Huang, Xu-Feng

Overview

Career Summary: After the completion of a PhD at the University of New South Wales Australia (UNSW), Prof Huang received 3 years of postdoctoral training in the Schools of Psychology and Pathology at UNSW. He then joined the University of Wollongong (UOW) as a Lecturer in October, 1995. He was awarded Doctor of Science (DSc) in 2012. He initiated and established the Centre of Translational Neuroscience at UOW studying the central control of energy balance associated with obesity and neuropharmacology of antipsychotic drugs in 1999. He joined the Illawarra Health and Medical Research Institute (IHMRI) in 2010 and was subsequently appointed as Foundation Scientific Director of the Metabolic Theme from September 2010 to June 2012. From 2017 to now, he is Theme Leader of the Mental Health and Ageing Brain in IHMRI. He received the Vice-Chancellor’s Research Excellence Award for Senior Researcher of the Year 2014. From 2017 to now, he is Theme Leader for Mental Health and Ageing Brain theme in IHMRI.

Disciplinary expertise: He has broad knowledge of basic and clinical research. His expertise is in neuropharmacology, metabolism, clinical psychiatry, molecular nutrition and medical physiology. His research investigates the mechanisms of neurotransmission and intracellular signal transduction using cell and rodent models, computational modelling, and clinical studies. His publications reflect his expertise in neuropharmacology, the mechanism of antipsychotic drug action, obesity and metabolic disorders and schizophrenia.

Top Publications

Year	Title
2009	The Rhesus Monkey Brain in Stereotaxic Coordinates
2016	A label-free and high-throughput separation of neuron and glial cells using an inertial microfluidic platform Published in Biomicrofluidics
2017	Electrical stimulation using conductive polymer polypyrrole counters reduced neurite outgrowth of primary prefrontal cortical neurons from NRG1-KO and DISC1-LI mice Published in Scientific Reports
2017	Intake of 7,8-dihydroxyflavone from pregnancy to weaning prevents cognitive deficits in adult offspring after maternal immune activation Published in European Archives of Psychiatry and Clinical Neuroscience: official organ of the German society for biological psychiatry
2017	Probe Sensor Using Nanostructured Multi-Walled Carbon Nanotube Yarn for Selective and Sensitive Detection of Dopamine Published in Sensors

Research Areas

Research Overview

He has published 224 articles, which has been cited 7,145 times. In addition, his books have been cited 1,105 times. He has had 38 publications in the top 5%, and 79 publications in the top 10% most cited publications worldwide (UOW Library Report, 2016). From his research publications, there are 14 research articles cited more than 100 times, and 41 articles with more than 50 citations. In the past three years, he has had an average of over 500 citations per year, with a recent increased trajectory. He has an H-index of 46 (Google Scholar 2016).

Collaborations: He has an extensive collaboration network with world leading research laboratories both nationally and internationally. This enables him to access advanced knowledge, skills, equipment, and databases, to receive international and industry research funding, and to attract highly talented HDR students and postdoctoral research fellows.

Supervision and mentoring of Postdoctoral Fellows and Postgraduate Students: He has successfully mentored postgraduate completions comprising 12 PhD and 4 Masters students, as well as 4 Honours students in the last 5 years. Over his research career, He has mentored 14 postdoctoral fellows, 8 international visiting fellows and 6 research assistants. He received the University of Wollongong Vice Chancellor’s Excellence in Research Supervision Award in 2010.

Contribution to NHMRC, ARC and Peer review involvement: He has been an external assessor reviewing various project grants including for NHMRC from 1997 to present, IHMRI from 2012 to 2015, Schizophrenia Research Institute from 2010 to 2015, Medical Research Commercialisation Fund from 2012 to 2013, ARC Future Fellowship in 2012 and Diabetes Australia 2011-2013. He is Editorial Board Member for Frontier Neuroscience, International J of Obesity, Basic Sciences of Medicine, and a reviewer for more than 20 leading international referred journals.

