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The generation of GLP-grade human embryonic stem cell banks from four clinical-grade cell lines for preclinical research

Journal Article


Abstract


  • The Singapore Stem Cell Bank has generated human embryonic stem cell banks from clinical-grade cell lines ESI-017, ESI-035, ESI-049, and ESI-053. All banks were prepared and characterized according to principles of Good Laboratory Practice for quality assurance. Importantly, each cell line has clearly documented and approved ethical provenance and meets recognized standards for performance and safety. The banks are intended to facilitate the translation of stem cell research to clinical medicine by enabling early phase research and development with high-quality, low-cost cells that are also available as clinical-grade stocks.

Authors


  •   Sivarajah, Shirani (external author)
  •   Raj, Grace S. (external author)
  •   Mathews, Adam Joshua Varughese (external author)
  •   Sahib, Norliza Binte Esmail (external author)
  •   Hwang, Wei S. (external author)
  •   Crook, Jeremy M.

Publication Date


  • 2010

Citation


  • Sivarajah, S., Raj, G. Selva., Mathews, A. Varughese., Sahib, N. Binte Esmail., Hwang, W. Sek. & Crook, J. Micah. (2010). The generation of GLP-grade human embryonic stem cell banks from four clinical-grade cell lines for preclinical research. In Vitro Cellular and Developmental Biology: Animal, 46 (3-4), 210-216.

Scopus Eid


  • 2-s2.0-77952092730

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/1185

Has Global Citation Frequency


Number Of Pages


  • 6

Start Page


  • 210

End Page


  • 216

Volume


  • 46

Issue


  • 3-4

Place Of Publication


  • Germany

Abstract


  • The Singapore Stem Cell Bank has generated human embryonic stem cell banks from clinical-grade cell lines ESI-017, ESI-035, ESI-049, and ESI-053. All banks were prepared and characterized according to principles of Good Laboratory Practice for quality assurance. Importantly, each cell line has clearly documented and approved ethical provenance and meets recognized standards for performance and safety. The banks are intended to facilitate the translation of stem cell research to clinical medicine by enabling early phase research and development with high-quality, low-cost cells that are also available as clinical-grade stocks.

Authors


  •   Sivarajah, Shirani (external author)
  •   Raj, Grace S. (external author)
  •   Mathews, Adam Joshua Varughese (external author)
  •   Sahib, Norliza Binte Esmail (external author)
  •   Hwang, Wei S. (external author)
  •   Crook, Jeremy M.

Publication Date


  • 2010

Citation


  • Sivarajah, S., Raj, G. Selva., Mathews, A. Varughese., Sahib, N. Binte Esmail., Hwang, W. Sek. & Crook, J. Micah. (2010). The generation of GLP-grade human embryonic stem cell banks from four clinical-grade cell lines for preclinical research. In Vitro Cellular and Developmental Biology: Animal, 46 (3-4), 210-216.

Scopus Eid


  • 2-s2.0-77952092730

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/1185

Has Global Citation Frequency


Number Of Pages


  • 6

Start Page


  • 210

End Page


  • 216

Volume


  • 46

Issue


  • 3-4

Place Of Publication


  • Germany