The north-eastern shelf successions of the Oligocene to Middle Miocene South China Sea (SCS) have attracted considerable interest because of recent hydrocarbon exploration success. However, their stratigraphic-depositional patterns and interactive controls still remain less understood. Based on integrated analyses of seismic, well-logging, core data and paleontological data, we systematically document the sequence architecture and depositional evolution of north-eastern shelf of the Pearl River Mouth Basin (PRMB) in the northern SCS. The infill of the Late Oligocene to Middle Miocene successions on the north-eastern continental shelf of the PRMB can be divided into three composite sequences (CS3-CS5) and nine sequences. Depositional-geomorphological systems represented on the shelf mainly include inner-middle shelf deltas, shoreface deposits, reefal platforms, shelf sand-ridges and fine-grained deposits. Large-scale shelf-deltaic deposits are prominent in CS3, whereas the rapid Early Miocene transgression, apparently enhanced by tectonic subsidence, caused a great retreat of Hanjiang River-related systems in CS4. The deposition of during 33.9 Ma to 17.5 Ma is constructed by a ���sandstones-carbonate-shale��� regressive-transgressive cycle in the proximal domain on the northern continental margin of the SCS. A muddy-prone deposition of CS5 is related to the enhanced tectonic subsidence with possible less sediment supply. The NE-striking geomorphic pattern of sand-ridge related systems possibly caused by the intensification of the south-westerly flowing paleocurrent likely related to the Dongsha Movement after ca. 13.8 Ma. The shoreface deposits (23.8���21 Ma) and reefal platform deposits (21���18.5 Ma) served as potential hydrocarbon reservoir and further exploration in shelf area of the SCS.