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Exploring new avenues for modifying course of progression of Alzheimer's disease: The rise of natural medicine

Journal Article


Abstract


  • With a constantly growing elderly population worldwide, a focus on developing efficient prevention and therapy for Alzheimer's disease (AD) seems timely and topical. Emphasis on natural medicine is increasingly popular in the search for drug candidates that are capable of preventing and treating AD related pathology, particularly where suppression of amyloid accumulation, neurofibrillary tangle formation, neuroinflammation and oxidative stress are equally significant. A number of phytochemical compounds have been shown to collectively reduce these AD hallmarks with the progression of natural drug candidates into human clinical trials. This review focuses on current research surrounding the therapies emerging within natural medicines and their related therapeutic potential for AD treatment.

Publication Date


  • 2021

Citation


  • Lye, S., Aust, C. E., Griffiths, L. R., & Fernandez, F. (2021). Exploring new avenues for modifying course of progression of Alzheimer's disease: The rise of natural medicine. Journal of the Neurological Sciences, 422. doi:10.1016/j.jns.2021.117332

Scopus Eid


  • 2-s2.0-85101028727

Web Of Science Accession Number


Volume


  • 422

Abstract


  • With a constantly growing elderly population worldwide, a focus on developing efficient prevention and therapy for Alzheimer's disease (AD) seems timely and topical. Emphasis on natural medicine is increasingly popular in the search for drug candidates that are capable of preventing and treating AD related pathology, particularly where suppression of amyloid accumulation, neurofibrillary tangle formation, neuroinflammation and oxidative stress are equally significant. A number of phytochemical compounds have been shown to collectively reduce these AD hallmarks with the progression of natural drug candidates into human clinical trials. This review focuses on current research surrounding the therapies emerging within natural medicines and their related therapeutic potential for AD treatment.

Publication Date


  • 2021

Citation


  • Lye, S., Aust, C. E., Griffiths, L. R., & Fernandez, F. (2021). Exploring new avenues for modifying course of progression of Alzheimer's disease: The rise of natural medicine. Journal of the Neurological Sciences, 422. doi:10.1016/j.jns.2021.117332

Scopus Eid


  • 2-s2.0-85101028727

Web Of Science Accession Number


Volume


  • 422