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Synthesis of 4,4'-biimidazoles

Journal Article


Abstract


  • The palladium(0) catalysed coupling reaction of 4-iodo-1-triphenylmethylimidazole (7) or its 2-methyl analogue 8 afforded the 4,4'-biimidazoles 9 and 10, respectively. Treatment of these compounds with 60% aqueous trifluoroacetic acid gave 4,4'-biimidazole and 2,2'-dimethyl-4,4'-biimidazole as their bistrifluoroacetate salts 11 and 12, respectively.

Publication Date


  • 1994

Citation


  • Cliff, M. D., & Pyne, S. G. (1994). Synthesis of 4,4'-biimidazoles. Synthesis, (7), 681-682. doi:10.1055/s-1994-25544

Scopus Eid


  • 2-s2.0-0027983781

Web Of Science Accession Number


Start Page


  • 681

End Page


  • 682

Issue


  • 7

Abstract


  • The palladium(0) catalysed coupling reaction of 4-iodo-1-triphenylmethylimidazole (7) or its 2-methyl analogue 8 afforded the 4,4'-biimidazoles 9 and 10, respectively. Treatment of these compounds with 60% aqueous trifluoroacetic acid gave 4,4'-biimidazole and 2,2'-dimethyl-4,4'-biimidazole as their bistrifluoroacetate salts 11 and 12, respectively.

Publication Date


  • 1994

Citation


  • Cliff, M. D., & Pyne, S. G. (1994). Synthesis of 4,4'-biimidazoles. Synthesis, (7), 681-682. doi:10.1055/s-1994-25544

Scopus Eid


  • 2-s2.0-0027983781

Web Of Science Accession Number


Start Page


  • 681

End Page


  • 682

Issue


  • 7