Skip to main content
placeholder image

Oxygen for relief of dyspnoea in people with chronic obstructive pulmonary disease who would not qualify for home oxygen: A systematic review and meta-analysis

Journal Article


Abstract


  • We searched MEDLINE, EMBASE and the Cochrane Controlled Trials Register to determine whether oxygen relieves dyspnoea in mildly or non-hypoxemic COPD and included 18 randomised controlled trials (431 participants) in the meta-analysis using Cochrane methodology. Oxygen therapy reduced dyspnoea when compared with medical air; standardised mean difference -0.37 (95% CI -0.50 to -0.24; I2=14%). In a priori subgroup and sensitivity analyses, dyspnoea was reduced by continuous oxygen during exertion but not short-burst oxygen therapy. Continuous exertional oxygen can relieve dyspnoea in mildly or non-hypoxemic COPD, but evidence from larger clinical trials is needed.

Publication Date


  • 2015

Publisher


Published In


Citation


  • Uronis, H. E., Ekstr��m, M. P., Currow, D. C., McCrory, D. C., Samsa, G. P., & Abernethy, A. P. (2015). Oxygen for relief of dyspnoea in people with chronic obstructive pulmonary disease who would not qualify for home oxygen: A systematic review and meta-analysis. Thorax, 70(5), 492-494. doi:10.1136/thoraxjnl-2014-205720

Scopus Eid


  • 2-s2.0-84929459132

Start Page


  • 492

End Page


  • 494

Volume


  • 70

Issue


  • 5

Place Of Publication


Abstract


  • We searched MEDLINE, EMBASE and the Cochrane Controlled Trials Register to determine whether oxygen relieves dyspnoea in mildly or non-hypoxemic COPD and included 18 randomised controlled trials (431 participants) in the meta-analysis using Cochrane methodology. Oxygen therapy reduced dyspnoea when compared with medical air; standardised mean difference -0.37 (95% CI -0.50 to -0.24; I2=14%). In a priori subgroup and sensitivity analyses, dyspnoea was reduced by continuous oxygen during exertion but not short-burst oxygen therapy. Continuous exertional oxygen can relieve dyspnoea in mildly or non-hypoxemic COPD, but evidence from larger clinical trials is needed.

Publication Date


  • 2015

Publisher


Published In


Citation


  • Uronis, H. E., Ekstr��m, M. P., Currow, D. C., McCrory, D. C., Samsa, G. P., & Abernethy, A. P. (2015). Oxygen for relief of dyspnoea in people with chronic obstructive pulmonary disease who would not qualify for home oxygen: A systematic review and meta-analysis. Thorax, 70(5), 492-494. doi:10.1136/thoraxjnl-2014-205720

Scopus Eid


  • 2-s2.0-84929459132

Start Page


  • 492

End Page


  • 494

Volume


  • 70

Issue


  • 5

Place Of Publication