Skip to main content
placeholder image

Denisovan DNA in Late Pleistocene sediments from Baishiya Karst Cave on the Tibetan Plateau

Journal Article


Abstract


  • A late Middle Pleistocene mandible from Baishiya Karst Cave (BKC) on the Tibetan Plateau has been inferred to be from a Denisovan, an Asian hominin related to Neanderthals, on the basis of an amino acid substitution in its collagen. Here we describe the stratigraphy, chronology, and mitochondrial DNA extracted from the sediments in BKC. We recover Denisovan mitochondrial DNA from sediments deposited ~100 thousand and ~60 thousand years ago (ka) and possibly as recently as ~45 ka. The long-term occupation of BKC by Denisovans suggests that they may have adapted to life at high altitudes and may have contributed such adaptations to modern humans on the Tibetan Plateau.

Publication Date


  • 2020

Citation


  • Zhang, D., Xia, H., Chen, F., Li, B., Slon, V., Cheng, T., . . . Fu, Q. (2020). Denisovan DNA in Late Pleistocene sediments from Baishiya Karst Cave on the Tibetan Plateau. Science, 370(6516), 584-587. doi:10.1126/SCIENCE.ABB6320

Scopus Eid


  • 2-s2.0-85091940344

Web Of Science Accession Number


Start Page


  • 584

End Page


  • 587

Volume


  • 370

Issue


  • 6516

Abstract


  • A late Middle Pleistocene mandible from Baishiya Karst Cave (BKC) on the Tibetan Plateau has been inferred to be from a Denisovan, an Asian hominin related to Neanderthals, on the basis of an amino acid substitution in its collagen. Here we describe the stratigraphy, chronology, and mitochondrial DNA extracted from the sediments in BKC. We recover Denisovan mitochondrial DNA from sediments deposited ~100 thousand and ~60 thousand years ago (ka) and possibly as recently as ~45 ka. The long-term occupation of BKC by Denisovans suggests that they may have adapted to life at high altitudes and may have contributed such adaptations to modern humans on the Tibetan Plateau.

Publication Date


  • 2020

Citation


  • Zhang, D., Xia, H., Chen, F., Li, B., Slon, V., Cheng, T., . . . Fu, Q. (2020). Denisovan DNA in Late Pleistocene sediments from Baishiya Karst Cave on the Tibetan Plateau. Science, 370(6516), 584-587. doi:10.1126/SCIENCE.ABB6320

Scopus Eid


  • 2-s2.0-85091940344

Web Of Science Accession Number


Start Page


  • 584

End Page


  • 587

Volume


  • 370

Issue


  • 6516