Geographic Focus

Australia Country

Selected Publications

Journal Article

Year	Title
2019	Alterations to the microbiota–colon–brain axis in high-fat-diet-induced obese mice compared to diet-resistant mice Published In Journal of Nutritional Biochemistry Volume 65 Pages 54 - 65 ISSN 0955-2863 Altmetric
2019	An alternating least square based algorithm for predicting patient survivability Published In Communications in Computer and Information Science Volume 996 Pages 305 - 317 Altmetric
2019	Aripiprazole and haloperidol protect neurite lesions via reducing excessive D2R-DISC1 complex formation Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 92 Pages 59 - 69 ISSN 0364-7722 Altmetric
2019	Cannabidiol improves behavioural and neurochemical deficits in adult female offspring of the maternal immune activation (poly I:C) model of neurodevelopmental disorders Published In Brain, Behavior, and Immunity Volume 81 Pages 574 - 587 ISSN 0889-1591 Altmetric
2019	Effect of cannabidiol on endocannabinoid, glutamatergic and GABAergic signalling markers in male offspring of a maternal immune activation (poly I:C) model relevant to schizophrenia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 95 Pages 109666-1 - 109666-10 ISSN 0364-7722 Altmetric
2019	Effects of antipsychotic drugs on neurites relevant to schizophrenia treatment Published In Medicinal Research Reviews Volume 39 Pages 386 - 403 ISSN 0198-6325 Altmetric
2019	Increased translocator protein (TSPO) binding throughout neurodevelopment in the perinatal phencyclidine rodent model of schizophrenia Published In Schizophrenia Research Volume 212 Pages 243 - 245 ISSN 0920-9964 Altmetric
2019	Nano-sunscreens – a double-edged sword in protecting consumers from harm: viewing Australian regulatory policies through the lenses of the European Union Published In Critical Reviews in Toxicology Volume Online First Pages 1 - 18 ISSN 1040-8444 Altmetric
2019	Olanzapine-induced endoplasmic reticulum stress and inflammation in the hypothalamus were inhibited by an ER stress inhibitor 4-phenylbutyrate Published In Psychoneuroendocrinology Volume 104 Pages 286 - 299 ISSN 0306-4530 Altmetric
2019	Patients with drug-naive bipolar disorder in remission after 8 weeks of treatment had decreased serum uric acid concentrations Published In Frontiers in Psychiatry Volume 10 Pages 767-1 - 767-8 ISSN 1664-0640 Altmetric
2019	Risperidone stimulates food intake and induces body weight gain via the hypothalamic arcuate nucleus 5-HT2c receptor—NPY pathway Published In CNS Neuroscience and Therapeutics Pages 1 - 9 Altmetric
2019	Sensitivity of plasma cholecystokinin and peptide YY in obese and normal weight men Published In Malaysian Journal of Nutrition Volume 25 Pages 217 - 226 Altmetric
2019	Tacrine-Hydrogen Sulfide Donor Hybrid Ameliorates Cognitive Impairment in the Aluminum Chloride Mouse Model of Alzheimer's Disease Published In ACS Chemical Neuroscience Volume 10 Pages 3500 - 3509 ISSN 1948-7193 Altmetric
2018	3D imaging of PSD-95 in the mouse brain using the advanced CUBIC method Published In Molecular Brain Volume 11 Pages 50-1 - 50-4 ISSN 1756-6606 Altmetric
2018	A postmortem analysis of NMDA ionotropic and group 1 metabotropic glutamate receptors in the nucleus accumbens in schizophrenia Published In Journal of Psychiatry and Neuroscience Volume 43 Pages 102 - 110 ISSN 0702-8466 Altmetric
2018	Association between hyperuricemia and metabolic syndrome in patients suffering from bipolar disorder Published In BMC Psychiatry Volume 18 Pages 390-1 - 390-7 ISSN 1471-244X Altmetric
2018	Changes in metabolism and microbiota after 24-week risperidone treatment in drug naïve, normal weight patients with first episode schizophrenia Published In Schizophrenia Research Volume 201 Pages 299 - 306 ISSN 0920-9964 Altmetric
2018	Chronic Adolescent CDPPB Treatment Alters Short-Term, but not Long-Term, Glutamatergic Receptor Expression Published In Neurochemical Research Volume 43 Pages 1 - 9 ISSN 0364-3190 Altmetric
2018	Cold exposure promotes obesity and impairs glucose homeostasis in mice subjected to a highfat diet Published In Molecular Medicine Reports Volume 18 Pages 3923 - 3931 Altmetric
2018	Commentary: GLYX-13 Ameliorates Schizophrenia-Like Phenotype Induced by MK-801 in Mice: Role of Hippocampal NR2B and DISC1 Published In Frontiers in Molecular Neuroscience Volume 11 Pages 315-1 - 315-3 ISSN 1662-5099 Altmetric
2018	Decreased 5‐HT2cR and GHSR1a interaction in antipsychotic drug‐induced obesity Published In Obesity Reviews Volume 19 Pages 396 - 405 ISSN 1467-7881 Altmetric
2018	Dietary Galacto-Oligosaccharides and Resistant Starch Protect Against Altered CB1 and 5-HT1A and 2A Receptor Densities in Rat Brain: Implications for Preventing Cognitive and Appetite Dysfunction During a High-Fat Diet Published In Molecular Nutrition and Food Research Volume 62 Pages 1800422-1 - 1800422-9 ISSN 1613-4125 Altmetric
2018	Disrupted sphingolipid metabolism following acute clozapine and olanzapine administration Published In British Journal of Biomedical Science Volume 25 Pages 40-1 - 40-11 ISSN 0967-4845 Altmetric
2018	Early antipsychotic treatment in juvenile rats elicits long-term alterations to the adult serotonin receptors Published In Neuropsychiatric Disease and Treatment Volume 14 Pages 1569 - 1583 ISSN 1176-6328 Altmetric
2018	Effect of multi-walled carbon nanotubes on the cross-linking density of the poly(glycerol sebacate) elastomeric nanocomposites Published In Journal of Colloid and Interface Science Volume 521 Pages 24 - 32 ISSN 0021-9797 Altmetric
2018	Effects of short- and long-term aripiprazole treatment on Group I mGluRs in the nucleus accumbens: Comparison with haloperidol Published In Psychiatry Research Volume 260 Pages 152 - 157 ISSN 1872-7123 Altmetric
2018	Electrical Stimulation with a Conductive Polymer Promotes Neurite Outgrowth and Synaptogenesis in Primary Cortical Neurons in 3D Published In Scientific Reports Volume 8 Pages 9855-1 - 9855-10 ISSN 2045-2322 Altmetric
2018	Galantamine improves cognition, hippocampal inflammation, and synaptic plasticity impairments induced by lipopolysaccharide in mice Published In Journal of Neuroinflammation Volume 15 Pages 112-1 - 112-15 ISSN 1742-2094 Altmetric
2018	Ginsenoside Rb1 improves leptin sensitivity in the prefrontal cortex in obese mice Published In CNS Neuroscience and Therapeutics Volume 24 Pages 98 - 107 ISSN 1755-5949 Altmetric
2018	Liraglutide prevents metabolic side-effects and improves recognition and working memory during antipsychotic treatment in rats Published In Journal of Psychopharmacology Volume 32 Pages 578 - 590 ISSN 0269-8811 Altmetric
2018	Microglia activation in the offspring of prenatal Poly I: C exposed rats: a PET imaging and immunohistochemistry study Published In General Psychiatry Volume 31 Pages e000006-1 - e000006-36 Altmetric
2018	Obesity, altered oxidative stress, and clinical correlates in chronic schizophrenia patients Published In Translational Psychiatry Volume 8 Page p. 258 ISSN 2158-3188 Altmetric
2018	Perinatal administration of phencyclidine alters expression of Lingo-1 signaling pathway proteins in the prefrontal cortex of juvenile and adult rats Published In Neuronal Signaling Volume 2 Pages 1 - 12 Altmetric
2018	Propionate protects haloperidol-induced neurite lesions mediated by neuropeptide Y Published In Frontiers in Neuroscience Volume 12 Pages 743-1 - 743-10 ISSN 1662-4548 Altmetric
2018	RANKL reduces body weight and food intake via the modulation of hypothalamic NPY/CART expression Published In International Journal of Medical Sciences Volume 15 Pages 969 - 977 ISSN 1449-1907 Altmetric
2018	Serum NCAM levels and cognitive deficits in first episode schizophrenia patients versus health controls Published In Schizophrenia Research Volume 192 Pages 457 - 458 ISSN 0920-9964 Altmetric
2017	Alterations of ubiquitin related proteins in the pathology and development of schizophrenia: Evidence from human and animal studies Published In Journal of Psychiatric Research Volume 90 Pages 31 - 39 ISSN 0022-3956 Altmetric
2017	Association between DBH 19 bp insertion/deletion polymorphism and cognition in schizophrenia with and without tardive dyskinesia Published In Schizophrenia Research Volume 182 Pages 104 - 109 ISSN 0920-9964 Altmetric
2017	Cannabidiol rescues glutamatergic, memory and social interaction deficits following prenatal infection: a follow-up in female offspring Published In European Neuropsychopharmacology Volume 27 Pages S890 - S890 ISSN 0924-977X Altmetric
2017	Current views on neuropeptide Y and diabetes-related atherosclerosis Published In Diabetes and Vascular Disease Research Volume 14 Pages 277 - 284 ISSN 1479-1641 Altmetric
2017	Dietary teasaponin ameliorates alteration of gut microbiota and cognitive decline in diet-induced obese mice Published In Scientific Reports Volume 7 Pages 12203 -1 - 12203 -13 ISSN 2045-2322 Altmetric
