3-dimensional (3D) fabricated polymer based drug delivery systems

Journal Article


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Abstract


  • Drug delivery from 3-dimensional (3D) structures is a rapidly growing area of research. It is essential to achieve structures wherein drug stability is ensured, the drug loading capacity is appropriate and the desired controlled release profile can be attained. Attention must also be paid to the development of appropriate fabrication machinery that allows 3D drug delivery systems (DDS) to be produced in a simple, reliable and reproducible manner. The range of fabrication methods currently being used to form 3D DDSs include electrospinning (solution and melt), wet-spinning and printing (3-dimensional). The use of these techniques enables production of DDSs from the macro-scale down to the nano-scale. This article reviews progress in these fabrication techniques to form DDSs that possess desirable drug delivery kinetics for a wide range of applications.

Publication Date


  • 2014

Citation


  • Moulton, S. E. & Wallace, G. G. (2014). 3-dimensional (3D) fabricated polymer based drug delivery systems. Journal of Controlled Release, 193 27-34.

Scopus Eid


  • 2-s2.0-84906376690

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=2240&context=aiimpapers

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/1239

Has Global Citation Frequency


Number Of Pages


  • 7

Start Page


  • 27

End Page


  • 34

Volume


  • 193

Place Of Publication


  • Netherlands

Abstract


  • Drug delivery from 3-dimensional (3D) structures is a rapidly growing area of research. It is essential to achieve structures wherein drug stability is ensured, the drug loading capacity is appropriate and the desired controlled release profile can be attained. Attention must also be paid to the development of appropriate fabrication machinery that allows 3D drug delivery systems (DDS) to be produced in a simple, reliable and reproducible manner. The range of fabrication methods currently being used to form 3D DDSs include electrospinning (solution and melt), wet-spinning and printing (3-dimensional). The use of these techniques enables production of DDSs from the macro-scale down to the nano-scale. This article reviews progress in these fabrication techniques to form DDSs that possess desirable drug delivery kinetics for a wide range of applications.

Publication Date


  • 2014

Citation


  • Moulton, S. E. & Wallace, G. G. (2014). 3-dimensional (3D) fabricated polymer based drug delivery systems. Journal of Controlled Release, 193 27-34.

Scopus Eid


  • 2-s2.0-84906376690

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=2240&context=aiimpapers

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/1239

Has Global Citation Frequency


Number Of Pages


  • 7

Start Page


  • 27

End Page


  • 34

Volume


  • 193

Place Of Publication


  • Netherlands