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Hybrid Graphene/Conducting Polymer Strip Sensors for Sensitive and Selective Electrochemical Detection of Serotonin

Journal Article


Abstract


  • There is an urgent need for electrochemical sensor materials that exhibit electrochemically compliant properties while also retaining high durability under physiological conditions. Herein, we demonstrate a novel strip-style electrochemical sensor using reduced graphene oxide (rGO) and poly(ethylene dioxythiophene)/poly(styrene sulfonic acid) (PEDOT/PSS) nanocomposite films. The fabricated rGO-PEDOT/PSS sensor with and without nafion has shown an effective electrochemical response for both selectivity and sensitivity of the serotonin (5-hydroxytryptamine, 5-HT) neurotransmitter. The developed high-performance hybrid graphene/conducting polymer strip sensors are likely to find applications as chip electrochemical sensor devices for patients diagnosed with Alzheimer's disease.

Publication Date


  • 2019

Citation


  • Al-Graiti, W., Foroughi, J., Liu, Y., & Chen, J. (2019). Hybrid Graphene/Conducting Polymer Strip Sensors for Sensitive and Selective Electrochemical Detection of Serotonin. ACS Omega, 4(26), 22169-22177. doi:10.1021/acsomega.9b03456

Scopus Eid


  • 2-s2.0-85077011567

Start Page


  • 22169

End Page


  • 22177

Volume


  • 4

Issue


  • 26

Abstract


  • There is an urgent need for electrochemical sensor materials that exhibit electrochemically compliant properties while also retaining high durability under physiological conditions. Herein, we demonstrate a novel strip-style electrochemical sensor using reduced graphene oxide (rGO) and poly(ethylene dioxythiophene)/poly(styrene sulfonic acid) (PEDOT/PSS) nanocomposite films. The fabricated rGO-PEDOT/PSS sensor with and without nafion has shown an effective electrochemical response for both selectivity and sensitivity of the serotonin (5-hydroxytryptamine, 5-HT) neurotransmitter. The developed high-performance hybrid graphene/conducting polymer strip sensors are likely to find applications as chip electrochemical sensor devices for patients diagnosed with Alzheimer's disease.

Publication Date


  • 2019

Citation


  • Al-Graiti, W., Foroughi, J., Liu, Y., & Chen, J. (2019). Hybrid Graphene/Conducting Polymer Strip Sensors for Sensitive and Selective Electrochemical Detection of Serotonin. ACS Omega, 4(26), 22169-22177. doi:10.1021/acsomega.9b03456

Scopus Eid


  • 2-s2.0-85077011567

Start Page


  • 22169

End Page


  • 22177

Volume


  • 4

Issue


  • 26