2017	Electrical stimulation using conductive polymer polypyrrole counters reduced neurite outgrowth of primary prefrontal cortical neurons from NRG1-KO and DISC1-LI mice Published In Scientific Reports Volume 7 Pages 42525 -1 - 42525 -8 ISSN 2045-2322 Altmetric
2017	Gender differences measured by the MATRICS consensus cognitive battery in chronic schizophrenia patients Published In Scientific Reports Volume 7 Pages 11821-1 - 11821-8 ISSN 2045-2322 Altmetric
2017	Improved social interaction, recognition and working memory with cannabidiol treatment in a prenatal infection (poly I:C) rat model Published In Neuropsychopharmacology Volume 42 Pages 1447 - 1457 ISSN 0893-133X Altmetric
2017	Intake of 7,8-dihydroxyflavone from pregnancy to weaning prevents cognitive deficits in adult offspring after maternal immune activation Published In European Archives of Psychiatry and Clinical Neuroscience: official organ of the German society for biological psychiatry Volume 267 Pages 479 - 483 ISSN 0940-1334 Altmetric
2017	Luteolin, a natural flavonoid, inhibits methylglyoxal induced apoptosis via the mTOR/4E-BP1 signaling pathway Published In Scientific Reports Volume 7 Pages 7877-1 - 7877-11 ISSN 2045-2322 Altmetric
2017	Molecular mechanisms of antipsychotic drug-induced diabetes Published In Frontiers in Neuroscience Volume 11 Pages 643-1 - 643-12 ISSN 1662-4548 Altmetric
2017	Prevalence and correlates of psychological distress among diabetes mellitus adults in the Jilin province in China: a cross-sectional study Published In PEERJ Volume 5 Pages e2869-1 - e2869-17 Altmetric
2017	Probe Sensor Using Nanostructured Multi-Walled Carbon Nanotube Yarn for Selective and Sensitive Detection of Dopamine Published In Sensors Volume 17 Pages 884-1 - 884-9 ISSN 1424-8220 Altmetric
2017	Reduced serum levels of oestradiol and brain derived neurotrophic factor in both diabetic women and HFD-feeding female mice Published In Endocrine Volume 56 Pages 65 - 72 ISSN 1355-008X Altmetric
2017	Tailoring the wettability and mechanical properties of electrospun poly(L-lactic acid)-poly(glycerol sebacate) core-shell membranes for biomedical applications Published In Journal of Colloid and Interface Science Volume 508 Pages 87 - 94 ISSN 0021-9797 Altmetric
2017	The central mechanism of risperidone-induced hyperprolactinemia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 76 Pages 134 - 139 ISSN 0364-7722 Altmetric
2017	Time-dependent changes and potential mechanisms of glucose-lipid metabolic disorders associated with chronic clozapine or olanzapine treatment in rats Published In Scientific Reports Volume 7 Pages 2762-1 - 2762-13 ISSN 2045-2322 Altmetric
2017	Time-dependent effects of olanzapine treatment on the expression of histidine decarboxylase, H1 and H3 receptor in the rat brain: The roles in olanzapine-induced obesity Published In Psychoneuroendocrinology Volume 85 Pages 190 - 199 ISSN 0306-4530 Altmetric
2016	A label-free and high-throughput separation of neuron and glial cells using an inertial microfluidic platform Published In Biomicrofluidics Volume 10 Pages 034104-1 - 034104-12 ISSN 1932-1058 Altmetric
2016	A splicing-regulatory polymorphism in DRD2 disrupts ZRANB2 binding, impairs cognitive functioning and increases risk for schizophrenia in six Han Chinese samples Published In Molecular Psychiatry Volume 21 Pages 975 - 982 ISSN 1359-4184 Altmetric
2016	Ameliorating antipsychotic-induced weight gain by betahistine: mechanisms and clinical implications Published In Pharmacological Research Volume 106 Pages 51 - 63 ISSN 1043-6618 Altmetric
2016	Aripiprazole and haloperidol activate GSK3β-dependent signalling pathway differentially in various brain regions of rats Published In International Journal of Molecular Sciences Volume 17 Pages 459-1 - 459-11 ISSN 1422-0067 Altmetric
2016	Aripiprazole increases the PKA signalling and expression of the GABA_A receptor and CREB1 in the nucleus accumbens of rats Published In Journal of Molecular Neuroscience Volume 59 Pages 36 - 47 ISSN 0895-8696 Altmetric
2016	Association between DβH5′ insertion/deletion polymorphism and cognition in patients with chronic schizophrenia Published In Journal of Clinical Psychiatry Volume 77 Pages 379 - 385 ISSN 1096-0104 Altmetric
2016	Bardoxolone methyl prevents high-fat diet-induced colon inflammation in mice Published In Journal of Histochemistry and Cytochemistry: imaging the spectrum of cell biology Volume 64 Pages 237 - 255 ISSN 0022-1554 Altmetric
2016	Bardoxolone methyl prevents obesity and hypothalamic dysfunction Published In Chemico-Biological Interactions Volume 256 Pages 178 - 187 ISSN 0009-2797 Altmetric
2016	Chlorogenic acid protects d-galactose-induced liver and kidney injury via antioxidation and anti-inflammation effects in mice Published In Pharmaceutical Biology Volume 54 Pages 1027 - 1034 ISSN 1744-5116 Altmetric
2016	Chronic administration of aripiprazole activates GSK3β-dependent signalling pathways, and up-regulates GABA_A receptor expression and CREB1 activity in rats Published In Scientific Reports Volume 6 Pages 30040-1 - 30040-12 ISSN 2045-2322 Altmetric
2016	Chronic rhein treatment improves recognition memory in high-fat diet-induced obese male mice Published In Journal of Nutritional Biochemistry Volume 36 Pages 42 - 50 ISSN 0955-2863 Altmetric
2016	Early antipsychotic treatment in childhood/adolescent period has long-term effects on depressive-like, anxiety-like and locomotor behaviours in adult rats Published In Journal of Psychopharmacology Volume 30 Pages 204 - 214 ISSN 0269-8811 Altmetric
2016	Early antipsychotic treatment in juvenile rats elicits long-term alterations to the dopamine neurotransmitter system Published In International Journal of Molecular Sciences Volume 17 Pages 1944-1 - 1944-20 ISSN 1422-0067 Altmetric
2016	Effect of a glucagon-like peptide 1 (GLP-1) receptor agonist, liraglutide, on cognition and body weight during antipsychotic treatment Published In International Journal of Neuropsychopharmacology Volume 19 Pages 55 - 55 ISSN 1461-1457 Altmetric
2016	Effect of cannabidiol on cognition in a maternal immune activation (poly IC) model of schizophrenia Published In International Journal of Neuropsychopharmacology Volume 19 Pages 183 - 183 ISSN 1461-1457 Altmetric
2016	Intake of 7,8-dihydroxyflavone during juvenile and adolescent stages prevents onset of psychosis in adult offspring after maternal immune activation Published In Scientific Reports Volume 6 Pages 36087-1 - 36087-10 ISSN 2045-2322 Altmetric
2016	Interaction of BDNF with cytokines in chronic schizophrenia Published In Brain, Behavior, and Immunity Volume 51 Pages 169 - 175 ISSN 0889-1591 Altmetric
2016	Neurodevelopmental expression profile of dimeric and monomeric group 1 mGluRs: relevance to schizophrenia pathogenesis and treatment Published In Scientific Reports Volume 6 Pages 34391-1 - 34391-10 ISSN 2045-2322 Altmetric
2016	Olanzapine prevents the PCP-induced reduction in the neurite outgrowth of prefrontal cortical neurons via NRG1 Published In Scientific Reports Volume 6 Pages 19581-1 - 19581-11 ISSN 2045-2322 Altmetric
2016	Protective effect of the orientin on noise-induced cognitive impairments in mice Published In Behavioural Brain Research Volume 296 Pages 290 - 300 ISSN 0166-4328 Altmetric
2016	Reversal effect of simvastatin on the decrease in cannabinoid receptor 1 density in 6-hydroxydopamine lesioned rat brains Published In Life Sciences Volume 155 Pages 123 - 132 ISSN 0024-3205 Altmetric
2016	Selective binding modes and allosteric inhibitory effects of lupane triterpenes on protein tyrosine phosphatase 1B Published In Scientific Reports Volume 6 Pages 20766-1 - 20766-14 ISSN 2045-2322 Altmetric
2016	Smoking and serum lipid profiles in schizophrenia Published In Neuroscience Bulletin Volume 32 Pages 383 - 388 ISSN 1673-7067 Altmetric
2016	The Neurodevelopmental Profile of Group 1 Metabotropic Glutamate Receptors: Implications for Novel Therapeutics Published In International Journal of Neuropsychopharmacology Volume 19 Pages 78 - 79 ISSN 1461-1457 Altmetric
2016	Use of conducting polymers to facilitate neurite branching in schizophrenia-related neuronal development Published In Biomaterials Science Volume 4 Pages 1244 - 1251 ISSN 2047-4849 Altmetric
2016	mGluR2/3 agonist LY379268 rescues NMDA and GABAA receptor level deficits induced in a two-hit mouse model of schizophrenia Published In Psychopharmacology Volume 233 Pages 1349 - 1359 ISSN 0033-3158 Altmetric
2015	Alterations of mGluR5 and its endogenous regulators Norbin, Tamalin and Preso1 in schizophrenia: towards a model of mGluR5 dysregulation Published In Acta Neuropathologica Volume 130 Pages 119 - 129 ISSN 0001-6322 Altmetric
2015	Alterations of p75 neurotrophin receptor and Myelin transcription factor 1 in the hippocampus of perinatal phencyclidine treated rats Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 63 Pages 91 - 97 ISSN 0364-7722 Altmetric

