal cortex of obese mice Published In Molecular Nutrition and Food Research
2015	Unique effects of acute aripiprazole treatment on the dopamine D2 receptor downstream cAMP-PKA and Akt-GSK3β signalling pathways in rats Published In PLoS One
2014	A high-dose Shiitake mushroom increases hepatic accumulation of triacylglycerol in rats fed a high-fat diet: underlying mechanism Published In Nutrients
2014	Alterations of NMDA receptor binding in various brain regions among 6-hydroxydopamine-induced Parkinsonian rats Published In International Journal of Neuroscience
2014	Awareness, treatment, control of diabetes mellitus and the risk factors: survey results from Northeast China Published In PLoS One
2014	Betahistine ameliorates olanzapine-induced weight gain through modulation of histaminergic, NPY and AMPK pathways Published In Psychoneuroendocrinology
2014	Central inflammation and leptin resistance are attenuated by ginsenoside Rb1 treatment in obese mice fed a high-fat diet Published In PLoS One
2014	Comment on: Oleanolic acid co-administration alleviates ethanol-induced hepatic injury via Nrf-2 and ethanol-metabolizing modulation (sic) in rats Published In Chemico-Biological Interactions
2014	Different effects of Bifeprunox, Aripiprazole, and Haloperidol on body weight gain, food and water intake, and locomotor activity in rats Published In Pharmacology, Biochemistry and Behavior
2014	Dyslipidemia awareness, treatment, control and influence factors among adults in the Jilin province in China: a cross-sectional study Published In Lipids in Health and Disease
2014	Effects of olanzapine on the elevation of macrophage infiltration and pro-inflammatory cytokine expression in female rats Published In Journal of Psychopharmacology
2014	GluN2B protein deficits in the left, but not the right, hippocampus in schizophrenia Published In BMC Psychiatry
2014	Hypothalamic ghrelin signalling mediates olanzapine-induced hyperphagia and weight gain in female rats Published In International Journal of Neuropsychopharmacology
2014	Hypothalamic histamine H1 receptor-AMPK signaling time-dependently mediates olanzapine-induced hyperphagia and weight gain in female rats Published In Psychoneuroendocrinology
2014	Metabotropic glutamate receptor mGluR2/3 and mGluR5 binding in the anterior cingulate cortex in psychotic and nonpsychotic depression, bipolar disorder and schizophrenia: implications for novel mGluR-based therapeutics Published In Journal of Psychiatry and Neuroscience
2014	Novel implications of Lingo-1 and its signaling partners in schizophrenia Published In Translational Psychiatry
2014	Novel implications of lingo-1 signaling in the post-mortem schizophrenia brain Published In Biological Psychiatry
2014	Olanzapine reduced brown adipose tissue thermogenesis and locomotor activity in female rats Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2014	Olanzapine-activated AMPK signaling in the dorsal vagal complex is attenuated by histamine H1 receptor agonist in female rats Published In Endocrinology
2014	Poster #S173 METABOTROPIC GLUTAMATE RECEPTOR 5 DYSREGULATION IN SCHIZOPHRENIA Published In Schizophrenia Research
2014	Preventing olanzapine-induced weight gain using betahistine: a study in a rat model with chronic olanzapine treatment Published In PLoS One
2014	Simvastatin reverses the downregulation of M1/4 receptor binding in 6-hydroxydopamine-induced parkinsonian rats: the association with improvements in long-term memory Published In Neuroscience
2014	The differences of cognitive deficits in chronic schizophrenia on long-term treatment with typical and atypical antipsychotics Published In International Journal of Neuropsychopharmacology
2014	The endothelin pathway: a protective or detrimental target of bardoxolone methyl on cardiac function in patients with advanced chronic kidney disease? Published In American Journal of Nephrology
2014	The molecular mechanisms underpinning the therapeutic properties of oleanolic acid, its isomer and derivatives for type 2 diabetes and associated complications Published In Molecular Nutrition and Food Research
2013	A neuregulin 1 transmembrane domain mutation causes imbalanced glutamatergic and dopaminergic receptor expression in mice Published In Neuroscience
2013	Arcuate NPY controls sympathetic output and BAT function via a relay of tyrosine hydroxylase neurons in the PVN Published In Cell Metabolism
2013	Association between DBH 19bp insertion/deletion polymorphism and cognition in first-episode schizophrenic patients Published In Schizophrenia Research
2013	DHA prevents altered 5-HT1A, 5-HT2A, CB1 and GABAA receptor binding densities in the brain of male rats fed a high-saturated-fat diet Published In Journal of Nutritional Biochemistry
2013	Diabetes and cognitive deficits in chronic schizophrenia: a case-control study Published In PLoS One
2013	Effects of olanzapine and betahistine co-treatment on serotonin transporter, 5-HT2A and dopamine D2 receptor binding density Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2013	Erratum: Arcuate NPY controls sympathetic output and BAT function via a relay of tyrosine hydroxylase neurons in the PVN (Cell Metabolism 17 (236-248)) Published In Cell Metabolism
