Mitchell, Todd

Top Publications

Year	Title
2008	Ozone induced dissociation: elucidation of double bond position within mass-selected lipid ions Published in Analytical Chemistry
2010	Advances in mass spectrometry for lipidomics Published in Annual Review of Analytical Chemistry
2013	Surface analysis of lipids by mass spectrometry: more than just imaging Published in Progress in Lipid Research
2014	A female-gametocyte-specific ABC transporter plays a role in lipid metabolism in the malaria parasite Published in Nature Communications
2014	Structural characterization of glycerophospholipids by combinations of ozone- and collision-induced dissociation mass spectrometry: the next step towards "top-down" lipidomics Published in The Analyst

Research Areas

Available as Research Supervisor

Selected Publications

Journal Article

Year	Title
2019	Reaction of ionised steryl esters with ozone in the gas phase Published In Chemistry and Physics of Lipids Volume 221 Pages 198 - 206 ISSN 0009-3084 Altmetric
2018	A High-Throughput Method for the Analysis of Erythrocyte Fatty Acids and the Omega-3 Index Published In Lipids Volume 53 Pages 1005 - 1015 ISSN 0024-4201 Altmetric
2018	Differential-Mobility Spectrometry of 1-Deoxysphingosine Isomers: New Insights into the Gas Phase Structures of Ionized Lipids Published In Analytical Chemistry Volume 90 Pages 5343 - 5351 ISSN 0003-2700 Altmetric
2018	Discrimination of isobaric and isomeric lipids in complex mixtures by combining ultra-high pressure liquid chromatography with collision and ozone-induced dissociation Published In International Journal of Mass Spectrometry Volume 431 Pages 27 - 36 ISSN 1387-3806 Altmetric
2018	Disrupted sphingolipid metabolism following acute clozapine and olanzapine administration Published In British Journal of Biomedical Science Volume 25 Pages 40-1 - 40-11 ISSN 0967-4845 Altmetric
2018	Distribution of Glycerophospholipids in the Adult Human Lens Published In Biomolecules Volume 8 Pages 156-1 - 156-6 Altmetric
2018	Increasing Acyl CoA thioesterase activity alters phospholipid profle without effect on insulin action in skeletal muscle of rats Published In Scientific Reports Volume 8 Pages 13967-1 - 13967-12 ISSN 2045-2322 Altmetric
2018	Mass spectrometry-directed structure elucidation and total synthesis of ultra-long chain (O-acyl)-ω-hydroxy fatty acids Published In Journal of Lipid Research Volume 59 Pages 1510 - 1518 ISSN 0022-2275 Altmetric
2018	Online Ozonolysis Combined with Ion Mobility-Mass Spectrometry Provides a New Platform for Lipid Isomer Analyses Published In Analytical Chemistry Volume 90 Pages 1292 - 1300 ISSN 0003-2700 Altmetric
2017	Advances and unresolved challenges in the structural characterization of isomeric lipids Published In Analytical Biochemistry Volume 524 Pages 45 - 55 ISSN 0003-2697 Altmetric
2017	Association of muscle lipidomic profile with high-fat diet-induced insulin resistance across five mouse strains Published In Scientific Reports Volume 7 Pages 13914-1 - 13914-9 ISSN 2045-2322 Altmetric
2017	High-Pressure Ozone-Induced Dissociation for Lipid Structure Elucidation on Fast Chromatographic Timescales Published In Analytical Chemistry Volume 89 Pages 4223 - 4229 ISSN 0003-2700 Altmetric
2017	Radical Generation from the Gas-Phase Activation of Ionized Lipid Ozonides Published In Journal of the American Society for Mass Spectrometry Volume 28 Pages 1345 - 1358 ISSN 1044-0305 Altmetric
2017	The cationic small molecule GW4869 is cytotoxic to high phosphatidylserine-expressing myeloma cells Published In British Journal of Haematology Volume 177 Pages 423 - 440 ISSN 0007-1048 Altmetric
2017	The phospholipid composition of the human entorhinal cortex remains relatively stable over 80 years of adult aging Published In GeroScience Volume 39 Pages 73 - 82 Altmetric
2016	A lipidomic analysis of placenta in preeclampsia: evidence for lipid storage Published In PLoS One Volume 11 Pages 0163972-1 - 0163972-13 ISSN 1932-6203 Altmetric
2016	Annexin A6 regulates interleukin-2-mediated T-cell proliferation Published In Immunology and Cell Biology Volume 94 Pages 543 - 553 ISSN 0818-9641 Altmetric
2016	Changes in lipid composition during sexual development of the malaria parasite Plasmodium falciparum Published In Malaria Journal Volume 15 Pages 73-1 - 73-13 ISSN 1475-2875 Altmetric
2016	Determination of ester position in isomeric (O-acyl)-hydroxy fatty acids by ion trap mass spectrometry Volume 30 Pages 2351 - 2359 ISSN 0951-4198 Altmetric
2016	Influence of Meibomian gland expression methods on human lipid analysis results Published In The Ocular Surface Volume 14 Pages 49 - 55 ISSN 1542-0124 Altmetric
2016	Intersubject and interday variability in human tear and meibum lipidomes: a pilot study Published In The Ocular Surface Volume 14 Pages 43 - 48 ISSN 1542-0124 Altmetric
2016	Prolonged intake of dietary lipids alters membrane structure and T cell responses in LDLr^−/− mice Published In Journal of Immunology Volume 196 Pages 3993 - 4002 ISSN 0022-1767 Altmetric
2016	Regulation of glucose homeostasis and insulin action by ceramide acyl-chain length: A beneficial role for very long-chain sphingolipid species Published In BBA: Molecular and Cell Biology of Lipids Volume 1861 Pages 1828 - 1839 ISSN 1388-1981 Altmetric
2016	Sequential collision- and ozone-induced dissociation enables assignment of relative acyl chain position in triacylglycerols Published In Analytical Chemistry Volume 88 Pages 2685 - 2692 ISSN 0003-2700 Altmetric
2015	A rapid ambient ionization-mass spectrometry approach to monitoring the relative abundance of isomeric glycerophospholipids Published In Scientific Reports Volume 5 Pages 9243-1 - 9243-9 ISSN 2045-2322 Altmetric
2015	Combining liquid chromatography with ozone-induced dissociation for the separation and identification of phosphatidylcholine double bond isomers Published In Analytical and Bioanalytical Chemistry Volume 407 Pages 5053 - 5064 ISSN 1618-2642 Altmetric
2015	Decreases in phospholipids containing adrenic and arachidonic acids occur in the human hippocampus over the adult lifespan Published In Lipids Volume 50 Pages 861 - 872 ISSN 0024-4201 Altmetric
