The behavior of fiber-reinforced polymer (FRP) tube reinforced concrete (FTRC) columns under different loading conditions was investigated in this study. Four groups of 16 specimens were cast and tested. Specimens in the first group (the reference group) were reinforced with longitudinal steel bars and steel helices (Group REF). Specimens in the second group were reinforced with intact glass FRP tubes (Group IT). Specimens in the third group were also reinforced with intact glass FRP tubes. In addition, polymer grid was embedded into the concrete cover to reduce the cover spalling (Group ITG). Specimens in the fourth group were reinforced with perforated glass FRP tubes (Group PT). One specimen from each group was tested under concentric loading, one under 25-mm eccentric loading, one under 50-mm eccentric loading, and one under four-point loading. Results from the experimental study show that FRP tubes significantly increase the load-carrying capacity and ductility of FTRC specimens. Group ITG specimens performed better than the other groups of specimens. Experimental and analytical interaction (P-M) diagrams also show the enhanced performance of FTRC specimens.