Investigator On

Year	Title
2017 - 2021	Australian Centre for Cannabinoid Clinical and Research Excellence (ACRE): Quality and safety in the implementation of medicinal cannabis use in the community Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Centres of Research Excellence
2020	Neurite deficits, obesity and cortical thinning: Prevention and treatment in schizophrenia Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Investigator Grants
2019	GoBlot machines and Leica Objective Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2019	Rat activity wheel and living chamber system Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2019	The influence of diet on the microbiome and the subsequent manifestation of metabolic disease including non-alcoholic fatty liver disease Awarded by: NUW Alliance Funding Scheme: Grant
2019	Volumetric Imaging Facility: Observing the Cell in its Native Environment Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2018	Forced exercise/walking wheel system for rats Model 80805A Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2017	Lumenera Infinity 2-5 microscope colour camera Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2014 - 2017	Application of intelligent conducting polymers for treating schizophrenia and allied disorders focusing on neuronal outgrowth, myelination and synaptogenesis Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2012 - 2016	Schizophrenia: reversal of antipsychotic drug-induced obesity and its related metabolic disorders Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2014	Regional flow cytometry facility Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2014	SR-LAB ABS System Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2013	Neon Transfection System: Workstation for transfer of genetic material into hard-to-work-with cells Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2013	Roles of muscarinic M3 receptors in antipsychotic-induced metabolic side-effects: prevention and treatment of anti-psychotic insulin dysregulation Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2012	How do distinct fatty acids affect central leptin sensitivity and glucose intolerance in obesity and Type II diabetes? Awarded by: Diabetes Australia Funding Scheme: Research Grant
2012	Integrated facility for confocal imaging and single molecule flourescence analysis Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2012	Investigating the interaction between inflammation, obesity and colon cancer Awarded by: Australian Institute of Nuclear Science and Engineering (AINSE) Funding Scheme: Research Awards
2011	Eppendorf MasterCycler Pro thermocycler Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2011	In vitro gut fermentation system Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2011	The use of triterpene saponins from traditional medicinal herbs for improving leptin sensitivity and glucose intolerance in obesity and Type 2 diabetes Awarded by: Diabetes Australia Funding Scheme: Research Grant
2010	Precellys 24 tissue homogenizer and digital microplate shaker Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2010	Regional facility for molecular characterisation and mapping Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2010	Schizophrenia: prevention and treatment of atypical antipsychotic drug-induced obesity Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2009	Equipment for a molecular pathology laboratory Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2009	NMDA receptor/neuregulin 1 signalling in response to phencyclidine administration Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2009	Peripheral Benzodiazapine as an early Marker for Obesity and Inflammation: Implications for Development of Type II Diabetes Mellitus and Cancer Awarded by: Australian Institute of Nuclear Science and Engineering (AINSE) Funding Scheme: Research Award
2009	Unique state-of-the-art lipidomics infrastructure Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2008	Is a higher intake of omega-3 fatty acids advantageous for weight loss? Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2008	The role of cannabis in an Nrg 1 animal model of genetic vulnerability to schizophrenia Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2008	To obtain vital laboratory equipment dedicated to radioactive lab work and thus provide safer working conditions Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
	Contributions to Leica Dmi8 microscope Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
	Small animal stereotaxic instrument and microinjection unit Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant

Potential Supervision Topics

1. The mechanism of anti-psychotic drug action for schizophrenia;
2. Neural branching repair for a better neural connectivity and networking;
3. How to use flowcytometry and cell imaging skills to study pathological based cells

Advisees

Graduate Advising Relationship

Degree	Research Title	Advisee
Doctor of Philosophy (Integrated)	The Role of DISC1 on regulating neurite outgrowth through mediating signalling pathway induced by D2/D1 receptor activation in the Prefrontal cortical Neurons	Zheng, Peng
Doctor of Philosophy	The role of olanzapine-induced autophagy in the hypothalamic energy regulatory pathwsay	Boz, Zehra
Doctor of Philosophy (Integrated)	The role of D2R and NR2B interaction in neurite regulation	Xie, Yuanyi
Doctor of Philosophy	Development of Innovative Functionalized Colored NanoMaterials in Lateral Flow Biosensor Applications for Disease-Related Biomarkers	Qin, Chunyan
Doctor of Philosophy	Prevention of brain inflammation affecting neural connectivity in schizophrenia	Dongol, Anjila
Doctor of Philosophy	Advanced nanoceramic composite for health protection applications.	Rehman, Yaser
Doctor of Philosophy	The influence of dietary fibre intake on the gut microbiota and the implication for metabolic disease	Williams, Georgina
Doctor of Philosophy (Integrated)	The Molecular Mechanism of Microbiota-Gut-Brain Axis Influenced by Dietary Fibre Types	Wang, Zhizhen
Master of Philosophy -SMAH	Assessment of a novel therapeutic drug to protect neural impairment and prevent cognitive decline in type 2 diabetes	Chen, Xi
Doctor of Philosophy	Investigation of the kynurenine pathway in major depression	Brown, Samara
Doctor of Philosophy	The effect of different beneficial compounds from the cannabis plant on psychotic and cognitive behaviours and the underlying mechanisms	Jimenez Naranjo, Carlos