2015	Disparate metabolic response to fructose feeding between different mouse strains Published In Scientific Reports Volume 5 Pages 18474-1 - 18474-13 ISSN 2045-2322 Altmetric
2015	Dissociation of proton-bound complexes reveals geometry and arrangement of double bonds in unsaturated lipids Published In International Journal of Mass Spectrometry Volume 390 Pages 170 - 177 ISSN 1387-3806 Altmetric
2015	Human prefrontal cortex phospholipids containing docosahexaenoic acid increase during normal adult aging, whereas those containing arachidonic acid decrease Published In Neurobiology of Aging Volume 36 Pages 1659 - 1669 ISSN 0197-4580 Altmetric
2015	No turnover in lens lipids for the entire human lifespan Published In eLife Volume 4 Pages e06003-1 - e06003-7 ISSN 2050-084X Altmetric
2015	Of mice, pigs and humans: an analysis of mitochondrial phospholipids from mammals with very different maximal lifespans Published In Experimental Gerontology Volume 70 Pages 135 - 143 ISSN 0531-5565 Altmetric
2015	Separation and identification of phosphatidylcholine regioisomers by combining liquid chromatography with a fusion of collision-and ozone-induced dissociation Published In European Journal of Mass Spectrometry Volume 21 Pages 191 - 200 ISSN 1469-0667 Altmetric
2015	Serum-induced keratinization processes in an immortalized human meibomian gland epithelial cell line Published In PLoS One Volume 10 Pages e0128096-1 - e0128096-18 ISSN 1932-6203 Altmetric
2014	A female-gametocyte-specific ABC transporter plays a role in lipid metabolism in the malaria parasite Published In Nature Communications Volume 5 Pages 1 - 13 ISSN 2041-1723 Altmetric
2014	A high-dose Shiitake mushroom increases hepatic accumulation of triacylglycerol in rats fed a high-fat diet: underlying mechanism Published In Nutrients Volume 6 Pages 650 - 662 Altmetric
2014	Characterisation of sphingolipids in the human lens by thin layer chromatography-desorption electrospray ionisation mass spectrometry Published In BBA: Molecular and Cell Biology of Lipids Volume 1841 Pages 1285 - 1291 ISSN 1388-1981 Altmetric
2014	Characterization of acyl chain position in unsaturated phosphatidylcholines using differential mobility-mass spectrometry Published In Journal of Lipid Research Volume 55 Pages 1668 - 1677 ISSN 0022-2275 Altmetric
2014	Clinical and biochemical tear lipid parameters in contact lens wearers Published In Optometry and Vision Science Volume 91 Pages 1384 - 1390 ISSN 1040-5488 Altmetric
2014	Comparison of tear lipid profile among basal, reflex, and flush tear samples Published In Optometry and Vision Science Volume 91 Pages 1391 - 1395 ISSN 1040-5488 Altmetric
2014	Structural characterization of glycerophospholipids by combinations of ozone- and collision-induced dissociation mass spectrometry: the next step towards "top-down" lipidomics Published In The Analyst Volume 139 Pages 204 - 214 ISSN 0003-2654 Altmetric
2013	A comparison of patient matched meibum and tear lipidomes Published In Investigative Ophthalmology and Visual Science Volume 54 Pages 7417 - 7423 ISSN 0146-0404 Altmetric
2013	An Improved High-Throughput Lipid Extraction Method for the Analysis of Human Brain Lipids Published In Lipids Volume 48 Pages 307 - 318 ISSN 0024-4201 Altmetric
2013	Automated surface sampling of lipids from worn contact lenses coupled with tandem mass spectrometry Published In The Analyst Volume 138 Pages 1316 - 1320 ISSN 0003-2654 Altmetric
2013	Ceramide accumulation in L6 skeletal muscle cells due to increased activity of ceramide synthase isoforms has opposing effects on insulin action to those caused by palmitate treatment Published In Diabetologia Volume 56 Pages 2697 - 2701 ISSN 0012-186X Altmetric
2013	Contrasting metabolic effects of medium- versus long-chain fatty acids in skeletal muscle Published In Journal of Lipid Research Volume 54 Pages 3322 - 3333 ISSN 0022-2275 Altmetric
2013	High-dose mushroom increases hepatic accumulation of triacylglycerol in rats fed with high-fat diet Published In Annals of Nutrition and Metabolism: European journal of nutrition, metabolic diseases and dietetics Volume 63 Pages 1616 - 1616 ISSN 0250-6807
2013	Mouse strain-dependent variation in obesity and glucose homeostasis in response to high-fat feeding Published In Diabetologia Volume 56 Pages 1129 - 1139 ISSN 0012-186X Altmetric
2013	Ozone-induced dissociation of conjugated lipids reveals significant reaction rate enhancements and characteristic odd-electron product ions Published In Journal of the American Society for Mass Spectrometry Volume 24 Pages 286 - 296 ISSN 1044-0305 Altmetric
2013	Rapid differentiation of isomeric lipids by photodissociation mass spectrometry of fatty acid derivatives Volume 27 Pages 805 - 815 ISSN 0951-4198 Altmetric
2013	Rapid quantification of free cholesterol in tears using direct insertion/electron ionization-Mass spectrometry Published In Investigative Ophthalmology and Visual Science Volume 54 Pages 8027 - 8035 ISSN 0146-0404 Altmetric
2013	Surface analysis of lipids by mass spectrometry: more than just imaging Published In Progress in Lipid Research Volume 52 Pages 329 - 353 ISSN 0163-7827 Altmetric
2012	Clinical dyslipidaemia is associated with changes in the lipid composition and inflammatory properties of apolipoprotein-B-containing lipoproteins from women with type 2 diabetes Published In Diabetologia Volume 55 Pages 1156 - 1166 ISSN 0012-186X Altmetric
2012	Differentiation of complex lipid isomers by radical-directed dissociation mass spectrometry Published In Analytical Chemistry Volume 84 Pages 7525 - 7532 ISSN 0003-2700 Altmetric
2012	Direct detection of additives and degradation products from polymers by liquid extraction surface analysis employing chip-based nanospray mass spectrometry Volume 26 Pages 412 - 418 ISSN 0951-4198 Altmetric
2012	Direct lipid profiling of single cells from inkjet printed microarrays Published In Analytical Chemistry Volume 84 Pages 9679 - 9683 ISSN 0003-2700 Altmetric
2012	Instability of the cellular lipidome with age Published In Age Volume 34 Pages 935 - 947 ISSN 0161-9152 Altmetric
2012	Phospholipid peroxidation: lack of effect of fatty acid pairing Published In Lipids Volume 47 Pages 451 - 460 ISSN 0024-4201 Altmetric
