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Repressed by a NuRD

Journal Article


Abstract

  • Embryonic stem (ES) cells deficient in Mbd3, a component of the nucleosome remodelling complex (NuRD), exhibit LIF-independent self-renewal and a restricted potential to differentiate. As such, it is likely that NuRD is required for ES cell pluripotency, and represents a potential link between maintaining the undifferentiated state and the capacity to differentiate. © 2006, Nature Publishing Group Ltd. All rights reserved.

Publication Date

  • 2006

Citation

  • Crook, J. M., Ray Dunn, N., & Colman, A. (2006). Repressed by a NuRD. Nature Cell Biology, 8(3), 212-214. doi:10.1038/ncb0306-212

Scopus Eid

  • 2-s2.0-33646054905

Start Page

  • 212

End Page

  • 214

Volume

  • 8

Issue

  • 3

Abstract

  • Embryonic stem (ES) cells deficient in Mbd3, a component of the nucleosome remodelling complex (NuRD), exhibit LIF-independent self-renewal and a restricted potential to differentiate. As such, it is likely that NuRD is required for ES cell pluripotency, and represents a potential link between maintaining the undifferentiated state and the capacity to differentiate. © 2006, Nature Publishing Group Ltd. All rights reserved.

Publication Date

  • 2006

Citation

  • Crook, J. M., Ray Dunn, N., & Colman, A. (2006). Repressed by a NuRD. Nature Cell Biology, 8(3), 212-214. doi:10.1038/ncb0306-212

Scopus Eid

  • 2-s2.0-33646054905

Start Page

  • 212

End Page

  • 214

Volume

  • 8

Issue

  • 3