Education And Training

Ph.D. in Neuropharmacology, University of Wollongong, School of Medicine, Neural connectivity 2018 -

Orcid Id

http://orcid.org/0000-0002-5895-2253 (confirmed)

Web Of Science Researcher Id

H-7408-2015

Scopus Id

12762323800" title="Scopus ID Link" target="_blank">12762323800

Top Publications

Year	Title
2009	The Rhesus Monkey Brain in Stereotaxic Coordinates
2016	A label-free and high-throughput separation of neuron and glial cells using an inertial microfluidic platform Published in Biomicrofluidics
2017	Electrical stimulation using conductive polymer polypyrrole counters reduced neurite outgrowth of primary prefrontal cortical neurons from NRG1-KO and DISC1-LI mice Published in Scientific Reports
2017	Intake of 7,8-dihydroxyflavone from pregnancy to weaning prevents cognitive deficits in adult offspring after maternal immune activation Published in European Archives of Psychiatry and Clinical Neuroscience: official organ of the German society for biological psychiatry
2017	Probe Sensor Using Nanostructured Multi-Walled Carbon Nanotube Yarn for Selective and Sensitive Detection of Dopamine Published in Sensors

Research Areas

Research Overview

He has published 224 articles, which has been cited 7,145 times. In addition, his books have been cited 1,105 times. He has had 38 publications in the top 5%, and 79 publications in the top 10% most cited publications worldwide (UOW Library Report, 2016). From his research publications, there are 14 research articles cited more than 100 times, and 41 articles with more than 50 citations. In the past three years, he has had an average of over 500 citations per year, with a recent increased trajectory. He has an H-index of 46 (Google Scholar 2016).

Collaborations: He has an extensive collaboration network with world leading research laboratories both nationally and internationally. This enables him to access advanced knowledge, skills, equipment, and databases, to receive international and industry research funding, and to attract highly talented HDR students and postdoctoral research fellows.

Supervision and mentoring of Postdoctoral Fellows and Postgraduate Students: He has successfully mentored postgraduate completions comprising 12 PhD and 4 Masters students, as well as 4 Honours students in the last 5 years. Over his research career, He has mentored 14 postdoctoral fellows, 8 international visiting fellows and 6 research assistants. He received the University of Wollongong Vice Chancellor’s Excellence in Research Supervision Award in 2010.

Contribution to NHMRC, ARC and Peer review involvement: He has been an external assessor reviewing various project grants including for NHMRC from 1997 to present, IHMRI from 2012 to 2015, Schizophrenia Research Institute from 2010 to 2015, Medical Research Commercialisation Fund from 2012 to 2013, ARC Future Fellowship in 2012 and Diabetes Australia 2011-2013. He is Editorial Board Member for Frontier Neuroscience, International J of Obesity, Basic Sciences of Medicine, and a reviewer for more than 20 leading international referred journals.

