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Diastereoselective addition of ¿-hydroxyalkyl and ¿-alkoxyalkyl radicals to chiral 4-methyleneoxazolidin-5-ones

Journal Article


Abstract


  • A method for preparing optically active homoserine derivatives via the photoinduced radical additions of alcohols and ethers to the chiral 4- methyleneoxazolidin-5-ones 1 and 2 has been achieved. These photoadducts, however, are readily prone to epimerization under the conditions required for their deprotection.

Publication Date


  • 1998

Citation


  • Pyne, S. G., & Schafer, K. (1998). Diastereoselective addition of ¿-hydroxyalkyl and ¿-alkoxyalkyl radicals to chiral 4-methyleneoxazolidin-5-ones. Tetrahedron, 54(21), 5709-5720. doi:10.1016/S0040-4020(98)00259-2

Scopus Eid


  • 2-s2.0-0032554849

Web Of Science Accession Number


Start Page


  • 5709

End Page


  • 5720

Volume


  • 54

Issue


  • 21

Abstract


  • A method for preparing optically active homoserine derivatives via the photoinduced radical additions of alcohols and ethers to the chiral 4- methyleneoxazolidin-5-ones 1 and 2 has been achieved. These photoadducts, however, are readily prone to epimerization under the conditions required for their deprotection.

Publication Date


  • 1998

Citation


  • Pyne, S. G., & Schafer, K. (1998). Diastereoselective addition of ¿-hydroxyalkyl and ¿-alkoxyalkyl radicals to chiral 4-methyleneoxazolidin-5-ones. Tetrahedron, 54(21), 5709-5720. doi:10.1016/S0040-4020(98)00259-2

Scopus Eid


  • 2-s2.0-0032554849

Web Of Science Accession Number


Start Page


  • 5709

End Page


  • 5720

Volume


  • 54

Issue


  • 21