Skip to main content
placeholder image

Dynamic polymeric membrane structures for separation of proteins

Journal Article


Abstract


  • Novel dynamic polymeric membrane structures have been successfully prepared. These membranes have the necessary strength and pore size for use in electrochemically facilitated transport and separation of proteins. The transport of proteins can be electrochemically initiated and sustained or hindered when required. A high purity of human serum albumin (HSA) can be separated from a mixture containing equimolar concentrations of HSA and Myoglobin. Quartz crystal microbalance studies show that, in these cases of transport and separation, the overriding controlling factor was electrochemical control, although polymer/protein interactions do affect the transport fluxes.

Publication Date


  • 1997

Citation


  • Zhou, D., Wallace, G. G., & Too, C. O. (1997). Dynamic polymeric membrane structures for separation of proteins. Journal of Intelligent Material Systems and Structures, 8(12), 1052-1058. doi:10.1177/1045389X9700801206

Scopus Eid


  • 2-s2.0-0031319745

Start Page


  • 1052

End Page


  • 1058

Volume


  • 8

Issue


  • 12

Abstract


  • Novel dynamic polymeric membrane structures have been successfully prepared. These membranes have the necessary strength and pore size for use in electrochemically facilitated transport and separation of proteins. The transport of proteins can be electrochemically initiated and sustained or hindered when required. A high purity of human serum albumin (HSA) can be separated from a mixture containing equimolar concentrations of HSA and Myoglobin. Quartz crystal microbalance studies show that, in these cases of transport and separation, the overriding controlling factor was electrochemical control, although polymer/protein interactions do affect the transport fluxes.

Publication Date


  • 1997

Citation


  • Zhou, D., Wallace, G. G., & Too, C. O. (1997). Dynamic polymeric membrane structures for separation of proteins. Journal of Intelligent Material Systems and Structures, 8(12), 1052-1058. doi:10.1177/1045389X9700801206

Scopus Eid


  • 2-s2.0-0031319745

Start Page


  • 1052

End Page


  • 1058

Volume


  • 8

Issue


  • 12