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An electrospun strong PCL/PU composite vascular graft with mechanical anisotropy and cyclic stability

Journal Article


Abstract


  • A strong PCL/PU (polycaprolactone/polyurethane) vascular graft was fabricated using electrospinning. By regulating the content of PCL, the composite scaffolds show an obvious mechanical enhancement with strength up to 69.95 MPa. Furthermore, the scaffolds exhibit high porosity, mechanical anisotropy, cell compatibility and cycle performance, which are important for tissue engineering applications.

Authors


  •   Wang, Nu (external author)
  •   Zhao, Yong (external author)
  •   Guo, Fengyun (external author)
  •   Wang, Li (external author)
  •   Hou, Lanlan (external author)
  •   Ma, Lan (external author)
  •   Chen, Yuee (external author)
  •   Fan, Bingbing (external author)
  •   Liu, Jing (external author)

Publication Date


  • 2015

Citation


  • Guo, F., Wang, N., Wang, L., Hou, L., Ma, L., Liu, J., Chen, Y., Fan, B. & Zhao, Y. (2015). An electrospun strong PCL/PU composite vascular graft with mechanical anisotropy and cyclic stability. Journal of Materials Chemistry A, 3 (9), 4782-4787.

Scopus Eid


  • 2-s2.0-84923239481

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/1460

Has Global Citation Frequency


Number Of Pages


  • 5

Start Page


  • 4782

End Page


  • 4787

Volume


  • 3

Issue


  • 9

Abstract


  • A strong PCL/PU (polycaprolactone/polyurethane) vascular graft was fabricated using electrospinning. By regulating the content of PCL, the composite scaffolds show an obvious mechanical enhancement with strength up to 69.95 MPa. Furthermore, the scaffolds exhibit high porosity, mechanical anisotropy, cell compatibility and cycle performance, which are important for tissue engineering applications.

Authors


  •   Wang, Nu (external author)
  •   Zhao, Yong (external author)
  •   Guo, Fengyun (external author)
  •   Wang, Li (external author)
  •   Hou, Lanlan (external author)
  •   Ma, Lan (external author)
  •   Chen, Yuee (external author)
  •   Fan, Bingbing (external author)
  •   Liu, Jing (external author)

Publication Date


  • 2015

Citation


  • Guo, F., Wang, N., Wang, L., Hou, L., Ma, L., Liu, J., Chen, Y., Fan, B. & Zhao, Y. (2015). An electrospun strong PCL/PU composite vascular graft with mechanical anisotropy and cyclic stability. Journal of Materials Chemistry A, 3 (9), 4782-4787.

Scopus Eid


  • 2-s2.0-84923239481

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/1460

Has Global Citation Frequency


Number Of Pages


  • 5

Start Page


  • 4782

End Page


  • 4787

Volume


  • 3

Issue


  • 9