Geographic Focus

Australia Country

Selected Publications

Journal Article

Year	Title
2019	Alterations to the microbiota–colon–brain axis in high-fat-diet-induced obese mice compared to diet-resistant mice Published In Journal of Nutritional Biochemistry Volume 65 Pages 54 - 65 ISSN 0955-2863 Altmetric
2019	An alternating least square based algorithm for predicting patient survivability Published In Communications in Computer and Information Science Volume 996 Pages 305 - 317 Altmetric
2019	Aripiprazole and haloperidol protect neurite lesions via reducing excessive D2R-DISC1 complex formation Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 92 Pages 59 - 69 ISSN 0364-7722 Altmetric
2019	Cannabidiol improves behavioural and neurochemical deficits in adult female offspring of the maternal immune activation (poly I:C) model of neurodevelopmental disorders Published In Brain, Behavior, and Immunity Volume 81 Pages 574 - 587 ISSN 0889-1591 Altmetric
2019	Effect of cannabidiol on endocannabinoid, glutamatergic and GABAergic signalling markers in male offspring of a maternal immune activation (poly I:C) model relevant to schizophrenia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 95 Pages 109666-1 - 109666-10 ISSN 0364-7722 Altmetric
2019	Effects of antipsychotic drugs on neurites relevant to schizophrenia treatment Published In Medicinal Research Reviews Volume 39 Pages 386 - 403 ISSN 0198-6325 Altmetric
2019	Increased translocator protein (TSPO) binding throughout neurodevelopment in the perinatal phencyclidine rodent model of schizophrenia Published In Schizophrenia Research Volume 212 Pages 243 - 245 ISSN 0920-9964 Altmetric
2019	Nano-sunscreens – a double-edged sword in protecting consumers from harm: viewing Australian regulatory policies through the lenses of the European Union Published In Critical Reviews in Toxicology Volume Online First Pages 1 - 18 ISSN 1040-8444 Altmetric
2019	Olanzapine-induced endoplasmic reticulum stress and inflammation in the hypothalamus were inhibited by an ER stress inhibitor 4-phenylbutyrate Published In Psychoneuroendocrinology Volume 104 Pages 286 - 299 ISSN 0306-4530 Altmetric
2019	Patients with drug-naive bipolar disorder in remission after 8 weeks of treatment had decreased serum uric acid concentrations Published In Frontiers in Psychiatry Volume 10 Pages 767-1 - 767-8 ISSN 1664-0640 Altmetric
2019	Risperidone stimulates food intake and induces body weight gain via the hypothalamic arcuate nucleus 5-HT2c receptor—NPY pathway Published In CNS Neuroscience and Therapeutics Pages 1 - 9 Altmetric
2019	Sensitivity of plasma cholecystokinin and peptide YY in obese and normal weight men Published In Malaysian Journal of Nutrition Volume 25 Pages 217 - 226 Altmetric
2019	Tacrine-Hydrogen Sulfide Donor Hybrid Ameliorates Cognitive Impairment in the Aluminum Chloride Mouse Model of Alzheimer's Disease Published In ACS Chemical Neuroscience Volume 10 Pages 3500 - 3509 ISSN 1948-7193 Altmetric
2018	3D imaging of PSD-95 in the mouse brain using the advanced CUBIC method Published In Molecular Brain Volume 11 Pages 50-1 - 50-4 ISSN 1756-6606 Altmetric
2018	A postmortem analysis of NMDA ionotropic and group 1 metabotropic glutamate receptors in the nucleus accumbens in schizophrenia Published In Journal of Psychiatry and Neuroscience Volume 43 Pages 102 - 110 ISSN 0702-8466 Altmetric
2018	Association between hyperuricemia and metabolic syndrome in patients suffering from bipolar disorder Published In BMC Psychiatry Volume 18 Pages 390-1 - 390-7 ISSN 1471-244X Altmetric
2018	Changes in metabolism and microbiota after 24-week risperidone treatment in drug naïve, normal weight patients with first episode schizophrenia Published In Schizophrenia Research Volume 201 Pages 299 - 306 ISSN 0920-9964 Altmetric
2018	Chronic Adolescent CDPPB Treatment Alters Short-Term, but not Long-Term, Glutamatergic Receptor Expression Published In Neurochemical Research Volume 43 Pages 1 - 9 ISSN 0364-3190 Altmetric
2018	Cold exposure promotes obesity and impairs glucose homeostasis in mice subjected to a highfat diet Published In Molecular Medicine Reports Volume 18 Pages 3923 - 3931 Altmetric
2018	Commentary: GLYX-13 Ameliorates Schizophrenia-Like Phenotype Induced by MK-801 in Mice: Role of Hippocampal NR2B and DISC1 Published In Frontiers in Molecular Neuroscience Volume 11 Pages 315-1 - 315-3 ISSN 1662-5099 Altmetric
2018	Decreased 5‐HT2cR and GHSR1a interaction in antipsychotic drug‐induced obesity Published In Obesity Reviews Volume 19 Pages 396 - 405 ISSN 1467-7881 Altmetric
2018	Dietary Galacto-Oligosaccharides and Resistant Starch Protect Against Altered CB1 and 5-HT1A and 2A Receptor Densities in Rat Brain: Implications for Preventing Cognitive and Appetite Dysfunction During a High-Fat Diet Published In Molecular Nutrition and Food Research Volume 62 Pages 1800422-1 - 1800422-9 ISSN 1613-4125 Altmetric
2018	Disrupted sphingolipid metabolism following acute clozapine and olanzapine administration Published In British Journal of Biomedical Science Volume 25 Pages 40-1 - 40-11 ISSN 0967-4845 Altmetric
2018	Early antipsychotic treatment in juvenile rats elicits long-term alterations to the adult serotonin receptors Published In Neuropsychiatric Disease and Treatment Volume 14 Pages 1569 - 1583 ISSN 1176-6328 Altmetric
2018	Effect of multi-walled carbon nanotubes on the cross-linking density of the poly(glycerol sebacate) elastomeric nanocomposites Published In Journal of Colloid and Interface Science Volume 521 Pages 24 - 32 ISSN 0021-9797 Altmetric
2018	Effects of short- and long-term aripiprazole treatment on Group I mGluRs in the nucleus accumbens: Comparison with haloperidol Published In Psychiatry Research Volume 260 Pages 152 - 157 ISSN 1872-7123 Altmetric
2018	Electrical Stimulation with a Conductive Polymer Promotes Neurite Outgrowth and Synaptogenesis in Primary Cortical Neurons in 3D Published In Scientific Reports Volume 8 Pages 9855-1 - 9855-10 ISSN 2045-2322 Altmetric
2018	Galantamine improves cognition, hippocampal inflammation, and synaptic plasticity impairments induced by lipopolysaccharide in mice Published In Journal of Neuroinflammation Volume 15 Pages 112-1 - 112-15 ISSN 1742-2094 Altmetric
2018	Ginsenoside Rb1 improves leptin sensitivity in the prefrontal cortex in obese mice Published In CNS Neuroscience and Therapeutics Volume 24 Pages 98 - 107 ISSN 1755-5949 Altmetric
2018	Liraglutide prevents metabolic side-effects and improves recognition and working memory during antipsychotic treatment in rats Published In Journal of Psychopharmacology Volume 32 Pages 578 - 590 ISSN 0269-8811 Altmetric
2018	Microglia activation in the offspring of prenatal Poly I: C exposed rats: a PET imaging and immunohistochemistry study Published In General Psychiatry Volume 31 Pages e000006-1 - e000006-36 Altmetric
2018	Obesity, altered oxidative stress, and clinical correlates in chronic schizophrenia patients Published In Translational Psychiatry Volume 8 Page p. 258 ISSN 2158-3188 Altmetric
2018	Perinatal administration of phencyclidine alters expression of Lingo-1 signaling pathway proteins in the prefrontal cortex of juvenile and adult rats Published In Neuronal Signaling Volume 2 Pages 1 - 12 Altmetric
2018	Propionate protects haloperidol-induced neurite lesions mediated by neuropeptide Y Published In Frontiers in Neuroscience Volume 12 Pages 743-1 - 743-10 ISSN 1662-4548 Altmetric
2018	RANKL reduces body weight and food intake via the modulation of hypothalamic NPY/CART expression Published In International Journal of Medical Sciences Volume 15 Pages 969 - 977 ISSN 1449-1907 Altmetric
2018	Serum NCAM levels and cognitive deficits in first episode schizophrenia patients versus health controls Published In Schizophrenia Research Volume 192 Pages 457 - 458 ISSN 0920-9964 Altmetric
2017	Alterations of ubiquitin related proteins in the pathology and development of schizophrenia: Evidence from human and animal studies Published In Journal of Psychiatric Research Volume 90 Pages 31 - 39 ISSN 0022-3956 Altmetric
2017	Association between DBH 19 bp insertion/deletion polymorphism and cognition in schizophrenia with and without tardive dyskinesia Published In Schizophrenia Research Volume 182 Pages 104 - 109 ISSN 0920-9964 Altmetric
2017	Cannabidiol rescues glutamatergic, memory and social interaction deficits following prenatal infection: a follow-up in female offspring Published In European Neuropsychopharmacology Volume 27 Pages S890 - S890 ISSN 0924-977X Altmetric
2017	Current views on neuropeptide Y and diabetes-related atherosclerosis Published In Diabetes and Vascular Disease Research Volume 14 Pages 277 - 284 ISSN 1479-1641 Altmetric
2017	Dietary teasaponin ameliorates alteration of gut microbiota and cognitive decline in diet-induced obese mice Published In Scientific Reports Volume 7 Pages 12203 -1 - 12203 -13 ISSN 2045-2322 Altmetric
