Finol Urdaneta, Rocio

Overview

Year	Title
2019	Conotoxin κM-RIIIJ, a tool targeting asymmetric heteromeric Kv1 channels Published in Proceedings of the National Academy of Sciences of USA
2014	Sodium channel selectivity and conduction: Prokaryotes have devised their own molecular strategy Published in Journal of General Physiology

Year

Title

2019

Conotoxin κM-RIIIJ, a tool targeting asymmetric heteromeric Kv1 channels
Published in Proceedings of the National Academy of Sciences of USA

2014

Sodium channel selectivity and conduction: Prokaryotes have devised their own molecular strategy
Published in Journal of General Physiology

Publications

Selected Publications

Journal Article

Year	Title
2022	Analgesic ¿-conotoxins modulate native and recombinant GIRK1/2 channels via activation of GABAB receptors and reduce neuroexcitability Published In British Journal of Pharmacology
2021	Analgesic ¿-conotoxins modulate native and recombinant GIRK1/2 channels via activation of GABAB receptors and reduce neuroexcitability Published In British Journal of Pharmacology
2021	In vivo survival and differentiation of Friedreich ataxia iPSC-derived sensory neurons transplanted in the adult dorsal root ganglia Published In Stem Cells Translational Medicine
2021	Non-Peptidic Small Molecule Components from Cone Snail Venoms Published In Frontiers in Pharmacology
2021	Small-molecule mimicry hunting strategy in the imperial cone snail, Conus imperialis Published In Science Advances
2021	Spider Venom Peptide Pn3a Inhibition of Primary Afferent High Voltage-Activated Calcium Channels Published In Frontiers in Pharmacology
2020	A method for high-content functional imaging of intracellular calcium responses in gelatin-immobilized non-adherent cells Published In Experimental Cell Research
2020	An integrative approach to the facile functional classification of dorsal root ganglion neuronal subclasses Published In Proceedings of the National Academy of Sciences of the United States of America
2020	Marine toxins targeting KV1 channels: Pharmacological tools and therapeutic scaffolds Published In Marine Drugs
2020	Modulation of Native and Recombinant GIRK1/2 Channels by Analgesic alpha-conotoxins Published In BIOPHYSICAL JOURNAL
2020	Molecular and Functional Characterization of Neurogenin-2 Induced Human Sensory Neurons Published In Frontiers in Cellular Neuroscience
2020	N-alkylisatin-based microtubule destabilizers bind to the colchicine site on tubulin and retain efficacy in drug resistant acute lymphoblastic leukemia cell lines with less in vitro neurotoxicity Published In CANCER CELL INTERNATIONAL
2020	Pharmacological and genetic characterisation of the canine P2X4 receptor Published In British Journal of Pharmacology
2020	Structural basis of the potency and selectivity of Urotoxin, a potent Kv1 blocker from scorpion venom Published In Biochemical Pharmacology
2019	Author Correction: Bases of Bacterial Sodium Channel Selectivity Among Organic Cations (Scientific Reports, (2019), 9, 1, (15260), 10.1038/s41598-019-51605-y) Published In Scientific Reports
2019	Bases of Bacterial Sodium Channel Selectivity Among Organic Cations Published In Scientific Reports
2019	Batrachotoxin acts as a stent to hold open homotetrameric prokaryotic voltage-gated sodium channels Published In Journal of General Physiology
2019	Conotoxin κM-RIIIJ, a tool targeting asymmetric heteromeric Kv1 channels Published In Proceedings of the National Academy of Sciences of USA
2019	Extremely potent block of bacterial voltage-gated sodium channels by µ-conotoxin PIIIA Published In Marine Drugs
2018	NMR structure of µ-conotoxin GIIIC: Leucine 18 induces local repacking of the N-terminus resulting in reduced Nav channel potency Published In Molecules
2017	Analgesic conopeptides targeting G protein-coupled receptors reduce excitability of sensory neurons Published In Neuropharmacology
2017	Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET Published In Proceedings of the National Academy of Sciences of USA
2016	Functional Modification of Bacterial Voltage-Gated Sodium Channels by Batrachotoxin Published In BIOPHYSICAL JOURNAL
2014	Sodium channel selectivity and conduction: Prokaryotes have devised their own molecular strategy Published In Journal of General Physiology
2012	Block of K v1.7 potassium currents increases glucose-stimulated insulin secretion Published In EMBO Molecular Medicine
2012	Open-state stabilization in Kv channels: Voltage-sensor relaxation and pore propping by a bound ion Published In Journal of General Physiology
2011	Discrimination Among Heteromeric Potassium Channels by Pore-Blocking Conotoxins Published In BIOPHYSICAL JOURNAL
2010	Biochemical characterization of ¿M-RIIIJ, a Kv1.2 channel blocker: Evaluation of cardioprotective effects of ¿M-conotoxins Published In Journal of Biological Chemistry
2010	Modulation of KvAP unitary conductance and gating by 1-alkanols and other surface active agents. Published In Biophysical Journal
2006	Molecular and functional differences between heart mKv1.7 channel isoforms Published In Journal of General Physiology

