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Asymmetric Conjugate Addition of Organometallic Reagents to Chiral Vinyl Sulfoximines

Journal Article


Abstract


  • The chiral vinyl sulfoximines 1 and 2 (R‘ = C6H5, CH3,n-Bu, C6H5CH2CH2) have been prepared; they undergo conjugate addition reactions with organometallic reagents with high asymmetric induction. These conjugate addition adducts have been converted to chiral 3-alkylalkanoic acids in high enantiomeric excess (>90%). © 1986, American Chemical Society. All rights reserved.

Publication Date


  • 1986

Citation


  • Pyne, S. G. (1986). Asymmetric Conjugate Addition of Organometallic Reagents to Chiral Vinyl Sulfoximines. Journal of Organic Chemistry, 51(1), 81-87. doi:10.1021/jo00351a017

Scopus Eid


  • 2-s2.0-33845374042

Web Of Science Accession Number


Start Page


  • 81

End Page


  • 87

Volume


  • 51

Issue


  • 1

Abstract


  • The chiral vinyl sulfoximines 1 and 2 (R‘ = C6H5, CH3,n-Bu, C6H5CH2CH2) have been prepared; they undergo conjugate addition reactions with organometallic reagents with high asymmetric induction. These conjugate addition adducts have been converted to chiral 3-alkylalkanoic acids in high enantiomeric excess (>90%). © 1986, American Chemical Society. All rights reserved.

Publication Date


  • 1986

Citation


  • Pyne, S. G. (1986). Asymmetric Conjugate Addition of Organometallic Reagents to Chiral Vinyl Sulfoximines. Journal of Organic Chemistry, 51(1), 81-87. doi:10.1021/jo00351a017

Scopus Eid


  • 2-s2.0-33845374042

Web Of Science Accession Number


Start Page


  • 81

End Page


  • 87

Volume


  • 51

Issue


  • 1