2013	High-dose mushroom increases hepatic accumulation of triacylglycerol in rats fed with high-fat diet Published In Annals of Nutrition and Metabolism: European journal of nutrition, metabolic diseases and dietetics
2013	In vivo pharmacological evaluations of novel olanzapine analogues in rats: a potential new avenue for the treatment of schizophrenia Published In PLoS One
2013	Mechanism for the synergistic effect of rapamycin and resveratrol on hyperinsulinemia may involve the activation of protein kinase B Published In Cell Death and Disease
2013	Metabotropic glutamate receptor 5 binding and protein expression in schizophrenia and following antipsychotic drug treatment Published In Schizophrenia Research
2013	Molecular evidence of N-methyl-D-aspartate receptor hypofunction in schizophrenia Published In Molecular Psychiatry
2013	Neuregulin-1 signalling and antipsychotic treatment: potential therapeutic targets in a schizophrenia candidate signalling pathway Published In Psychopharmacology
2013	Reduction of histamine H1 receptor binding induced by high-fat diet can be prevented by DHA and dietary fiber in specific brain areas of male rats Published In Brain Research Bulletin
2013	S.12.1 - CANNABINOIDS Published In Behavioural Pharmacology
2013	Second generation antipsychotic-induced type 2 diabetes: a role for the muscarinic M3 receptor Published In CNS Drugs
2013	Sensitive and selective dopamine determination in human serum with inkjet printed Nafion/MWCNT chips Published In Electrochemistry Communications
2013	Teasaponin reduces inflammation and central leptin resistance in diet-induced obese male mice Published In Endocrinology
2013	The role of ghrelin signalling in second-generation antipsychotic-induced weight gain Published In Psychoneuroendocrinology
2013	The role of hypothalamic H1 receptor antagonism in antipsychotic-induced weight gain Published In CNS Drugs
2013	Transmembrane domain Nrg1 mutant mice show altered susceptibility to the neurobehavioural actions of repeated THC exposure in adolescence Published In International Journal of Neuropsychopharmacology
2012	14:15 SHEDDING LIGHT ON THE MOLECULAR BASIS FOR NMDAR HYPOFUNCTION IN SCHIZOPHRENIA Published In Schizophrenia Research
2012	Alterations to melanocortinergic, GABAergic and cannabinoid neurotransmission associated with olanzapine-induced weight gain Published In PLoS One
2012	Are there different neural mechanisms responsible for three stages of weight gain development in anti-psychotic therapy: Temporally based hypothesis Published In Asian Journal of Psychiatry
2012	Carbon Nanotube Nanoweb-Bioelectrode for Highly Selective Dopamine Sensing Published In ACS Applied Materials and Interfaces
2012	Developmental vitamin D deficiency alters MK-801-induced behaviours in adult offspring Published In Psychopharmacology
2012	Distinct neurobehavioural effects of cannabidiol in transmembrane domain neuregulin 1 mutant mice Published In PLoS One
2012	Effects of olanzapine on muscarinic M3 receptor binding density in the brain relates to weight gain, plasma insulin and metabolic hormone levels Published In European Neuropsychopharmacology
2012	Gender differences in cognitive function of patients with chronic schizophrenia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry
2012	Metabolic parameters and emotionality are little affected in G-protein coupled receptor 12 (Gpr12) mutant mice Published In PLoS One
2012	Novel olanzapine analogues presenting a reduced H1 receptor affinity and retained 5HT2A/D2 binding affinity ratio Published In BMC Pharmacology
2012	Perinatal phencyclidine treatment alters neuregulin 1/erbB4 expression and activation in later life Published In European Neuropsychopharmacology
2012	Reducing olanzapine-induced weight gain side-effect by using betahistine: a study in the rat model Published In Journal of Psychopharmacology
2012	Serum levels of polyunsaturated fatty acids are low in Chinese men with metabolic syndrome, whereas serum levels of saturated fatty acids, zinc and magnesium are high Published In

Overview

Overview

Top Publications

Research Areas

Research Overview

Geographic Focus

Available as Research Supervisor

Affiliation

Available for Collaborative Projects

Head Of

Member Of

Clinical Activities

Publications

Selected Publications

Journal Article

Book

Chapter

Conference Paper

Presentations

Invited Talk

Funding

Investigator On

Impact

Impact Story

Supervision

Available as Research Supervisor

Potential Supervision Topics

Advisees

Graduate Advising Relationship

Background

Education And Training

Keywords

Contact

Full Name

Mailing Address

Geographic Location

Located In Facility

Identity

Orcid Id

Web Of Science Researcher Id

Scopus Id

Overview

Top Publications

Research Areas

Research Overview

Geographic Focus

Affiliation

Head Of

Member Of

Clinical Activities

Publications

Selected Publications

Journal Article