2017	Electrical stimulation using conductive polymer polypyrrole counters reduced neurite outgrowth of primary prefrontal cortical neurons from NRG1-KO and DISC1-LI mice Published In Scientific Reports Volume 7 Pages 42525 -1 - 42525 -8 ISSN 2045-2322 Altmetric
2017	Gender differences measured by the MATRICS consensus cognitive battery in chronic schizophrenia patients Published In Scientific Reports Volume 7 Pages 11821-1 - 11821-8 ISSN 2045-2322 Altmetric
2017	Improved social interaction, recognition and working memory with cannabidiol treatment in a prenatal infection (poly I:C) rat model Published In Neuropsychopharmacology Volume 42 Pages 1447 - 1457 ISSN 0893-133X Altmetric
2017	Intake of 7,8-dihydroxyflavone from pregnancy to weaning prevents cognitive deficits in adult offspring after maternal immune activation Published In European Archives of Psychiatry and Clinical Neuroscience: official organ of the German society for biological psychiatry Volume 267 Pages 479 - 483 ISSN 0940-1334 Altmetric
2017	Luteolin, a natural flavonoid, inhibits methylglyoxal induced apoptosis via the mTOR/4E-BP1 signaling pathway Published In Scientific Reports Volume 7 Pages 7877-1 - 7877-11 ISSN 2045-2322 Altmetric
2017	Molecular mechanisms of antipsychotic drug-induced diabetes Published In Frontiers in Neuroscience Volume 11 Pages 643-1 - 643-12 ISSN 1662-4548 Altmetric
2017	Prevalence and correlates of psychological distress among diabetes mellitus adults in the Jilin province in China: a cross-sectional study Published In PEERJ Volume 5 Pages e2869-1 - e2869-17 Altmetric
2017	Probe Sensor Using Nanostructured Multi-Walled Carbon Nanotube Yarn for Selective and Sensitive Detection of Dopamine Published In Sensors Volume 17 Pages 884-1 - 884-9 ISSN 1424-8220 Altmetric
2017	Reduced serum levels of oestradiol and brain derived neurotrophic factor in both diabetic women and HFD-feeding female mice Published In Endocrine Volume 56 Pages 65 - 72 ISSN 1355-008X Altmetric
2017	Tailoring the wettability and mechanical properties of electrospun poly(L-lactic acid)-poly(glycerol sebacate) core-shell membranes for biomedical applications Published In Journal of Colloid and Interface Science Volume 508 Pages 87 - 94 ISSN 0021-9797 Altmetric
2017	The central mechanism of risperidone-induced hyperprolactinemia Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 76 Pages 134 - 139 ISSN 0364-7722 Altmetric
2017	Time-dependent changes and potential mechanisms of glucose-lipid metabolic disorders associated with chronic clozapine or olanzapine treatment in rats Published In Scientific Reports Volume 7 Pages 2762-1 - 2762-13 ISSN 2045-2322 Altmetric
2017	Time-dependent effects of olanzapine treatment on the expression of histidine decarboxylase, H1 and H3 receptor in the rat brain: The roles in olanzapine-induced obesity Published In Psychoneuroendocrinology Volume 85 Pages 190 - 199 ISSN 0306-4530 Altmetric
2016	A label-free and high-throughput separation of neuron and glial cells using an inertial microfluidic platform Published In Biomicrofluidics Volume 10 Pages 034104-1 - 034104-12 ISSN 1932-1058 Altmetric
2016	A splicing-regulatory polymorphism in DRD2 disrupts ZRANB2 binding, impairs cognitive functioning and increases risk for schizophrenia in six Han Chinese samples Published In Molecular Psychiatry Volume 21 Pages 975 - 982 ISSN 1359-4184 Altmetric
2016	Ameliorating antipsychotic-induced weight gain by betahistine: mechanisms and clinical implications Published In Pharmacological Research Volume 106 Pages 51 - 63 ISSN 1043-6618 Altmetric
2016	Aripiprazole and haloperidol activate GSK3β-dependent signalling pathway differentially in various brain regions of rats Published In International Journal of Molecular Sciences Volume 17 Pages 459-1 - 459-11 ISSN 1422-0067 Altmetric
2016	Aripiprazole increases the PKA signalling and expression of the GABA_A receptor and CREB1 in the nucleus accumbens of rats Published In Journal of Molecular Neuroscience Volume 59 Pages 36 - 47 ISSN 0895-8696 Altmetric
2016	Association between DβH5′ insertion/deletion polymorphism and cognition in patients with chronic schizophrenia Published In Journal of Clinical Psychiatry Volume 77 Pages 379 - 385 ISSN 1096-0104 Altmetric
2016	Bardoxolone methyl prevents high-fat diet-induced colon inflammation in mice Published In Journal of Histochemistry and Cytochemistry: imaging the spectrum of cell biology Volume 64 Pages 237 - 255 ISSN 0022-1554 Altmetric
2016	Bardoxolone methyl prevents obesity and hypothalamic dysfunction Published In Chemico-Biological Interactions Volume 256 Pages 178 - 187 ISSN 0009-2797 Altmetric
2016	Chlorogenic acid protects d-galactose-induced liver and kidney injury via antioxidation and anti-inflammation effects in mice Published In Pharmaceutical Biology Volume 54 Pages 1027 - 1034 ISSN 1744-5116 Altmetric
2016	Chronic administration of aripiprazole activates GSK3β-dependent signalling pathways, and up-regulates GABA_A receptor expression and CREB1 activity in rats Published In Scientific Reports Volume 6 Pages 30040-1 - 30040-12 ISSN 2045-2322 Altmetric
2016	Chronic rhein treatment improves recognition memory in high-fat diet-induced obese male mice Published In Journal of Nutritional Biochemistry Volume 36 Pages 42 - 50 ISSN 0955-2863 Altmetric
2016	Early antipsychotic treatment in childhood/adolescent period has long-term effects on depressive-like, anxiety-like and locomotor behaviours in adult rats Published In Journal of Psychopharmacology Volume 30 Pages 204 - 214 ISSN 0269-8811 Altmetric
2016	Early antipsychotic treatment in juvenile rats elicits long-term alterations to the dopamine neurotransmitter system Published In International Journal of Molecular Sciences Volume 17 Pages 1944-1 - 1944-20 ISSN 1422-0067 Altmetric
2016	Effect of a glucagon-like peptide 1 (GLP-1) receptor agonist, liraglutide, on cognition and body weight during antipsychotic treatment Published In International Journal of Neuropsychopharmacology Volume 19 Pages 55 - 55 ISSN 1461-1457 Altmetric
2016	Effect of cannabidiol on cognition in a maternal immune activation (poly IC) model of schizophrenia Published In International Journal of Neuropsychopharmacology Volume 19 Pages 183 - 183 ISSN 1461-1457 Altmetric
2016	Intake of 7,8-dihydroxyflavone during juvenile and adolescent stages prevents onset of psychosis in adult offspring after maternal immune activation Published In Scientific Reports Volume 6 Pages 36087-1 - 36087-10 ISSN 2045-2322 Altmetric
2016	Interaction of BDNF with cytokines in chronic schizophrenia Published In Brain, Behavior, and Immunity Volume 51 Pages 169 - 175 ISSN 0889-1591 Altmetric
2016	Neurodevelopmental expression profile of dimeric and monomeric group 1 mGluRs: relevance to schizophrenia pathogenesis and treatment Published In Scientific Reports Volume 6 Pages 34391-1 - 34391-10 ISSN 2045-2322 Altmetric
2016	Olanzapine prevents the PCP-induced reduction in the neurite outgrowth of prefrontal cortical neurons via NRG1 Published In Scientific Reports Volume 6 Pages 19581-1 - 19581-11 ISSN 2045-2322 Altmetric
2016	Protective effect of the orientin on noise-induced cognitive impairments in mice Published In Behavioural Brain Research Volume 296 Pages 290 - 300 ISSN 0166-4328 Altmetric
2016	Reversal effect of simvastatin on the decrease in cannabinoid receptor 1 density in 6-hydroxydopamine lesioned rat brains Published In Life Sciences Volume 155 Pages 123 - 132 ISSN 0024-3205 Altmetric
2016	Selective binding modes and allosteric inhibitory effects of lupane triterpenes on protein tyrosine phosphatase 1B Published In Scientific Reports Volume 6 Pages 20766-1 - 20766-14 ISSN 2045-2322 Altmetric
2016	Smoking and serum lipid profiles in schizophrenia Published In Neuroscience Bulletin Volume 32 Pages 383 - 388 ISSN 1673-7067 Altmetric
2016	The Neurodevelopmental Profile of Group 1 Metabotropic Glutamate Receptors: Implications for Novel Therapeutics Published In International Journal of Neuropsychopharmacology Volume 19 Pages 78 - 79 ISSN 1461-1457 Altmetric
2016	Use of conducting polymers to facilitate neurite branching in schizophrenia-related neuronal development Published In Biomaterials Science Volume 4 Pages 1244 - 1251 ISSN 2047-4849 Altmetric
2016	mGluR2/3 agonist LY379268 rescues NMDA and GABAA receptor level deficits induced in a two-hit mouse model of schizophrenia Published In Psychopharmacology Volume 233 Pages 1349 - 1359 ISSN 0033-3158 Altmetric
2015	Alterations of mGluR5 and its endogenous regulators Norbin, Tamalin and Preso1 in schizophrenia: towards a model of mGluR5 dysregulation Published In Acta Neuropathologica Volume 130 Pages 119 - 129 ISSN 0001-6322 Altmetric
2015	Alterations of p75 neurotrophin receptor and Myelin transcription factor 1 in the hippocampus of perinatal phencyclidine treated rats Published In Progress in Neuro-Psychopharmacology and Biological Psychiatry Volume 63 Pages 91 - 97 ISSN 0364-7722 Altmetric