2012	Time to face the fats: What can mass spectrometry reveal about the structure of lipids and their interactions with proteins? Published In Journal of the American Society for Mass Spectrometry Volume 23 Pages 1441 - 1449 ISSN 1044-0305 Altmetric
2012	Using ambient ozone for assignment of double bond position in unsaturated lipids Published In The Analyst Volume 137 Pages 1100 - 1110 ISSN 0003-2654 Altmetric
2011	Analysis of unsaturated lipids by ozone-induced dissociation Published In BBA: Molecular and Cell Biology of Lipids Volume 1811 Pages 807 - 817 ISSN 1388-1981 Altmetric
2011	Fatty acid uptake and incorporation into phospholipids in the rat lens. Published In Investigative Ophthalmology and Visual Science Volume 52 Pages 804 - 809 ISSN 0146-0404 Altmetric
2011	Identification of phospholipids in human meibum by nano-electrospray ionisation tandem mass spectrometry Published In Experimental Eye Research Volume 92 Pages 238 - 240 ISSN 0014-4835 Altmetric
2011	Lipid pathway alterations in Parkinson's Disease primary visual cortex Published In PLoS One Volume 6 Pages 1 - 17 ISSN 1932-6203 Altmetric
2011	The ω-3 and ω-6 fats in meals: a proposal for a simple new label Published In Nutrition Volume 27 Pages 719 - 726 ISSN 0899-9007 Altmetric
2011	Unsuccessful ageing: dramatic changes to the human lens lipidome with age Published In Clinical and Experimental Ophthalmology Volume 39 Pages 79 - 79 ISSN 1442-6404 Altmetric
2010	Advances in mass spectrometry for lipidomics Published In Annual Review of Analytical Chemistry Volume 3 Pages 433 - 465 ISSN 1936-1327 Altmetric
2010	Anti-inflammatory effects of apolipoprotein A-I in the rabbit Published In Atherosclerosis Volume 212 Pages 392 - 397 ISSN 0021-9150 Altmetric
2010	Detection and quantification of tear phospholipids and cholesterol in contact lens deposits: the effect of contact lens material and lens care solution Published In Investigative Ophthalmology and Visual Science Volume 51 Pages 2843 - 2851 ISSN 0146-0404 Altmetric
2010	Imaging of human lens lipids by desorption electrospray ionization mass spectrometry Published In Journal of the American Society for Mass Spectrometry Volume 21 Pages 2095 - 2104 ISSN 1044-0305 Altmetric
2010	Lipid analysis of phagosomal membranes Published In Journal of the American Society for Mass Spectrometry Volume 21 Pages S44 - S44 ISSN 1044-0305
2010	Ozone-induced dissociation on a modified tandem linear ion-trap: observations of different reactivity for isomeric lipids Published In Journal of the American Society for Mass Spectrometry Volume 21 Pages 1989 - 1999 ISSN 1044-0305 Altmetric
2010	Saturated- and n-6 polyunsaturated-fat diets each induce ceramide accumulation in mouse skeletal muscle: reversal and improvement of glucose tolerance by lipid metabolism inhibitors Published In Endocrinology Volume 151 Pages 4187 - 4196 ISSN 0013-7227 Altmetric
2010	Sphingolipid distribution changes with age in the human lens Published In Journal of Lipid Research Volume 51 Pages 2753 - 2760 ISSN 0022-2275 Altmetric
2010	The effect of exercise on the skeletal muscle phospholipidome of rats fed a high-fat diet Published In International Journal of Molecular Sciences Volume 11 Pages 3954 - 3964 ISSN 1661-6596 Altmetric
2010	α- and β-crystallins modulate the head group order of human lens membranes during aging Published In Investigative Ophthalmology and Visual Science Volume 51 Pages 5162 - 5167 ISSN 0146-0404 Altmetric
2009	Caveolin-1-dependent and -independent membrane domains Published In Journal of Lipid Research Volume 50 Pages 1609 - 1620 ISSN 0022-2275 Altmetric
2009	Identification of abundant alkyl ether glycerophospholipids in the human lens by tandem mass spectrometry techniques Published In Analytical Chemistry Volume 81 Pages 1920 - 1930 ISSN 0003-2700 Altmetric
2009	Identification of double bond position in lipids: from GC to OzID Published In Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences Volume 877 Pages 2722 - 2735 ISSN 1570-0232 Altmetric
2009	Online ozonolysis methods for the determination of double bond position in unsaturated lipids Published In Methods in Molecular Biology Volume 579 Pages 413 - 441 ISSN 1064-3745
2008	Human lens lipids differ markedly from those of commonly used experimental animals Published In BBA: Molecular and Cell Biology of Lipids Volume 1781 Pages 288 - 298 ISSN 1388-1981 Altmetric
2008	Ozone induced dissociation: elucidation of double bond position within mass-selected lipid ions Published In Analytical Chemistry Volume 80 Pages 303 - 311 ISSN 0003-2700 Altmetric
2008	Phospholipid composition of the rat lens is independent of diet Published In Experimental Eye Research Volume 87 Pages 502 - 514 ISSN 0014-4835 Altmetric
2008	Systematic differences in membrane acyl composition associated with varying body mass in mammals occur in all phospholipid classes: an analysis of kidney and brain Published In The Journal of Experimental Biology Volume 211 Pages 3195 - 3204 ISSN 0022-0949 Altmetric
2007	Differences in membrane acyl phospholipid composition between an endothermic mammal and an ectothermic reptile are not limited to any phospholipid class Published In The Journal of Experimental Biology Volume 210 Pages 3440 - 3450 ISSN 0022-0949 Altmetric
2007	Dilinoleoyl-Phosphatidic Acid Mediates Reduced IRS-1 Tyrosine Phosphorylation In Rat Skeletal Muscle Cells and Mouse Muscle Published In Diabetologia Volume 50 Pages 1732 - 1742 ISSN 0012-186X Altmetric
2007	Elucidation of double bond position in unsaturated lipids by ozone electrospray ionization mass spectrometry Published In Analytical Chemistry Volume 79 Pages 5013 - 5022 ISSN 0003-2700 Altmetric
2007	Interactions between apolipoprotein A-1 and plasma membrane lipid domains, leading to phospholipid and cholesterol export Published In Chemistry and Physics of Lipids Volume 149 Page p. S17 ISSN 0009-3084
2007	Membrane phospholipid composition may contribute to exceptional longevity of the naked mole-rat (Heterocephalus glaber): A comparative study using shotgun lipidomics Published In Experimental Gerontology Volume 42 Pages 1053 - 1062 ISSN 0531-5565 Altmetric

