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Thermal and hydrolytic degradation of electrospun fish gelatin membranes

Journal Article


Abstract


  • The thermal and hydrolytic degradation of electrospun gelatin membranes cross-linked with glutaraldehyde in vapor phase has been studied. In vitro degradation of gelatin membranes was evaluated in phosphate buffer saline solution at 37 C. After 15 days under these conditions, a weight loss of 68% was observed, attributed to solvation and depolymerization of the main polymeric chains. Thermal degradation kinetics of the gelatin raw material and as-spun electrospun membranes showed that the electrospinning processing conditions do not influence polymer degradation. However, for cross-linked samples a decrease in the activation energy was observed, associated with the effect of glutaraldehyde cross-linking reaction in the inter- and intra-molecular hydrogen bonds of the protein. It is also shown that the electrospinning process does not affect the formation of the helical structure of gelatin chains. © 2013 Elsevier Ltd. All rights reserved.

UOW Authors


  •   Correia, Daniela M. (external author)
  •   Padrão, J (external author)
  •   Rodrigues, L R. (external author)
  •   Dourado, F (external author)
  •   Lanceros-Méndez, Senentxu (external author)
  •   Gomes da Silva Sencadas, Vitor

Publication Date


  • 2013

Citation


  • Correia, D. M., Padrão, J., Rodrigues, L. R., Dourado, F., Lanceros-Méndez, S. & Sencadas, V. (2013). Thermal and hydrolytic degradation of electrospun fish gelatin membranes. Polymer Testing, 32 (5), 995-1000.

Scopus Eid


  • 2-s2.0-84879234352

Ro Metadata Url


  • http://ro.uow.edu.au/eispapers/3689

Number Of Pages


  • 5

Start Page


  • 995

End Page


  • 1000

Volume


  • 32

Issue


  • 5

Abstract


  • The thermal and hydrolytic degradation of electrospun gelatin membranes cross-linked with glutaraldehyde in vapor phase has been studied. In vitro degradation of gelatin membranes was evaluated in phosphate buffer saline solution at 37 C. After 15 days under these conditions, a weight loss of 68% was observed, attributed to solvation and depolymerization of the main polymeric chains. Thermal degradation kinetics of the gelatin raw material and as-spun electrospun membranes showed that the electrospinning processing conditions do not influence polymer degradation. However, for cross-linked samples a decrease in the activation energy was observed, associated with the effect of glutaraldehyde cross-linking reaction in the inter- and intra-molecular hydrogen bonds of the protein. It is also shown that the electrospinning process does not affect the formation of the helical structure of gelatin chains. © 2013 Elsevier Ltd. All rights reserved.

UOW Authors


  •   Correia, Daniela M. (external author)
  •   Padrão, J (external author)
  •   Rodrigues, L R. (external author)
  •   Dourado, F (external author)
  •   Lanceros-Méndez, Senentxu (external author)
  •   Gomes da Silva Sencadas, Vitor

Publication Date


  • 2013

Citation


  • Correia, D. M., Padrão, J., Rodrigues, L. R., Dourado, F., Lanceros-Méndez, S. & Sencadas, V. (2013). Thermal and hydrolytic degradation of electrospun fish gelatin membranes. Polymer Testing, 32 (5), 995-1000.

Scopus Eid


  • 2-s2.0-84879234352

Ro Metadata Url


  • http://ro.uow.edu.au/eispapers/3689

Number Of Pages


  • 5

Start Page


  • 995

End Page


  • 1000

Volume


  • 32

Issue


  • 5