We present the integration of a novel Dielectrophoresis (DEP)-assisted filter on a compact disc (CD)-like centrifugal platform. Carbon-electrode Dielectrophoresis (CarbonDEP) refers to the use of carbon surfaces as electrodes to induce DEP. The system utilizes 3D carbon electrodes as a DEP active filter to trap particles of interest in a solution. Compared to traditional DEP devices that employ planar metal electrodes, the 3D carbon electrode structure allows for superior filter throughput. By placing 3D carbon electrodes on a rotating disk, we reduce the footprint of the typical DEP system by eliminating bulky precision pumps and fluidic interconnects. To demonstrate the system setup as an efficient filtering mechanism we separated latex particles from a mix of latex and yeast cells at flow rates up to 40 ul/min. ©2009 IEEE.