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Development of a facile one-pot synthesis method for an ingestible pH sensitive actuator

Journal Article


Abstract


  • Edible devices are an emergent technology and in this paper the simplicity and efficacy that poly(acrylic acid)/calcium hydroxide possess in creating a pH sensitive ingestible actuator which responds to acidic environments such as gastric fluid is demonstrated. It was found that poly(acrylic acid)/calcium hydroxide hydrogels exhibit reversible actuation upon submerging in 0.1 M sodium citrate for 2 hours. Our results show that these hydrogels can restore their compressive stress to 0.19 ± 0.06 MPa, swelling ratio to 26 ± 2 and volume to 56% ± 3% of its original volume. This work offers new possibilities for developments in a variety of fields such as drug delivery, 4D printed materials, soft robotics and edible devices.

Publication Date


  • 2020

Citation


  • Keller, A., Warren, H., & Panhuis, M. I. H. (2020). Development of a facile one-pot synthesis method for an ingestible pH sensitive actuator. MRS Advances, 5(17), 881-889. doi:10.1557/adv.2019.370

Scopus Eid


  • 2-s2.0-85097891032

Start Page


  • 881

End Page


  • 889

Volume


  • 5

Issue


  • 17

Abstract


  • Edible devices are an emergent technology and in this paper the simplicity and efficacy that poly(acrylic acid)/calcium hydroxide possess in creating a pH sensitive ingestible actuator which responds to acidic environments such as gastric fluid is demonstrated. It was found that poly(acrylic acid)/calcium hydroxide hydrogels exhibit reversible actuation upon submerging in 0.1 M sodium citrate for 2 hours. Our results show that these hydrogels can restore their compressive stress to 0.19 ± 0.06 MPa, swelling ratio to 26 ± 2 and volume to 56% ± 3% of its original volume. This work offers new possibilities for developments in a variety of fields such as drug delivery, 4D printed materials, soft robotics and edible devices.

Publication Date


  • 2020

Citation


  • Keller, A., Warren, H., & Panhuis, M. I. H. (2020). Development of a facile one-pot synthesis method for an ingestible pH sensitive actuator. MRS Advances, 5(17), 881-889. doi:10.1557/adv.2019.370

Scopus Eid


  • 2-s2.0-85097891032

Start Page


  • 881

End Page


  • 889

Volume


  • 5

Issue


  • 17