Chapter

Year	Title
2012	Structural lipidomics Published In Lipidomics: Technologies and Applications Publisher Wiley-VCH Verlag GmbH Pages 99 - 128 Altmetric
2009	Tracking the glycerophospholipid distribution of docosahexaenoic acid by shotgun lipidomics Published In Lipidomics: methods and protocols Publisher Humana Press Pages 19 - 31 Altmetric

Conference Paper

Year	Title
2012	Membrane lipids in human lenses and age Published In ISER 2012: XX Biennial Meeting of the International society for Eye Research - Abstracts Page p. O461
2010	Imaging of abundant human lens lipids by desorption electrospray ionization mass spectrometry Published In 58th ASMS Conference on Mass Spectrometry Pages 1 - 1
2010	Lenses, lipids and life: understanding age-related alterations in fibre cell membranes Published In XIX Biennial Meeting of the International Society for Eye Research
2010	Lipidomic assessment of Parkinson's disease brain Published In Australian Neuroscience Society Annual Meeting, Sydney 2010 Page p. 186
2010	Ozone induced dissociation for lipodomics workflows Published In 58th ASMS Conference on Mass Spectrometry Pages 1 - 1
2010	Phospholipids in tears, contact lenses and meibum? Published In 6th International Conference on the Tear Film and Ocular Surface: Basic Science and Clinical Relevance Page p. 105
2010	Quantification of triacylglycerols regioisomers present in lipid extracts by CID and CID/OzID techniques Published In 58th ASMS Conference on Mass Spectrometry Pages 1 - 1
2010	The lipid composition of the human lens nucleus alters substantially with age Published In ISER 2010: XIX Biennial Meeting of the International Society for Eye Research, Montreal, Canada, 2010
2009	A down under approach to top-down lipidomics: towards the full structural characterisation of lipids by mass spectrometry Published In Frontier Lipidology: Lipidomics in Health and Disease Pages 26 - 26
2009	Alterations in human lens membrane phospholipids with age Published In 22nd Australian and New Zealand Society for Mass Spectrometry Page p. 113
2009	Apathetic amphipathic? Searching for phospholipid biomarkers of dry eye Published In Solving Dry Eye: An International Exchange Pages 9 - 9
2009	Are lipidomics analyses greatly underestimating lipid diversity? Published In 21st ASMS Sanibel Conference on Mass Spectrometry
2009	Big fat tears: a mass spectrometric investigation of phospholipids in tears and contact lens deposits Published In Solving dry eye: an international exchange Pages 18 - 18
2009	Electrospray ionisation mass spectrometry reveals age-related alterations in human lens phospholipid composition Published In 57th ASMS Conference on Mass Spectrometry and Allied Topics Pages 1 - 1
2009	Human lens lipids: their structure, turnover and distribution Published In Frontier Lipidology: Lipidomics in Health and Disease Page p. 35
2009	Lipid MS: observations from the lens Published In ACT Mass Spectrometry Symposium 2009 Page p. 15
2009	Lipid analysis of phagosomal membranes Published In 22nd Australian and New Zealand Society for Mass Spectrometry Pages 94 - 94
2009	Lipids in tears and on contact lenses: a shotgun lipidomic analysis Published In 22nd Australian and New Zealand Society for Mass Spectrometry Pages 93 - 93
2009	Lisofylline and myriocin improve insulin action in mice fed diets rich in either polyunsaturated or saturated fats Published In Keystone Symposia on Type 2 Diabetes and Insulin Resistance Pages 1 - 1
2009	New insights into the human lens through multi-faceted lipid mass spectrometry Published In 57th ASMS Conference on Mass Spectrometry and Allied Topics Pages 1 - 1
2009	Ozone induced dissociation in structure elucidation Published In 57th ASMS Conference on Mass Spectrometry and Allied Topics Pages 1 - 1
2009	Structural characterisation of triacylglycerols (TAGs) prsent in very low density lipoprotein by ozone-induced dissociation (OzID) Published In 22nd Australian and New Zealand Society for Mass Spectrometry Pages 89 - 89
2009	The search for a barrier in the middle aged human lens: visualising lipid distribution by MALDI-imaging Published In 22nd Australian and New Zealand Society for Mass Spectrometry Pages 138 - 138
2009	Unusual reaction product from the gas-phase ozonolysis of an unsaturated phosphatidylethanolamine sodium adduct: possible insights into the ozonolysis mechanism Published In ANZSMS 22: 22nd Australian and New Zealand Society for Mass Spectrometry Pages 80 - 80
2009	Visualizing the sphingolipid distribution of the human lens Published In 18th International Mass Spectrometry Conference Pages 1 - 2
2007	Ceramides and diet induced insulin resistance in rats: new insights from ESI-MS Published In Australian and New Zealand Society for Mass Spectrometry 21st Conference Page p. 76
2007	Heads or tails? What is the important link between membrane phospholipids, body mass and metabolism? Published In Australian and New Zealand Society for Mass Spectrometry 21st Conference Page p. 65

Investigator On

Year	Title
2019 - 2021	Pluses and minuses of lipid mass spectrometry Awarded by: Australian Research Council (ARC) Funding Scheme: Discovery Projects
2017 - 2019	Understanding sphingolipid mediators of insulin resistance Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2018	Developing next generation mass spectrometry imaging with isomer resolution Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Projects
2018	NSW molecular analysis platform: FTICR mass spectrometer and CHN&S analyser Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2012 - 2016	Lipidomics of vision Awarded by: Australian Research Council (ARC) Funding Scheme: Future Fellowships
2011 - 2016	Development of Ozone-Induced Dissociation for Lipidomics Workflows Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Projects
2012 - 2015	New laser and mass spectrometry-based tools for comprehensive structural elucidation of lipids and their biomolecular interactions Awarded by: Australian Research Council (ARC) Funding Scheme: Discovery Projects
2014	Characterisation of tear film lipids Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Projects
2013	Advanced High Resolution Mass Spectrometer for Collaborative Proteomic and Lipidomics Research Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2012	Multiplexed capabilities for surface analysis and imaging by mass spectrometry Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2011	Ancient proteins and disease Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2011	Microbial infestation of pre-painted steel building materials: chemical and microbial characterization, model development and control strategies Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Projects
2011	Targeting ceramide metabolism to improve lipi-induced insulin resistance Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2010	Fat for life: using accelerator mass spectrometry to determine the lifespan of human lens lipids Awarded by: Australian Institute of Nuclear Science and Engineering (AINSE) Funding Scheme: Research Award
2010	Regional facility for molecular characterisation and mapping Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2009	Identifying tear lipids, their deposition onto contact lenses and their role in the development of dry eye Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Projects
2009	New methods to complete the lipidomics puzzle: revealing the structural diversity of lipids by mass spectrometry Awarded by: Australian Research Council (ARC) Funding Scheme: Discovery Projects
2009	Unique state-of-the-art lipidomics infrastructure Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2008	Dilinoleoyl phosphatidic acid as a novel mediator of insulin resistance in muscle Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
	Developing next generation technologies for unmasking the lipidome Awarded by: Australian Research Council (ARC) Funding Scheme: Discovery Projects

Available as Research Supervisor

Advisees

Graduate Advising Relationship

Degree	Research Title	Advisee
Doctor of Philosophy	Characterisation of Alterations in Lipid Pathways in Huntington's Disease. A High-throughput Lipidomic Assessment of Disease Pathways .
Doctor of Philosophy	The Effect of Liposome Treatment on Calcium Signalling and Nitric Oxide in Cholinergic Neurons During Alzheimer's Disease	Balez, Rachelle
Doctor of Philosophy	Laser Techniques to Detect and Identify Protonation Isomers	Marlton, Samuel
Doctor of Philosophy	Timing Exercise to Attenuate Peak Postprandial Hyperglycemia in Type 2 Diabetes	Chang, Courtney
Doctor of Philosophy	Distribution of lipids in the human lens and the affect of ageing	Seng, Jo Ann

