Robust biopolymer based ionic-covalent entanglement hydrogels with reversible mechanical behaviour

Journal Article


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Abstract


  • Emerging applications of hydrogels such as soft robotics and cartilage tissue scaffolds require hydrogels with enhanced mechanical performance. We report the development of a robust biopolymer based ionic–covalent entanglement network hydrogel made from calcium cross-linked gellan gum and genipin cross-linked gelatin. The ratio of the two polymers and the cross-linker concentrations significantly affected the mechanical characteristics of the hydrogels. Hydrogels with optimized composition exhibited compressive fracture stress and work of extension values of up to 1.1 ± 0.2 MPa and 230 ± 40 kJ m−3 for swelling ratios of 37.4 ± 0.6 and 19 ± 1, respectively. The compressive and tensile mechanical properties, swelling behavior (including leachage), pH sensitivity and homogeneity are discussed in detail. Fully swollen hydrogels (swelling ratio of 37.4 ± 0.6) were able to recover 95 ± 2% and 82 ± 7% of their energy dissipation (hysteresis) at 37 °C after reloading to either constant stress (150 kPa) or constant strain (50%), respectively.

Publication Date


  • 2014

Citation


  • Kirchmajer, D. M. & in het Panhuis, M. (2014). Robust biopolymer based ionic-covalent entanglement hydrogels with reversible mechanical behaviour. Journal of Materials Chemistry B, 2 (29), 4694-4702.

Scopus Eid


  • 2-s2.0-84903787480

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=3410&context=smhpapers

Ro Metadata Url


  • http://ro.uow.edu.au/smhpapers/2391

Number Of Pages


  • 8

Start Page


  • 4694

End Page


  • 4702

Volume


  • 2

Issue


  • 29

Abstract


  • Emerging applications of hydrogels such as soft robotics and cartilage tissue scaffolds require hydrogels with enhanced mechanical performance. We report the development of a robust biopolymer based ionic–covalent entanglement network hydrogel made from calcium cross-linked gellan gum and genipin cross-linked gelatin. The ratio of the two polymers and the cross-linker concentrations significantly affected the mechanical characteristics of the hydrogels. Hydrogels with optimized composition exhibited compressive fracture stress and work of extension values of up to 1.1 ± 0.2 MPa and 230 ± 40 kJ m−3 for swelling ratios of 37.4 ± 0.6 and 19 ± 1, respectively. The compressive and tensile mechanical properties, swelling behavior (including leachage), pH sensitivity and homogeneity are discussed in detail. Fully swollen hydrogels (swelling ratio of 37.4 ± 0.6) were able to recover 95 ± 2% and 82 ± 7% of their energy dissipation (hysteresis) at 37 °C after reloading to either constant stress (150 kPa) or constant strain (50%), respectively.

Publication Date


  • 2014

Citation


  • Kirchmajer, D. M. & in het Panhuis, M. (2014). Robust biopolymer based ionic-covalent entanglement hydrogels with reversible mechanical behaviour. Journal of Materials Chemistry B, 2 (29), 4694-4702.

Scopus Eid


  • 2-s2.0-84903787480

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=3410&context=smhpapers

Ro Metadata Url


  • http://ro.uow.edu.au/smhpapers/2391

Number Of Pages


  • 8

Start Page


  • 4694

End Page


  • 4702

Volume


  • 2

Issue


  • 29