Investigator On

Year	Title
2017 - 2021	Australian Centre for Cannabinoid Clinical and Research Excellence (ACRE): Quality and safety in the implementation of medicinal cannabis use in the community Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Centres of Research Excellence
2020	Neurite deficits, obesity and cortical thinning: Prevention and treatment in schizophrenia Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Investigator Grants
2019	GoBlot machines and Leica Objective Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2019	Rat activity wheel and living chamber system Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2019	The influence of diet on the microbiome and the subsequent manifestation of metabolic disease including non-alcoholic fatty liver disease Awarded by: NUW Alliance Funding Scheme: Grant
2019	Volumetric Imaging Facility: Observing the Cell in its Native Environment Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2018	Forced exercise/walking wheel system for rats Model 80805A Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2017	Lumenera Infinity 2-5 microscope colour camera Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2014 - 2017	Application of intelligent conducting polymers for treating schizophrenia and allied disorders focusing on neuronal outgrowth, myelination and synaptogenesis Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2012 - 2016	Schizophrenia: reversal of antipsychotic drug-induced obesity and its related metabolic disorders Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2014	Regional flow cytometry facility Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2014	SR-LAB ABS System Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2013	Neon Transfection System: Workstation for transfer of genetic material into hard-to-work-with cells Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2013	Roles of muscarinic M3 receptors in antipsychotic-induced metabolic side-effects: prevention and treatment of anti-psychotic insulin dysregulation Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2012	How do distinct fatty acids affect central leptin sensitivity and glucose intolerance in obesity and Type II diabetes? Awarded by: Diabetes Australia Funding Scheme: Research Grant
2012	Integrated facility for confocal imaging and single molecule flourescence analysis Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2012	Investigating the interaction between inflammation, obesity and colon cancer Awarded by: Australian Institute of Nuclear Science and Engineering (AINSE) Funding Scheme: Research Awards
2011	Eppendorf MasterCycler Pro thermocycler Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2011	In vitro gut fermentation system Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2011	The use of triterpene saponins from traditional medicinal herbs for improving leptin sensitivity and glucose intolerance in obesity and Type 2 diabetes Awarded by: Diabetes Australia Funding Scheme: Research Grant
2010	Precellys 24 tissue homogenizer and digital microplate shaker Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2010	Regional facility for molecular characterisation and mapping Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2010	Schizophrenia: prevention and treatment of atypical antipsychotic drug-induced obesity Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2009	Equipment for a molecular pathology laboratory Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
2009	NMDA receptor/neuregulin 1 signalling in response to phencyclidine administration Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2009	Peripheral Benzodiazapine as an early Marker for Obesity and Inflammation: Implications for Development of Type II Diabetes Mellitus and Cancer Awarded by: Australian Institute of Nuclear Science and Engineering (AINSE) Funding Scheme: Research Award
2009	Unique state-of-the-art lipidomics infrastructure Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2008	Is a higher intake of omega-3 fatty acids advantageous for weight loss? Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2008	The role of cannabis in an Nrg 1 animal model of genetic vulnerability to schizophrenia Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2008	To obtain vital laboratory equipment dedicated to radioactive lab work and thus provide safer working conditions Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
	Contributions to Leica Dmi8 microscope Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant
	Small animal stereotaxic instrument and microinjection unit Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Equipment Grant

Potential Supervision Topics

1. The mechanism of anti-psychotic drug action for schizophrenia;
2. Neural branching repair for a better neural connectivity and networking;
3. How to use flowcytometry and cell imaging skills to study pathological based cells

Advisees

Graduate Advising Relationship

Degree	Research Title	Advisee
Doctor of Philosophy (Integrated)	The Role of DISC1 on regulating neurite outgrowth through mediating signalling pathway induced by D2/D1 receptor activation in the Prefrontal cortical Neurons	Zheng, Peng
Doctor of Philosophy	The role of olanzapine-induced autophagy in the hypothalamic energy regulatory pathwsay	Boz, Zehra
Doctor of Philosophy (Integrated)	The role of D2R and NR2B interaction in neurite regulation	Xie, Yuanyi
Doctor of Philosophy	Development of Innovative Functionalized Colored NanoMaterials in Lateral Flow Biosensor Applications for Disease-Related Biomarkers	Qin, Chunyan
Doctor of Philosophy	Prevention of brain inflammation affecting neural connectivity in schizophrenia	Dongol, Anjila
Doctor of Philosophy	Advanced nanoceramic composite for health protection applications.	Rehman, Yaser
Doctor of Philosophy	The influence of dietary fibre intake on the gut microbiota and the implication for metabolic disease	Williams, Georgina
Doctor of Philosophy (Integrated)	The Molecular Mechanism of Microbiota-Gut-Brain Axis Influenced by Dietary Fibre Types	Wang, Zhizhen
Master of Philosophy -SMAH	Assessment of a novel therapeutic drug to protect neural impairment and prevent cognitive decline in type 2 diabetes	Chen, Xi
Doctor of Philosophy	Investigation of the kynurenine pathway in major depression	Brown, Samara
Doctor of Philosophy	The effect of different beneficial compounds from the cannabis plant on psychotic and cognitive behaviours and the underlying mechanisms	Jimenez Naranjo, Carlos

Education And Training

Ph.D. in Neuropharmacology, University of Wollongong, School of Medicine, Neural connectivity 2018 -

Orcid Id

http://orcid.org/0000-0002-5895-2253 (confirmed)

Web Of Science Researcher Id

H-7408-2015

Scopus Id

12762323800" title="Scopus ID Link" target="_blank">12762323800

Overview

Overview

Top Publications

Research Areas

Research Overview

Geographic Focus

Publications

Selected Publications

Journal Article

Funding

Investigator On

Supervision

Potential Supervision Topics

Advisees

Graduate Advising Relationship

Background

Education And Training

Identity

Orcid Id

Web Of Science Researcher Id

Scopus Id

Overview

Top Publications

Research Areas

Research Overview

Geographic Focus

Publications

Selected Publications

Journal Article

Funding

Investigator On

Supervision

Potential Supervision Topics

Advisees

Graduate Advising Relationship

Background

Education And Training

Identity

Orcid Id

Web Of Science Researcher Id

Scopus Id

Visualisations

Research Areas

Geographic Focus