Top Publications

Year	Title
2008	Ozone induced dissociation: elucidation of double bond position within mass-selected lipid ions Published in Analytical Chemistry
2010	Advances in mass spectrometry for lipidomics Published in Annual Review of Analytical Chemistry
2013	Surface analysis of lipids by mass spectrometry: more than just imaging Published in Progress in Lipid Research
2014	A female-gametocyte-specific ABC transporter plays a role in lipid metabolism in the malaria parasite Published in Nature Communications
2014	Structural characterization of glycerophospholipids by combinations of ozone- and collision-induced dissociation mass spectrometry: the next step towards "top-down" lipidomics Published in The Analyst

Research Areas

Selected Publications

Journal Article

Year	Title
2019	Reaction of ionised steryl esters with ozone in the gas phase Published In Chemistry and Physics of Lipids Volume 221 Pages 198 - 206 ISSN 0009-3084 Altmetric
2018	A High-Throughput Method for the Analysis of Erythrocyte Fatty Acids and the Omega-3 Index Published In Lipids Volume 53 Pages 1005 - 1015 ISSN 0024-4201 Altmetric
2018	Differential-Mobility Spectrometry of 1-Deoxysphingosine Isomers: New Insights into the Gas Phase Structures of Ionized Lipids Published In Analytical Chemistry Volume 90 Pages 5343 - 5351 ISSN 0003-2700 Altmetric
2018	Discrimination of isobaric and isomeric lipids in complex mixtures by combining ultra-high pressure liquid chromatography with collision and ozone-induced dissociation Published In International Journal of Mass Spectrometry Volume 431 Pages 27 - 36 ISSN 1387-3806 Altmetric
2018	Disrupted sphingolipid metabolism following acute clozapine and olanzapine administration Published In British Journal of Biomedical Science Volume 25 Pages 40-1 - 40-11 ISSN 0967-4845 Altmetric
2018	Distribution of Glycerophospholipids in the Adult Human Lens Published In Biomolecules Volume 8 Pages 156-1 - 156-6 Altmetric
2018	Increasing Acyl CoA thioesterase activity alters phospholipid profle without effect on insulin action in skeletal muscle of rats Published In Scientific Reports Volume 8 Pages 13967-1 - 13967-12 ISSN 2045-2322 Altmetric
2018	Mass spectrometry-directed structure elucidation and total synthesis of ultra-long chain (O-acyl)-ω-hydroxy fatty acids Published In Journal of Lipid Research Volume 59 Pages 1510 - 1518 ISSN 0022-2275 Altmetric
2018	Online Ozonolysis Combined with Ion Mobility-Mass Spectrometry Provides a New Platform for Lipid Isomer Analyses Published In Analytical Chemistry Volume 90 Pages 1292 - 1300 ISSN 0003-2700 Altmetric
2017	Advances and unresolved challenges in the structural characterization of isomeric lipids Published In Analytical Biochemistry Volume 524 Pages 45 - 55 ISSN 0003-2697 Altmetric
2017	Association of muscle lipidomic profile with high-fat diet-induced insulin resistance across five mouse strains Published In Scientific Reports Volume 7 Pages 13914-1 - 13914-9 ISSN 2045-2322 Altmetric
2017	High-Pressure Ozone-Induced Dissociation for Lipid Structure Elucidation on Fast Chromatographic Timescales Published In Analytical Chemistry Volume 89 Pages 4223 - 4229 ISSN 0003-2700 Altmetric
2017	Radical Generation from the Gas-Phase Activation of Ionized Lipid Ozonides Published In Journal of the American Society for Mass Spectrometry Volume 28 Pages 1345 - 1358 ISSN 1044-0305 Altmetric
2017	The cationic small molecule GW4869 is cytotoxic to high phosphatidylserine-expressing myeloma cells Published In British Journal of Haematology Volume 177 Pages 423 - 440 ISSN 0007-1048 Altmetric
2017	The phospholipid composition of the human entorhinal cortex remains relatively stable over 80 years of adult aging Published In GeroScience Volume 39 Pages 73 - 82 Altmetric
2016	A lipidomic analysis of placenta in preeclampsia: evidence for lipid storage Published In PLoS One Volume 11 Pages 0163972-1 - 0163972-13 ISSN 1932-6203 Altmetric
2016	Annexin A6 regulates interleukin-2-mediated T-cell proliferation Published In Immunology and Cell Biology Volume 94 Pages 543 - 553 ISSN 0818-9641 Altmetric
2016	Changes in lipid composition during sexual development of the malaria parasite Plasmodium falciparum Published In Malaria Journal Volume 15 Pages 73-1 - 73-13 ISSN 1475-2875 Altmetric
2016	Determination of ester position in isomeric (O-acyl)-hydroxy fatty acids by ion trap mass spectrometry Volume 30 Pages 2351 - 2359 ISSN 0951-4198 Altmetric
2016	Influence of Meibomian gland expression methods on human lipid analysis results Published In The Ocular Surface Volume 14 Pages 49 - 55 ISSN 1542-0124 Altmetric
2016	Intersubject and interday variability in human tear and meibum lipidomes: a pilot study Published In The Ocular Surface Volume 14 Pages 43 - 48 ISSN 1542-0124 Altmetric
2016	Prolonged intake of dietary lipids alters membrane structure and T cell responses in LDLr^−/− mice Published In Journal of Immunology Volume 196 Pages 3993 - 4002 ISSN 0022-1767 Altmetric
2016	Regulation of glucose homeostasis and insulin action by ceramide acyl-chain length: A beneficial role for very long-chain sphingolipid species Published In BBA: Molecular and Cell Biology of Lipids Volume 1861 Pages 1828 - 1839 ISSN 1388-1981 Altmetric
2016	Sequential collision- and ozone-induced dissociation enables assignment of relative acyl chain position in triacylglycerols Published In Analytical Chemistry Volume 88 Pages 2685 - 2692 ISSN 0003-2700 Altmetric
2015	A rapid ambient ionization-mass spectrometry approach to monitoring the relative abundance of isomeric glycerophospholipids Published In Scientific Reports Volume 5 Pages 9243-1 - 9243-9 ISSN 2045-2322 Altmetric
2015	Combining liquid chromatography with ozone-induced dissociation for the separation and identification of phosphatidylcholine double bond isomers Published In Analytical and Bioanalytical Chemistry Volume 407 Pages 5053 - 5064 ISSN 1618-2642 Altmetric
2015	Decreases in phospholipids containing adrenic and arachidonic acids occur in the human hippocampus over the adult lifespan Published In Lipids Volume 50 Pages 861 - 872 ISSN 0024-4201 Altmetric
