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Honey, I Shrunk the DNA: DNA lenght as a probe for nucleic-acid enzyme activity

Journal Article


Abstract


  • The replication, recombination, and repair of DNA are processes essential for the maintenance of genomic information and require the activity of numerous enzymes that catalyze the polymerization or digestion of DNA. This review will discuss how differences in elastic properties between single- and double-stranded DNA can be used as a probe to study the dynamics of these enzymes at the single-molecule level. © 2006 Wiley Periodicals, Inc.

Publication Date


  • 2007

Citation


  • Van Oijen, A. M. (2007). Honey, I Shrunk the DNA: DNA lenght as a probe for nucleic-acid enzyme activity. Biopolymers, 85(2), 144-153. doi:10.1002/bip.20624

Scopus Eid


  • 2-s2.0-33847156024

Start Page


  • 144

End Page


  • 153

Volume


  • 85

Issue


  • 2

Abstract


  • The replication, recombination, and repair of DNA are processes essential for the maintenance of genomic information and require the activity of numerous enzymes that catalyze the polymerization or digestion of DNA. This review will discuss how differences in elastic properties between single- and double-stranded DNA can be used as a probe to study the dynamics of these enzymes at the single-molecule level. © 2006 Wiley Periodicals, Inc.

Publication Date


  • 2007

Citation


  • Van Oijen, A. M. (2007). Honey, I Shrunk the DNA: DNA lenght as a probe for nucleic-acid enzyme activity. Biopolymers, 85(2), 144-153. doi:10.1002/bip.20624

Scopus Eid


  • 2-s2.0-33847156024

Start Page


  • 144

End Page


  • 153

Volume


  • 85

Issue


  • 2