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Synthesis of mono and bis[60]fullerene-based dicationic peptoids

Journal Article


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Abstract


  • Increasing numbers of biological applications of fullerenyl amino acids and their derivatives encouraged us to synthesise [60]fullerenyldihydropyrrole peptides, prepared from the coupling of mono- and bis[60]fullerenyldihydropyrrolecarboxylic acids 4, 5 and 41 with presynthesised peptides 13, 16, 24, 28, 29 and 46. The resulting hydrophobic scaffolded di- and tetra-cationic derivatives were tested against Staphylococcus aureus NCTC 6571 and Escherichia coli NCTC 10418. The synthesis, characterisation and biological results are discussed in this paper.

Authors


  •   Jennepalli, Sreenu (external author)
  •   Hammer, Katherine A. (external author)
  •   Riley, Thomas V. (external author)
  •   Pyne, Stephen G.
  •   Keller, Paul A.

Publication Date


  • 2015

Citation


  • Jennepalli, S., Hammer, K. A., Riley, T. V., Pyne, S. G. & Keller, P. A. (2015). Synthesis of mono and bis[60]fullerene-based dicationic peptoids. European Journal of Organic Chemistry, 2015 (1), 195-201.

Scopus Eid


  • 2-s2.0-84919332034

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=3483&context=smhpapers

Ro Metadata Url


  • http://ro.uow.edu.au/smhpapers/2464

Number Of Pages


  • 6

Start Page


  • 195

End Page


  • 201

Volume


  • 2015

Issue


  • 1

Abstract


  • Increasing numbers of biological applications of fullerenyl amino acids and their derivatives encouraged us to synthesise [60]fullerenyldihydropyrrole peptides, prepared from the coupling of mono- and bis[60]fullerenyldihydropyrrolecarboxylic acids 4, 5 and 41 with presynthesised peptides 13, 16, 24, 28, 29 and 46. The resulting hydrophobic scaffolded di- and tetra-cationic derivatives were tested against Staphylococcus aureus NCTC 6571 and Escherichia coli NCTC 10418. The synthesis, characterisation and biological results are discussed in this paper.

Authors


  •   Jennepalli, Sreenu (external author)
  •   Hammer, Katherine A. (external author)
  •   Riley, Thomas V. (external author)
  •   Pyne, Stephen G.
  •   Keller, Paul A.

Publication Date


  • 2015

Citation


  • Jennepalli, S., Hammer, K. A., Riley, T. V., Pyne, S. G. & Keller, P. A. (2015). Synthesis of mono and bis[60]fullerene-based dicationic peptoids. European Journal of Organic Chemistry, 2015 (1), 195-201.

Scopus Eid


  • 2-s2.0-84919332034

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=3483&context=smhpapers

Ro Metadata Url


  • http://ro.uow.edu.au/smhpapers/2464

Number Of Pages


  • 6

Start Page


  • 195

End Page


  • 201

Volume


  • 2015

Issue


  • 1