2015	Disparate metabolic response to fructose feeding between different mouse strains Published In Scientific Reports Volume 5 Pages 18474-1 - 18474-13 ISSN 2045-2322 Altmetric
2015	Dissociation of proton-bound complexes reveals geometry and arrangement of double bonds in unsaturated lipids Published In International Journal of Mass Spectrometry Volume 390 Pages 170 - 177 ISSN 1387-3806 Altmetric
2015	Human prefrontal cortex phospholipids containing docosahexaenoic acid increase during normal adult aging, whereas those containing arachidonic acid decrease Published In Neurobiology of Aging Volume 36 Pages 1659 - 1669 ISSN 0197-4580 Altmetric
2015	No turnover in lens lipids for the entire human lifespan Published In eLife Volume 4 Pages e06003-1 - e06003-7 ISSN 2050-084X Altmetric
2015	Of mice, pigs and humans: an analysis of mitochondrial phospholipids from mammals with very different maximal lifespans Published In Experimental Gerontology Volume 70 Pages 135 - 143 ISSN 0531-5565 Altmetric
2015	Separation and identification of phosphatidylcholine regioisomers by combining liquid chromatography with a fusion of collision-and ozone-induced dissociation Published In European Journal of Mass Spectrometry Volume 21 Pages 191 - 200 ISSN 1469-0667 Altmetric
2015	Serum-induced keratinization processes in an immortalized human meibomian gland epithelial cell line Published In PLoS One Volume 10 Pages e0128096-1 - e0128096-18 ISSN 1932-6203 Altmetric
2014	A female-gametocyte-specific ABC transporter plays a role in lipid metabolism in the malaria parasite Published In Nature Communications Volume 5 Pages 1 - 13 ISSN 2041-1723 Altmetric
2014	A high-dose Shiitake mushroom increases hepatic accumulation of triacylglycerol in rats fed a high-fat diet: underlying mechanism Published In Nutrients Volume 6 Pages 650 - 662 Altmetric
2014	Characterisation of sphingolipids in the human lens by thin layer chromatography-desorption electrospray ionisation mass spectrometry Published In BBA: Molecular and Cell Biology of Lipids Volume 1841 Pages 1285 - 1291 ISSN 1388-1981 Altmetric
2014	Characterization of acyl chain position in unsaturated phosphatidylcholines using differential mobility-mass spectrometry Published In Journal of Lipid Research Volume 55 Pages 1668 - 1677 ISSN 0022-2275 Altmetric
2014	Clinical and biochemical tear lipid parameters in contact lens wearers Published In Optometry and Vision Science Volume 91 Pages 1384 - 1390 ISSN 1040-5488 Altmetric
2014	Comparison of tear lipid profile among basal, reflex, and flush tear samples Published In Optometry and Vision Science Volume 91 Pages 1391 - 1395 ISSN 1040-5488 Altmetric
2014	Structural characterization of glycerophospholipids by combinations of ozone- and collision-induced dissociation mass spectrometry: the next step towards "top-down" lipidomics Published In The Analyst Volume 139 Pages 204 - 214 ISSN 0003-2654 Altmetric
2013	A comparison of patient matched meibum and tear lipidomes Published In Investigative Ophthalmology and Visual Science Volume 54 Pages 7417 - 7423 ISSN 0146-0404 Altmetric
2013	An Improved High-Throughput Lipid Extraction Method for the Analysis of Human Brain Lipids Published In Lipids Volume 48 Pages 307 - 318 ISSN 0024-4201 Altmetric
2013	Automated surface sampling of lipids from worn contact lenses coupled with tandem mass spectrometry Published In The Analyst Volume 138 Pages 1316 - 1320 ISSN 0003-2654 Altmetric
2013	Ceramide accumulation in L6 skeletal muscle cells due to increased activity of ceramide synthase isoforms has opposing effects on insulin action to those caused by palmitate treatment Published In Diabetologia Volume 56 Pages 2697 - 2701 ISSN 0012-186X Altmetric
2013	Contrasting metabolic effects of medium- versus long-chain fatty acids in skeletal muscle Published In Journal of Lipid Research Volume 54 Pages 3322 - 3333 ISSN 0022-2275 Altmetric
2013	High-dose mushroom increases hepatic accumulation of triacylglycerol in rats fed with high-fat diet Published In Annals of Nutrition and Metabolism: European journal of nutrition, metabolic diseases and dietetics Volume 63 Pages 1616 - 1616 ISSN 0250-6807
2013	Mouse strain-dependent variation in obesity and glucose homeostasis in response to high-fat feeding Published In Diabetologia Volume 56 Pages 1129 - 1139 ISSN 0012-186X Altmetric
2013	Ozone-induced dissociation of conjugated lipids reveals significant reaction rate enhancements and characteristic odd-electron product ions Published In Journal of the American Society for Mass Spectrometry Volume 24 Pages 286 - 296 ISSN 1044-0305 Altmetric
2013	Rapid differentiation of isomeric lipids by photodissociation mass spectrometry of fatty acid derivatives Volume 27 Pages 805 - 815 ISSN 0951-4198 Altmetric
2013	Rapid quantification of free cholesterol in tears using direct insertion/electron ionization-Mass spectrometry Published In Investigative Ophthalmology and Visual Science Volume 54 Pages 8027 - 8035 ISSN 0146-0404 Altmetric
2013	Surface analysis of lipids by mass spectrometry: more than just imaging Published In Progress in Lipid Research Volume 52 Pages 329 - 353 ISSN 0163-7827 Altmetric
2012	Clinical dyslipidaemia is associated with changes in the lipid composition and inflammatory properties of apolipoprotein-B-containing lipoproteins from women with type 2 diabetes Published In Diabetologia Volume 55 Pages 1156 - 1166 ISSN 0012-186X Altmetric
2012	Differentiation of complex lipid isomers by radical-directed dissociation mass spectrometry Published In Analytical Chemistry Volume 84 Pages 7525 - 7532 ISSN 0003-2700 Altmetric
2012	Direct detection of additives and degradation products from polymers by liquid extraction surface analysis employing chip-based nanospray mass spectrometry Volume 26 Pages 412 - 418 ISSN 0951-4198 Altmetric
2012	Direct lipid profiling of single cells from inkjet printed microarrays Published In Analytical Chemistry Volume 84 Pages 9679 - 9683 ISSN 0003-2700 Altmetric
2012	Instability of the cellular lipidome with age Published In Age Volume 34 Pages 935 - 947 ISSN 0161-9152 Altmetric
2012	Phospholipid peroxidation: lack of effect of fatty acid pairing Published In Lipids Volume 47 Pages 451 - 460 ISSN 0024-4201 Altmetric
