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Highly Efficient Adsorption of Bilirubin by Ti3C2Tx MXene

Journal Article


Abstract


  • We discovered that the 2D Ti3C2Tx MXene sheet displays an ultra-high removal capability for bilirubin (BR). In particular, MXene shows 47.6 times higher removal efficiency over traditional activated carbon absorbents. The effect of MXene on the removal rate of BR in BR solution containing different concentrations of bovine serum albumin (BSA) was studied. The adsorption capacity of BSA for BR at high concentration of 5 g L−1 was about 85% of the best adsorption capacity. The MXene before and after adsorption was characterized by SEM, FT-IR and XPS. Furthermore, MXene beads were prepared, and the hemoperfusion simulation experiment was carried out. The results show that the adsorption capacity of MXene for bilirubin can reach 1192.9 mg g−1. This study suggests that MXene may be promising in the treatment of hyperbilirubinemia.

UOW Authors


  •   Wang, Guoxiu (external author)

Publication Date


  • 2021

Citation


  • Sun, X., Yang, J., Su, D., Wang, C., & Wang, G. (2021). Highly Efficient Adsorption of Bilirubin by Ti3C2Tx MXene. Chemistry - An Asian Journal, 16(14), 1949-1955. doi:10.1002/asia.202100332

Scopus Eid


  • 2-s2.0-85107608012

Start Page


  • 1949

End Page


  • 1955

Volume


  • 16

Issue


  • 14

Abstract


  • We discovered that the 2D Ti3C2Tx MXene sheet displays an ultra-high removal capability for bilirubin (BR). In particular, MXene shows 47.6 times higher removal efficiency over traditional activated carbon absorbents. The effect of MXene on the removal rate of BR in BR solution containing different concentrations of bovine serum albumin (BSA) was studied. The adsorption capacity of BSA for BR at high concentration of 5 g L−1 was about 85% of the best adsorption capacity. The MXene before and after adsorption was characterized by SEM, FT-IR and XPS. Furthermore, MXene beads were prepared, and the hemoperfusion simulation experiment was carried out. The results show that the adsorption capacity of MXene for bilirubin can reach 1192.9 mg g−1. This study suggests that MXene may be promising in the treatment of hyperbilirubinemia.

UOW Authors


  •   Wang, Guoxiu (external author)

Publication Date


  • 2021

Citation


  • Sun, X., Yang, J., Su, D., Wang, C., & Wang, G. (2021). Highly Efficient Adsorption of Bilirubin by Ti3C2Tx MXene. Chemistry - An Asian Journal, 16(14), 1949-1955. doi:10.1002/asia.202100332

Scopus Eid


  • 2-s2.0-85107608012

Start Page


  • 1949

End Page


  • 1955

Volume


  • 16

Issue


  • 14