Symptom Checklist-90 - Revised (SCL-90-R) scores of 209 undergraduate clients from a university-based psychology clinic were compared with those of 435 nonpatient undergraduates and with adult and adolescent norms. College student outpatients were similar to adult outpatients on the SCL-90-R. However, when compared with norms based on unscreened community samples, nonpatient undergraduates were, like adolescents, considerably more symptomatic than adults. Although nonpatient undergraduates were significantly less symptomatic than outpatient undergraduates, the two distributions overlapped considerably, which presents a high risk of misclassification. Comparison of the study samples with other published data supports the generalizability of these findings. The data's implications for the use of the SCL-90-R in evaluating symptomatology and the clinical significance of change in college students are discussed.