2012	Time to face the fats: What can mass spectrometry reveal about the structure of lipids and their interactions with proteins? Published In Journal of the American Society for Mass Spectrometry Volume 23 Pages 1441 - 1449 ISSN 1044-0305 Altmetric
2012	Using ambient ozone for assignment of double bond position in unsaturated lipids Published In The Analyst Volume 137 Pages 1100 - 1110 ISSN 0003-2654 Altmetric
2011	Analysis of unsaturated lipids by ozone-induced dissociation Published In BBA: Molecular and Cell Biology of Lipids Volume 1811 Pages 807 - 817 ISSN 1388-1981 Altmetric
2011	Fatty acid uptake and incorporation into phospholipids in the rat lens. Published In Investigative Ophthalmology and Visual Science Volume 52 Pages 804 - 809 ISSN 0146-0404 Altmetric
2011	Identification of phospholipids in human meibum by nano-electrospray ionisation tandem mass spectrometry Published In Experimental Eye Research Volume 92 Pages 238 - 240 ISSN 0014-4835 Altmetric
2011	Lipid pathway alterations in Parkinson's Disease primary visual cortex Published In PLoS One Volume 6 Pages 1 - 17 ISSN 1932-6203 Altmetric
2011	The ω-3 and ω-6 fats in meals: a proposal for a simple new label Published In Nutrition Volume 27 Pages 719 - 726 ISSN 0899-9007 Altmetric
2011	Unsuccessful ageing: dramatic changes to the human lens lipidome with age Published In Clinical and Experimental Ophthalmology Volume 39 Pages 79 - 79 ISSN 1442-6404 Altmetric
2010	Advances in mass spectrometry for lipidomics Published In Annual Review of Analytical Chemistry Volume 3 Pages 433 - 465 ISSN 1936-1327 Altmetric
2010	Anti-inflammatory effects of apolipoprotein A-I in the rabbit Published In Atherosclerosis Volume 212 Pages 392 - 397 ISSN 0021-9150 Altmetric
2010	Detection and quantification of tear phospholipids and cholesterol in contact lens deposits: the effect of contact lens material and lens care solution Published In Investigative Ophthalmology and Visual Science Volume 51 Pages 2843 - 2851 ISSN 0146-0404 Altmetric
2010	Imaging of human lens lipids by desorption electrospray ionization mass spectrometry Published In Journal of the American Society for Mass Spectrometry Volume 21 Pages 2095 - 2104 ISSN 1044-0305 Altmetric
2010	Lipid analysis of phagosomal membranes Published In Journal of the American Society for Mass Spectrometry Volume 21 Pages S44 - S44 ISSN 1044-0305
2010	Ozone-induced dissociation on a modified tandem linear ion-trap: observations of different reactivity for isomeric lipids Published In Journal of the American Society for Mass Spectrometry Volume 21 Pages 1989 - 1999 ISSN 1044-0305 Altmetric
2010	Saturated- and n-6 polyunsaturated-fat diets each induce ceramide accumulation in mouse skeletal muscle: reversal and improvement of glucose tolerance by lipid metabolism inhibitors Published In Endocrinology Volume 151 Pages 4187 - 4196 ISSN 0013-7227 Altmetric
2010	Sphingolipid distribution changes with age in the human lens Published In Journal of Lipid Research Volume 51 Pages 2753 - 2760 ISSN 0022-2275 Altmetric
2010	The effect of exercise on the skeletal muscle phospholipidome of rats fed a high-fat diet Published In International Journal of Molecular Sciences Volume 11 Pages 3954 - 3964 ISSN 1661-6596 Altmetric
2010	α- and β-crystallins modulate the head group order of human lens membranes during aging Published In Investigative Ophthalmology and Visual Science Volume 51 Pages 5162 - 5167 ISSN 0146-0404 Altmetric
2009	Caveolin-1-dependent and -independent membrane domains Published In Journal of Lipid Research Volume 50 Pages 1609 - 1620 ISSN 0022-2275 Altmetric
2009	Identification of abundant alkyl ether glycerophospholipids in the human lens by tandem mass spectrometry techniques Published In Analytical Chemistry Volume 81 Pages 1920 - 1930 ISSN 0003-2700 Altmetric
2009	Identification of double bond position in lipids: from GC to OzID Published In Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences Volume 877 Pages 2722 - 2735 ISSN 1570-0232 Altmetric
2009	Online ozonolysis methods for the determination of double bond position in unsaturated lipids Published In Methods in Molecular Biology Volume 579 Pages 413 - 441 ISSN 1064-3745
2008	Human lens lipids differ markedly from those of commonly used experimental animals Published In BBA: Molecular and Cell Biology of Lipids Volume 1781 Pages 288 - 298 ISSN 1388-1981 Altmetric
2008	Ozone induced dissociation: elucidation of double bond position within mass-selected lipid ions Published In Analytical Chemistry Volume 80 Pages 303 - 311 ISSN 0003-2700 Altmetric
2008	Phospholipid composition of the rat lens is independent of diet Published In Experimental Eye Research Volume 87 Pages 502 - 514 ISSN 0014-4835 Altmetric
2008	Systematic differences in membrane acyl composition associated with varying body mass in mammals occur in all phospholipid classes: an analysis of kidney and brain Published In The Journal of Experimental Biology Volume 211 Pages 3195 - 3204 ISSN 0022-0949 Altmetric
2007	Differences in membrane acyl phospholipid composition between an endothermic mammal and an ectothermic reptile are not limited to any phospholipid class Published In The Journal of Experimental Biology Volume 210 Pages 3440 - 3450 ISSN 0022-0949 Altmetric
2007	Dilinoleoyl-Phosphatidic Acid Mediates Reduced IRS-1 Tyrosine Phosphorylation In Rat Skeletal Muscle Cells and Mouse Muscle Published In Diabetologia Volume 50 Pages 1732 - 1742 ISSN 0012-186X Altmetric
2007	Elucidation of double bond position in unsaturated lipids by ozone electrospray ionization mass spectrometry Published In Analytical Chemistry Volume 79 Pages 5013 - 5022 ISSN 0003-2700 Altmetric
2007	Interactions between apolipoprotein A-1 and plasma membrane lipid domains, leading to phospholipid and cholesterol export Published In Chemistry and Physics of Lipids Volume 149 Page p. S17 ISSN 0009-3084
2007	Membrane phospholipid composition may contribute to exceptional longevity of the naked mole-rat (Heterocephalus glaber): A comparative study using shotgun lipidomics Published In Experimental Gerontology Volume 42 Pages 1053 - 1062 ISSN 0531-5565 Altmetric

