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In vivo dosimetry and seed localization in prostate brachytherapy with permanent implants

Conference Paper


Abstract


  • This paper reports on the development of an interactive, intraoperative dose planning system for seed implant brachytherapy in cancer treatment This system involves in-vivo dosimetry and the ability to determine implanted seed positions. The first stage of this project is the development of a urethral alarm probe to measure the dose along the urethra during a prostate brachytherapy treatment procedure. Ultimately the system will be used to advise the physicians upon reaching a preset dose rate or dose after total seed decay in urethra during the seed placement. The second stage is the development of a method and instrumentation for in-vivo measurements of the location of implanted seeds in the same frame as for dose planning, and using these in intraoperative treatment planning. We have developed a silicon mini-detector and preamplifier/amplifier system to satisfy the spectroscopic requirements of the urethral probe. This technique will avoid complications related to overdosing the urethra and the rectum.

Publication Date


  • 2003

Citation


  • Rosenfeld, A. B., Brady, J., Braddock, T., Pervertailo, V., Cutajar, D. L., Lerch, M. L. F., . . . Zelefsky, M. (2003). In vivo dosimetry and seed localization in prostate brachytherapy with permanent implants. In IEEE Nuclear Science Symposium Conference Record Vol. 3 (pp. 1594-1598). doi:10.1109/nssmic.2003.1352182

Scopus Eid


  • 2-s2.0-19944427464

Start Page


  • 1594

End Page


  • 1598

Volume


  • 3

Abstract


  • This paper reports on the development of an interactive, intraoperative dose planning system for seed implant brachytherapy in cancer treatment This system involves in-vivo dosimetry and the ability to determine implanted seed positions. The first stage of this project is the development of a urethral alarm probe to measure the dose along the urethra during a prostate brachytherapy treatment procedure. Ultimately the system will be used to advise the physicians upon reaching a preset dose rate or dose after total seed decay in urethra during the seed placement. The second stage is the development of a method and instrumentation for in-vivo measurements of the location of implanted seeds in the same frame as for dose planning, and using these in intraoperative treatment planning. We have developed a silicon mini-detector and preamplifier/amplifier system to satisfy the spectroscopic requirements of the urethral probe. This technique will avoid complications related to overdosing the urethra and the rectum.

Publication Date


  • 2003

Citation


  • Rosenfeld, A. B., Brady, J., Braddock, T., Pervertailo, V., Cutajar, D. L., Lerch, M. L. F., . . . Zelefsky, M. (2003). In vivo dosimetry and seed localization in prostate brachytherapy with permanent implants. In IEEE Nuclear Science Symposium Conference Record Vol. 3 (pp. 1594-1598). doi:10.1109/nssmic.2003.1352182

Scopus Eid


  • 2-s2.0-19944427464

Start Page


  • 1594

End Page


  • 1598

Volume


  • 3