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Bioactive glycosides from the African medicinal plant Boerhavia erecta L.

Journal Article


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Abstract


  • Phytochemical studies of the previously unexplored stem of Boerhavia erecta from Burkina Faso, resulted in the isolation of an unreported glycoside 4, 2,3-dihydroxypropylbenzoate-3-O-β-[4″-methoxy] glucuronide as well as seven known glycosides (1–3, 5–8). The major isolate 5 and 8 indicated a significant inhibition against HIV integrase (IC50 10 and 22 μg/mL, respectively). The extracts and isolates were also tested for anti-malarial activity, but insignificant activity was observed.

Authors


  •   Nugraha, Ari Satia (external author)
  •   Hilou, Adama (external author)
  •   Vandegraaff, Nicholas (external author)
  •   Rhodes, David I. (external author)
  •   Haritakun, Rachada (external author)
  •   Keller, Paul A.

Publication Date


  • 2015

Citation


  • Nugraha, A. S., Hilou, A., Vandegraaff, N., Rhodes, D. I., Haritakun, R. & Keller, P. A. (2015). Bioactive glycosides from the African medicinal plant Boerhavia erecta L.. Natural Product Research, 29 (20), 1954-1958.

Scopus Eid


  • 2-s2.0-84941598853

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=4206&context=smhpapers

Ro Metadata Url


  • http://ro.uow.edu.au/smhpapers/3183

Number Of Pages


  • 4

Start Page


  • 1954

End Page


  • 1958

Volume


  • 29

Issue


  • 20

Abstract


  • Phytochemical studies of the previously unexplored stem of Boerhavia erecta from Burkina Faso, resulted in the isolation of an unreported glycoside 4, 2,3-dihydroxypropylbenzoate-3-O-β-[4″-methoxy] glucuronide as well as seven known glycosides (1–3, 5–8). The major isolate 5 and 8 indicated a significant inhibition against HIV integrase (IC50 10 and 22 μg/mL, respectively). The extracts and isolates were also tested for anti-malarial activity, but insignificant activity was observed.

Authors


  •   Nugraha, Ari Satia (external author)
  •   Hilou, Adama (external author)
  •   Vandegraaff, Nicholas (external author)
  •   Rhodes, David I. (external author)
  •   Haritakun, Rachada (external author)
  •   Keller, Paul A.

Publication Date


  • 2015

Citation


  • Nugraha, A. S., Hilou, A., Vandegraaff, N., Rhodes, D. I., Haritakun, R. & Keller, P. A. (2015). Bioactive glycosides from the African medicinal plant Boerhavia erecta L.. Natural Product Research, 29 (20), 1954-1958.

Scopus Eid


  • 2-s2.0-84941598853

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=4206&context=smhpapers

Ro Metadata Url


  • http://ro.uow.edu.au/smhpapers/3183

Number Of Pages


  • 4

Start Page


  • 1954

End Page


  • 1958

Volume


  • 29

Issue


  • 20