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Diastereoselective Michael Reactions of Azomethine Ylides to Chiral 4-Methyleneoxazolidin-5-ones: Synthesis of the Four Stereoisomers of 4-Benzamidopyroglutamate

Journal Article


Abstract


  • The diastereoselective Michael addition reactions of the azomethine ylides derived from the α-(alkylideneamino) esters 2, 3 and 17 with the chiral oxazolidinones 1 and 8 allow for a practical synthesis of all four stereoisomers of 4-benzamidopyroglutamate.

Publication Date


  • 1997

Citation


  • Javidan, A., Schafer, K., & Pyne, S. G. (1997). Diastereoselective Michael Reactions of Azomethine Ylides to Chiral 4-Methyleneoxazolidin-5-ones: Synthesis of the Four Stereoisomers of 4-Benzamidopyroglutamate. Synlett, 1997(1), 100-102.

Scopus Eid


  • 2-s2.0-0002782416

Web Of Science Accession Number


Start Page


  • 100

End Page


  • 102

Volume


  • 1997

Issue


  • 1

Abstract


  • The diastereoselective Michael addition reactions of the azomethine ylides derived from the α-(alkylideneamino) esters 2, 3 and 17 with the chiral oxazolidinones 1 and 8 allow for a practical synthesis of all four stereoisomers of 4-benzamidopyroglutamate.

Publication Date


  • 1997

Citation


  • Javidan, A., Schafer, K., & Pyne, S. G. (1997). Diastereoselective Michael Reactions of Azomethine Ylides to Chiral 4-Methyleneoxazolidin-5-ones: Synthesis of the Four Stereoisomers of 4-Benzamidopyroglutamate. Synlett, 1997(1), 100-102.

Scopus Eid


  • 2-s2.0-0002782416

Web Of Science Accession Number


Start Page


  • 100

End Page


  • 102

Volume


  • 1997

Issue


  • 1