Conference Paper

Year	Title
2016	Bases of Sodium Channel Selectivity Among Organic Cations Published In BIOPHYSICAL JOURNAL
2016	Probing Voltage-Dependent Structural Changes of the VSD in Mammalian Nav with LRET Published In BIOPHYSICAL JOURNAL
2015	"Use Dependence" Without a Ball and Chain - Inhibition of Bacterial Sodium Channels by mu-Contoxins Published In BIOPHYSICAL JOURNAL
2014	Searching for the Interaction Sites of the Beta1 Subunit with the Voltage-Sensing Domains of Sodium Channels Using LRET Published In BIOPHYSICAL JOURNAL
2014	Tracking Voltage-Dependent Conformational Changes of the VSD in Nav with LRET Published In BIOPHYSICAL JOURNAL
2013	Polymodal, High Affinity Actions of mu-Conotoxins on a Bacterial Voltage-Gated Sodium Channel Published In BIOPHYSICAL JOURNAL
2012	Monovalent Ion Selectivity of the Homotetrameric Bacterial Na Channel, NaChBac Published In BIOPHYSICAL JOURNAL
2009	Kv1.7-Interactions with Protons and a blocking Conotoxin Published In BIOPHYSICAL JOURNAL

Supervision

Advisees

Graduate Advising Relationship

Degree	Research Title	Advisee
Doctor of Philosophy	Nicotinic acetylcholine receptor structure and function probed with venom derived peptides.

Overview

Year	Title
2019	Conotoxin κM-RIIIJ, a tool targeting asymmetric heteromeric Kv1 channels Published in Proceedings of the National Academy of Sciences of USA
2014	Sodium channel selectivity and conduction: Prokaryotes have devised their own molecular strategy Published in Journal of General Physiology

Year

Title

2019

Conotoxin κM-RIIIJ, a tool targeting asymmetric heteromeric Kv1 channels
Published in Proceedings of the National Academy of Sciences of USA

2014

Sodium channel selectivity and conduction: Prokaryotes have devised their own molecular strategy
Published in Journal of General Physiology

Publications

Year

Title

2022

Analgesic ¿-conotoxins modulate native and recombinant GIRK1/2 channels via activation of GABAB receptors and reduce neuroexcitability

Published In

British Journal of Pharmacology

2021

Analgesic ¿-conotoxins modulate native and recombinant GIRK1/2 channels via activation of GABAB receptors and reduce neuroexcitability

Published In

British Journal of Pharmacology

2021

In vivo survival and differentiation of Friedreich ataxia iPSC-derived sensory neurons transplanted in the adult dorsal root ganglia

Published In

Stem Cells Translational Medicine

2021

Non-Peptidic Small Molecule Components from Cone Snail Venoms

Published In

Frontiers in Pharmacology

2021

Small-molecule mimicry hunting strategy in the imperial cone snail, Conus imperialis

Published In

Science Advances

2021

Spider Venom Peptide Pn3a Inhibition of Primary Afferent High Voltage-Activated Calcium Channels

Published In

Frontiers in Pharmacology

2020

A method for high-content functional imaging of intracellular calcium responses in gelatin-immobilized non-adherent cells

Published In

Experimental Cell Research

2020

An integrative approach to the facile functional classification of dorsal root ganglion neuronal subclasses

Published In

Proceedings of the National Academy of Sciences of the United States of America

2020

Marine toxins targeting KV1 channels: Pharmacological tools and therapeutic scaffolds

Published In

Marine Drugs

2020

Modulation of Native and Recombinant GIRK1/2 Channels by Analgesic alpha-conotoxins

Published In

BIOPHYSICAL JOURNAL

2020

Molecular and Functional Characterization of Neurogenin-2 Induced Human Sensory Neurons

Published In

Frontiers in Cellular Neuroscience

2020

N-alkylisatin-based microtubule destabilizers bind to the colchicine site on tubulin and retain efficacy in drug resistant acute lymphoblastic leukemia cell lines with less in vitro neurotoxicity

