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Reactive metabolite hypothesis for human senile cataract

Journal Article


Abstract


  • One of the research programs of the Australian Cataract Research Foundation (ACRF) is aimed at investigating the possibility that senile cataract both cortical and nuclear, may result from the interaction of reactive metabolites with proteins in the lens. In particular we are exploring the potential role of tryptophan metabolites for example, 3-hydroxyanthranilic acid, in this disease. This article examines briefly some aspects of this approach.

Publication Date


  • 1991

Citation


  • Truscott, R. J. W., Pyne, S. G., & Manthey, M. (1991). Reactive metabolite hypothesis for human senile cataract. Lens and Eye Toxicity Research, 8(2-3), 251-257.

Scopus Eid


  • 2-s2.0-0025837990

Web Of Science Accession Number


Start Page


  • 251

End Page


  • 257

Volume


  • 8

Issue


  • 2-3

Abstract


  • One of the research programs of the Australian Cataract Research Foundation (ACRF) is aimed at investigating the possibility that senile cataract both cortical and nuclear, may result from the interaction of reactive metabolites with proteins in the lens. In particular we are exploring the potential role of tryptophan metabolites for example, 3-hydroxyanthranilic acid, in this disease. This article examines briefly some aspects of this approach.

Publication Date


  • 1991

Citation


  • Truscott, R. J. W., Pyne, S. G., & Manthey, M. (1991). Reactive metabolite hypothesis for human senile cataract. Lens and Eye Toxicity Research, 8(2-3), 251-257.

Scopus Eid


  • 2-s2.0-0025837990

Web Of Science Accession Number


Start Page


  • 251

End Page


  • 257

Volume


  • 8

Issue


  • 2-3