Cu9Ni6Sn alloys were prepared by conventional casting (CC) and twin-roll casting (TRC). The CC-processed specimens possessed dendritic structures, and Sn was distributed mainly in the inter-dendritic region and formed dendritic segregation. The TRC-processed specimens were composed of equiaxed grains and a heterogeneous structure. The distribution of Sn showed gradient characteristics, with more Sn in the surface layer and less Sn in the center. The TRC-processed specimens had more inhomogeneous mechanical properties than the CC-processed specimens.