Skip to main content
placeholder image

Postsynthetic Modification of Half-Sandwich Ruthenium Complexes by Mechanochemical Synthesis

Journal Article


Abstract


  • A mild and environmentally friendly method to synthesize half-sandwich ruthenium complexes through the Wittig reaction between an aldehyde-tagged half-sandwich ruthenium complex and phosphorus ylide mechanochemically is reported herein. The mechanochemical synthesis of valuable half-sandwich ruthenium complexes resulted in a fast reaction, good yield with simple workup, and the avoidance of harsh reaction conditions and organic solvents. The synthesized half-sandwich ruthenium complexes exhibited high catalytic activity for transfer hydrogenation of ketones using 2-propanol as the hydrogen source and solvent. Density functional theory was carried out to propose a mechanism for the transfer hydrogenation process. The modeling suggests the importance of the labile p-cymene ligand in modulating the reactivity of the catalyst.

Publication Date


  • 2021

Citation


  • Jia, W. G., Zhi, X. T., Li, X. D., Zhou, J. P., Zhong, R., Yu, H., & Lee, R. (2021). Postsynthetic Modification of Half-Sandwich Ruthenium Complexes by Mechanochemical Synthesis. Inorganic Chemistry, 60(7), 4313-4321. doi:10.1021/acs.inorgchem.1c00059

Scopus Eid


  • 2-s2.0-85103994477

Start Page


  • 4313

End Page


  • 4321

Volume


  • 60

Issue


  • 7

Abstract


  • A mild and environmentally friendly method to synthesize half-sandwich ruthenium complexes through the Wittig reaction between an aldehyde-tagged half-sandwich ruthenium complex and phosphorus ylide mechanochemically is reported herein. The mechanochemical synthesis of valuable half-sandwich ruthenium complexes resulted in a fast reaction, good yield with simple workup, and the avoidance of harsh reaction conditions and organic solvents. The synthesized half-sandwich ruthenium complexes exhibited high catalytic activity for transfer hydrogenation of ketones using 2-propanol as the hydrogen source and solvent. Density functional theory was carried out to propose a mechanism for the transfer hydrogenation process. The modeling suggests the importance of the labile p-cymene ligand in modulating the reactivity of the catalyst.

Publication Date


  • 2021

Citation


  • Jia, W. G., Zhi, X. T., Li, X. D., Zhou, J. P., Zhong, R., Yu, H., & Lee, R. (2021). Postsynthetic Modification of Half-Sandwich Ruthenium Complexes by Mechanochemical Synthesis. Inorganic Chemistry, 60(7), 4313-4321. doi:10.1021/acs.inorgchem.1c00059

Scopus Eid


  • 2-s2.0-85103994477

Start Page


  • 4313

End Page


  • 4321

Volume


  • 60

Issue


  • 7