Abstract
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3-(4', 6'-Dimethoxynaphthalen-1'-y1)propanoic acid (10) was transformed to 8-methoxy-5-(3'-oxo-buty1)-1, 2, 3, 4-tetrahydronaphthalene-2-carboxylic acid (8) and its 2-hydroxy derivative (9) by conventional synthetic reactions. Acid-catalysed cyclization of the derived diazomethyl ketones (23), (24) and (25) led to dienones (26), (27) and (28) which readily underwent base-catalysed 1, 4-conjugate addition to provide the hydroethanophenanthrenetriones (30), (31) and (32) respectively. �� 1981, CSIRO. All rights reserved.