Published In

CANCER CELL INTERNATIONAL

2020

Pharmacological and genetic characterisation of the canine P2X4 receptor

Published In

British Journal of Pharmacology

2020

Structural basis of the potency and selectivity of Urotoxin, a potent Kv1 blocker from scorpion venom

Published In

Biochemical Pharmacology

2019

Author Correction: Bases of Bacterial Sodium Channel Selectivity Among Organic Cations (Scientific Reports, (2019), 9, 1, (15260), 10.1038/s41598-019-51605-y)

Published In

Scientific Reports

2019

Bases of Bacterial Sodium Channel Selectivity Among Organic Cations

Published In

Scientific Reports

2019

Batrachotoxin acts as a stent to hold open homotetrameric prokaryotic voltage-gated sodium channels

Published In

Journal of General Physiology

2019

Conotoxin κM-RIIIJ, a tool targeting asymmetric heteromeric Kv1 channels

Published In

Proceedings of the National Academy of Sciences of USA

2019

Extremely potent block of bacterial voltage-gated sodium channels by µ-conotoxin PIIIA

Published In

Marine Drugs

2018

NMR structure of µ-conotoxin GIIIC: Leucine 18 induces local repacking of the N-terminus resulting in reduced Nav channel potency

Published In

Molecules

2017

Analgesic conopeptides targeting G protein-coupled receptors reduce excitability of sensory neurons

Published In

Neuropharmacology

2017

Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET

Published In

Proceedings of the National Academy of Sciences of USA

2016

Functional Modification of Bacterial Voltage-Gated Sodium Channels by Batrachotoxin

Published In

BIOPHYSICAL JOURNAL

2014

Sodium channel selectivity and conduction: Prokaryotes have devised their own molecular strategy

Published In

Journal of General Physiology

2012

Block of K v1.7 potassium currents increases glucose-stimulated insulin secretion

Published In

EMBO Molecular Medicine

2012

Open-state stabilization in Kv channels: Voltage-sensor relaxation and pore propping by a bound ion

Published In

Journal of General Physiology

2011

Discrimination Among Heteromeric Potassium Channels by Pore-Blocking Conotoxins

Published In

BIOPHYSICAL JOURNAL

2010

Biochemical characterization of ¿M-RIIIJ, a Kv1.2 channel blocker: Evaluation of cardioprotective effects of ¿M-conotoxins

Published In

Journal of Biological Chemistry

2010

Modulation of KvAP unitary conductance and gating by 1-alkanols and other surface active agents.

Published In

Biophysical Journal

2006

Molecular and functional differences between heart mKv1.7 channel isoforms

Published In

Journal of General Physiology

Year

Title

2016

Bases of Sodium Channel Selectivity Among Organic Cations

Published In

BIOPHYSICAL JOURNAL

2016

Probing Voltage-Dependent Structural Changes of the VSD in Mammalian Nav with LRET

Published In

BIOPHYSICAL JOURNAL

2015

"Use Dependence" Without a Ball and Chain - Inhibition of Bacterial Sodium Channels by mu-Contoxins

Published In

BIOPHYSICAL JOURNAL

2014

Searching for the Interaction Sites of the Beta1 Subunit with the Voltage-Sensing Domains of Sodium Channels Using LRET

Published In

BIOPHYSICAL JOURNAL

2014

Tracking Voltage-Dependent Conformational Changes of the VSD in Nav with LRET

Published In

BIOPHYSICAL JOURNAL

2013

Polymodal, High Affinity Actions of mu-Conotoxins on a Bacterial Voltage-Gated Sodium Channel

Published In

BIOPHYSICAL JOURNAL

2012

Monovalent Ion Selectivity of the Homotetrameric Bacterial Na Channel, NaChBac

Published In

BIOPHYSICAL JOURNAL

2009

Kv1.7-Interactions with Protons and a blocking Conotoxin

Published In

BIOPHYSICAL JOURNAL

Supervision

Advisees

Graduate Advising Relationship

Degree	Research Title	Advisee
Doctor of Philosophy	Nicotinic acetylcholine receptor structure and function probed with venom derived peptides.

Finol Urdaneta, Rocio

Senior Research Fellow

Overview

Top Publications

Publications

Selected Publications

Journal Article

Conference Paper

Supervision

Advisees

Graduate Advising Relationship

Overview

Top Publications

Publications

Selected Publications

Journal Article

Conference Paper

Supervision

Advisees

Graduate Advising Relationship

Visualisations