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Impact of a cancer clinical trials web site on discussions about trial participation: A cluster randomized trial

Journal Article


Abstract


  • Background: Cancer patients want access to reliable information about currently recruiting clinical trials. Patients and methods: Oncologists and their patients were randomly assigned to access a consumer-friendly cancer clinical trials web site [Australian Cancer Trials (ACT), . www.australiancancertrials.gov.au] or to usual care in a cluster randomized controlled trial. The primary outcome, measured from audio recordings of oncologist-patient consultations, was the proportion of patients with whom participation in any clinical trial was discussed. Analysis was by intention-to-treat accounting for clustering and stratification. Results: Thirty medical oncologists and 493 patients were recruited. Overall, 46% of consultations in the intervention group compared with 34% in the control group contained a discussion about clinical trials (P = 0.08). The mean consultation length in both groups was 29 min (P = 0.69). The proportion consenting to a trial was 10% in both groups (P = 0.65). Patients' knowledge about randomized trials was lower in the intervention than the control group (mean score 3.0 versus 3.3, P = 0.03) but decisional conflict scores were similar (mean score 42 versus 43, P = 0.83). Conclusions: Good communication between patients and physicians is essential. Within this context, a web site such as Australian Cancer Trials may be an important tool to encourage discussion about clinical trial participation. �� The Author 2012. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved.

Publication Date


  • 2012

Citation


  • Dear, R. F., Barratt, A. L., Askie, L. M., Butow, P. N., Mcgeechan, K., Crossing, S., . . . Tattersall, M. H. N. (2012). Impact of a cancer clinical trials web site on discussions about trial participation: A cluster randomized trial. Annals of Oncology, 23(7), 1912-1918. doi:10.1093/annonc/mdr585

Scopus Eid


  • 2-s2.0-84864325487

Start Page


  • 1912

End Page


  • 1918

Volume


  • 23

Issue


  • 7

Place Of Publication


Abstract


  • Background: Cancer patients want access to reliable information about currently recruiting clinical trials. Patients and methods: Oncologists and their patients were randomly assigned to access a consumer-friendly cancer clinical trials web site [Australian Cancer Trials (ACT), . www.australiancancertrials.gov.au] or to usual care in a cluster randomized controlled trial. The primary outcome, measured from audio recordings of oncologist-patient consultations, was the proportion of patients with whom participation in any clinical trial was discussed. Analysis was by intention-to-treat accounting for clustering and stratification. Results: Thirty medical oncologists and 493 patients were recruited. Overall, 46% of consultations in the intervention group compared with 34% in the control group contained a discussion about clinical trials (P = 0.08). The mean consultation length in both groups was 29 min (P = 0.69). The proportion consenting to a trial was 10% in both groups (P = 0.65). Patients' knowledge about randomized trials was lower in the intervention than the control group (mean score 3.0 versus 3.3, P = 0.03) but decisional conflict scores were similar (mean score 42 versus 43, P = 0.83). Conclusions: Good communication between patients and physicians is essential. Within this context, a web site such as Australian Cancer Trials may be an important tool to encourage discussion about clinical trial participation. �� The Author 2012. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved.

Publication Date


  • 2012

Citation


  • Dear, R. F., Barratt, A. L., Askie, L. M., Butow, P. N., Mcgeechan, K., Crossing, S., . . . Tattersall, M. H. N. (2012). Impact of a cancer clinical trials web site on discussions about trial participation: A cluster randomized trial. Annals of Oncology, 23(7), 1912-1918. doi:10.1093/annonc/mdr585

Scopus Eid


  • 2-s2.0-84864325487

Start Page


  • 1912

End Page


  • 1918

Volume


  • 23

Issue


  • 7

Place Of Publication