Chapter

Year	Title
2012	Structural lipidomics Published In Lipidomics: Technologies and Applications Publisher Wiley-VCH Verlag GmbH Pages 99 - 128 Altmetric
2009	Tracking the glycerophospholipid distribution of docosahexaenoic acid by shotgun lipidomics Published In Lipidomics: methods and protocols Publisher Humana Press Pages 19 - 31 Altmetric

Conference Paper

Year	Title
2012	Membrane lipids in human lenses and age Published In ISER 2012: XX Biennial Meeting of the International society for Eye Research - Abstracts Page p. O461
2010	Imaging of abundant human lens lipids by desorption electrospray ionization mass spectrometry Published In 58th ASMS Conference on Mass Spectrometry Pages 1 - 1
2010	Lenses, lipids and life: understanding age-related alterations in fibre cell membranes Published In XIX Biennial Meeting of the International Society for Eye Research
2010	Lipidomic assessment of Parkinson's disease brain Published In Australian Neuroscience Society Annual Meeting, Sydney 2010 Page p. 186
2010	Ozone induced dissociation for lipodomics workflows Published In 58th ASMS Conference on Mass Spectrometry Pages 1 - 1
2010	Phospholipids in tears, contact lenses and meibum? Published In 6th International Conference on the Tear Film and Ocular Surface: Basic Science and Clinical Relevance Page p. 105
2010	Quantification of triacylglycerols regioisomers present in lipid extracts by CID and CID/OzID techniques Published In 58th ASMS Conference on Mass Spectrometry Pages 1 - 1
2010	The lipid composition of the human lens nucleus alters substantially with age Published In ISER 2010: XIX Biennial Meeting of the International Society for Eye Research, Montreal, Canada, 2010
2009	A down under approach to top-down lipidomics: towards the full structural characterisation of lipids by mass spectrometry Published In Frontier Lipidology: Lipidomics in Health and Disease Pages 26 - 26
2009	Alterations in human lens membrane phospholipids with age Published In 22nd Australian and New Zealand Society for Mass Spectrometry Page p. 113
2009	Apathetic amphipathic? Searching for phospholipid biomarkers of dry eye Published In Solving Dry Eye: An International Exchange Pages 9 - 9
2009	Are lipidomics analyses greatly underestimating lipid diversity? Published In 21st ASMS Sanibel Conference on Mass Spectrometry
2009	Big fat tears: a mass spectrometric investigation of phospholipids in tears and contact lens deposits Published In Solving dry eye: an international exchange Pages 18 - 18
2009	Electrospray ionisation mass spectrometry reveals age-related alterations in human lens phospholipid composition Published In 57th ASMS Conference on Mass Spectrometry and Allied Topics Pages 1 - 1
2009	Human lens lipids: their structure, turnover and distribution Published In Frontier Lipidology: Lipidomics in Health and Disease Page p. 35
2009	Lipid MS: observations from the lens Published In ACT Mass Spectrometry Symposium 2009 Page p. 15
2009	Lipid analysis of phagosomal membranes Published In 22nd Australian and New Zealand Society for Mass Spectrometry Pages 94 - 94
2009	Lipids in tears and on contact lenses: a shotgun lipidomic analysis Published In 22nd Australian and New Zealand Society for Mass Spectrometry Pages 93 - 93
2009	Lisofylline and myriocin improve insulin action in mice fed diets rich in either polyunsaturated or saturated fats Published In Keystone Symposia on Type 2 Diabetes and Insulin Resistance Pages 1 - 1
2009	New insights into the human lens through multi-faceted lipid mass spectrometry Published In 57th ASMS Conference on Mass Spectrometry and Allied Topics Pages 1 - 1
2009	Ozone induced dissociation in structure elucidation Published In 57th ASMS Conference on Mass Spectrometry and Allied Topics Pages 1 - 1
2009	Structural characterisation of triacylglycerols (TAGs) prsent in very low density lipoprotein by ozone-induced dissociation (OzID) Published In 22nd Australian and New Zealand Society for Mass Spectrometry Pages 89 - 89
2009	The search for a barrier in the middle aged human lens: visualising lipid distribution by MALDI-imaging Published In 22nd Australian and New Zealand Society for Mass Spectrometry Pages 138 - 138
2009	Unusual reaction product from the gas-phase ozonolysis of an unsaturated phosphatidylethanolamine sodium adduct: possible insights into the ozonolysis mechanism Published In ANZSMS 22: 22nd Australian and New Zealand Society for Mass Spectrometry Pages 80 - 80
2009	Visualizing the sphingolipid distribution of the human lens Published In 18th International Mass Spectrometry Conference Pages 1 - 2
2007	Ceramides and diet induced insulin resistance in rats: new insights from ESI-MS Published In Australian and New Zealand Society for Mass Spectrometry 21st Conference Page p. 76
2007	Heads or tails? What is the important link between membrane phospholipids, body mass and metabolism? Published In Australian and New Zealand Society for Mass Spectrometry 21st Conference Page p. 65

Investigator On

Year	Title
2019 - 2021	Pluses and minuses of lipid mass spectrometry Awarded by: Australian Research Council (ARC) Funding Scheme: Discovery Projects
2017 - 2019	Understanding sphingolipid mediators of insulin resistance Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2018	Developing next generation mass spectrometry imaging with isomer resolution Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Projects
2018	NSW molecular analysis platform: FTICR mass spectrometer and CHN&S analyser Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2012 - 2016	Lipidomics of vision Awarded by: Australian Research Council (ARC) Funding Scheme: Future Fellowships
2011 - 2016	Development of Ozone-Induced Dissociation for Lipidomics Workflows Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Projects
2012 - 2015	New laser and mass spectrometry-based tools for comprehensive structural elucidation of lipids and their biomolecular interactions Awarded by: Australian Research Council (ARC) Funding Scheme: Discovery Projects
2014	Characterisation of tear film lipids Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Projects
2013	Advanced High Resolution Mass Spectrometer for Collaborative Proteomic and Lipidomics Research Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2012	Multiplexed capabilities for surface analysis and imaging by mass spectrometry Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2011	Ancient proteins and disease Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2011	Microbial infestation of pre-painted steel building materials: chemical and microbial characterization, model development and control strategies Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Projects
2011	Targeting ceramide metabolism to improve lipi-induced insulin resistance Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
2010	Fat for life: using accelerator mass spectrometry to determine the lifespan of human lens lipids Awarded by: Australian Institute of Nuclear Science and Engineering (AINSE) Funding Scheme: Research Award
2010	Regional facility for molecular characterisation and mapping Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2009	Identifying tear lipids, their deposition onto contact lenses and their role in the development of dry eye Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Projects
2009	New methods to complete the lipidomics puzzle: revealing the structural diversity of lipids by mass spectrometry Awarded by: Australian Research Council (ARC) Funding Scheme: Discovery Projects
2009	Unique state-of-the-art lipidomics infrastructure Awarded by: Australian Research Council (ARC) Funding Scheme: Linkage Infrastructure Equipment & Facilities (LIEF)
2008	Dilinoleoyl phosphatidic acid as a novel mediator of insulin resistance in muscle Awarded by: National Health and Medical Research Council (NHMRC) Funding Scheme: Project Grant
	Developing next generation technologies for unmasking the lipidome Awarded by: Australian Research Council (ARC) Funding Scheme: Discovery Projects

Advisees

Graduate Advising Relationship

Degree	Research Title	Advisee
Doctor of Philosophy	Characterisation of Alterations in Lipid Pathways in Huntington's Disease. A High-throughput Lipidomic Assessment of Disease Pathways .
Doctor of Philosophy	The Effect of Liposome Treatment on Calcium Signalling and Nitric Oxide in Cholinergic Neurons During Alzheimer's Disease	Balez, Rachelle
Doctor of Philosophy	Laser Techniques to Detect and Identify Protonation Isomers	Marlton, Samuel
Doctor of Philosophy	Timing Exercise to Attenuate Peak Postprandial Hyperglycemia in Type 2 Diabetes	Chang, Courtney
Doctor of Philosophy	Distribution of lipids in the human lens and the affect of ageing	Seng, Jo Ann

Mitchell, Todd

Associate Professor

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Available as Research Supervisor

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