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Factors influencing serum caffeine concentrations following caffeine ingestion

Journal Article


Abstract


  • Objectives

    To determine whether differences in training status, body composition and/or habitual caffeine intake influenced serum caffeine concentrations following caffeine ingestion.

    Design

    Single-blind.

    Methods

    Trained cyclists/triathletes (n = 14) and active (n = 14) males consumed 6 mg kg−1 anhydrous caffeine. Peak, total and time to peak serum caffeine concentrations were determined from venous blood samples at baseline and 6 time-points over 4 h following intake. Body composition was assessed by dual energy X-ray absorptiometry and habitual caffeine intake by a questionnaire.

    Results

    Trained cyclists/triathletes had 16% lower peak caffeine concentrations following caffeine ingestion compared to active individuals, although this was not statistically significant (p = 0.066). There was no significant difference between trained cyclists/triathletes and active males in total (p = 0.131) or time to peak (p = 0.249) serum caffeine concentrations. Fat mass was significantly associated with total (r = 0.427, p = 0.038) but not peak (r = 0.343, p = 0.101) or time to peak serum caffeine concentration (β = 0.00008, p = 0.961). There were no associations between habitual caffeine intake and peak, total or time to peak serum caffeine concentrations.

    Conclusions

    Following caffeine ingestion three findings from the study were evident: (1) endurance-trained athletes trended towards lower peak caffeine concentrations compared to active males; (2) higher fat mass was associated with higher concentrations of caffeine in the blood over 4 h, and (3) habitual caffeine intake does not appear to influence serum caffeine concentrations. Identification of the optimal conditions to ensure peak availability of caffeine within the blood and/or overcoming some of the variation in how individuals respond to caffeine requires consideration of the training status and body composition of the athlete.

UOW Authors


  •   Bolam, Kate A. (external author)
  •   Jenkins, David G. (external author)
  •   Skinner, Tina L. (external author)
  •   Leveritt, Michael D. (external author)
  •   Mcgorm, Alastair (external author)
  •   Coombes, Jeff S. (external author)
  •   Taaffe, Dennis R. (external author)

Publication Date


  • 2014

Citation


  • Skinner, T. L., Jenkins, D. G., Leveritt, M. D., Mcgorm, A., Bolam, K. A., Coombes, J. S. & Taaffe, D. R. (2014). Factors influencing serum caffeine concentrations following caffeine ingestion. Journal of Science and Medicine in Sport, 17 (5), 516-520.

Scopus Eid


  • 2-s2.0-84906317050

Ro Metadata Url


  • http://ro.uow.edu.au/smhpapers/2543

Has Global Citation Frequency


Number Of Pages


  • 4

Start Page


  • 516

End Page


  • 520

Volume


  • 17

Issue


  • 5

Abstract


  • Objectives

    To determine whether differences in training status, body composition and/or habitual caffeine intake influenced serum caffeine concentrations following caffeine ingestion.

    Design

    Single-blind.

    Methods

    Trained cyclists/triathletes (n = 14) and active (n = 14) males consumed 6 mg kg−1 anhydrous caffeine. Peak, total and time to peak serum caffeine concentrations were determined from venous blood samples at baseline and 6 time-points over 4 h following intake. Body composition was assessed by dual energy X-ray absorptiometry and habitual caffeine intake by a questionnaire.

    Results

    Trained cyclists/triathletes had 16% lower peak caffeine concentrations following caffeine ingestion compared to active individuals, although this was not statistically significant (p = 0.066). There was no significant difference between trained cyclists/triathletes and active males in total (p = 0.131) or time to peak (p = 0.249) serum caffeine concentrations. Fat mass was significantly associated with total (r = 0.427, p = 0.038) but not peak (r = 0.343, p = 0.101) or time to peak serum caffeine concentration (β = 0.00008, p = 0.961). There were no associations between habitual caffeine intake and peak, total or time to peak serum caffeine concentrations.

    Conclusions

    Following caffeine ingestion three findings from the study were evident: (1) endurance-trained athletes trended towards lower peak caffeine concentrations compared to active males; (2) higher fat mass was associated with higher concentrations of caffeine in the blood over 4 h, and (3) habitual caffeine intake does not appear to influence serum caffeine concentrations. Identification of the optimal conditions to ensure peak availability of caffeine within the blood and/or overcoming some of the variation in how individuals respond to caffeine requires consideration of the training status and body composition of the athlete.

UOW Authors


  •   Bolam, Kate A. (external author)
  •   Jenkins, David G. (external author)
  •   Skinner, Tina L. (external author)
  •   Leveritt, Michael D. (external author)
  •   Mcgorm, Alastair (external author)
  •   Coombes, Jeff S. (external author)
  •   Taaffe, Dennis R. (external author)

Publication Date


  • 2014

Citation


  • Skinner, T. L., Jenkins, D. G., Leveritt, M. D., Mcgorm, A., Bolam, K. A., Coombes, J. S. & Taaffe, D. R. (2014). Factors influencing serum caffeine concentrations following caffeine ingestion. Journal of Science and Medicine in Sport, 17 (5), 516-520.

Scopus Eid


  • 2-s2.0-84906317050

Ro Metadata Url


  • http://ro.uow.edu.au/smhpapers/2543

Has Global Citation Frequency


Number Of Pages


  • 4

Start Page


  • 516

End Page


  • 520

Volume


  • 17

Issue


  • 5