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Asymmetric intramolecular conjugate addition of amines to chiral vinyl sulphoxides. Total synthesis of (R)-(+)-Carnegine

Journal Article


Abstract


  • The (E)- and vinyl sulphoxides (3) and (4) upon treatment with base, undergo cyclization to give chiral isoquinolines one of which was converted into (R) - (+)-carnegine. © Royal Society of Chemistry.

Publication Date


  • 1986

Citation


  • Pyne, S. G., & Chapman, S. L. (1986). Asymmetric intramolecular conjugate addition of amines to chiral vinyl sulphoxides. Total synthesis of (R)-(+)-Carnegine. Journal of the Chemical Society - Series Chemical Communications, 1688-1689. doi:10.1039/C39860001688

Scopus Eid


  • 2-s2.0-37049067217

Web Of Science Accession Number


Start Page


  • 1688

End Page


  • 1689

Abstract


  • The (E)- and vinyl sulphoxides (3) and (4) upon treatment with base, undergo cyclization to give chiral isoquinolines one of which was converted into (R) - (+)-carnegine. © Royal Society of Chemistry.

Publication Date


  • 1986

Citation


  • Pyne, S. G., & Chapman, S. L. (1986). Asymmetric intramolecular conjugate addition of amines to chiral vinyl sulphoxides. Total synthesis of (R)-(+)-Carnegine. Journal of the Chemical Society - Series Chemical Communications, 1688-1689. doi:10.1039/C39860001688

Scopus Eid


  • 2-s2.0-37049067217

Web Of Science Accession Number


Start Page


  • 1688

End Page


  • 1689