Skip to main content

Effects of methamphetamine and its primary human metabolite, p-hydroxymethamphetamine, on the development of the Australian blowfly Calliphora stygia

Journal Article


Abstract


  • The larvae of necrophagous fly species are used as forensic tools for the determination of the minimum postmortem interval (PMI). However, any ingested drugs in corpses may affect larval development, thus leading to incorrect estimates of the period of infestation. This study investigated the effects of methamphetamine and its metabolite, p-hydroxymethamphetamine, on the forensically important Australian blowfly Calliphora stygia. It was found that the presence of the drugs significantly accelerated larval growth and increased the size of all life stages. Furthermore, drug-exposed samples remained as pupae for up to 78 h longer than controls. These findings suggest that estimates of the minimum PMI of methamphetamine-dosed corpses could be incorrect if the altered growth of C. stygia is not considered. Different temperatures, drug concentrations and substrate types are also likely to affect the development of this blowfly. Pending further research, the application of C. stygia to the entomological analysis of methamphetamine-related fatalities should be appropriately qualified.

Publication Date


  • 2014

Citation


  • Mullany, C., Keller, P. A., Nugraha, A. S. & Wallman, J. F. (2014). Effects of methamphetamine and its primary human metabolite, p-hydroxymethamphetamine, on the development of the Australian blowfly Calliphora stygia. Forensic Science International, 241 102-111.

Scopus Eid


  • 2-s2.0-84901797336

Ro Metadata Url


  • http://ro.uow.edu.au/smhpapers/2079

Has Global Citation Frequency


Number Of Pages


  • 9

Start Page


  • 102

End Page


  • 111

Volume


  • 241

Place Of Publication


  • Ireland

Abstract


  • The larvae of necrophagous fly species are used as forensic tools for the determination of the minimum postmortem interval (PMI). However, any ingested drugs in corpses may affect larval development, thus leading to incorrect estimates of the period of infestation. This study investigated the effects of methamphetamine and its metabolite, p-hydroxymethamphetamine, on the forensically important Australian blowfly Calliphora stygia. It was found that the presence of the drugs significantly accelerated larval growth and increased the size of all life stages. Furthermore, drug-exposed samples remained as pupae for up to 78 h longer than controls. These findings suggest that estimates of the minimum PMI of methamphetamine-dosed corpses could be incorrect if the altered growth of C. stygia is not considered. Different temperatures, drug concentrations and substrate types are also likely to affect the development of this blowfly. Pending further research, the application of C. stygia to the entomological analysis of methamphetamine-related fatalities should be appropriately qualified.

Publication Date


  • 2014

Citation


  • Mullany, C., Keller, P. A., Nugraha, A. S. & Wallman, J. F. (2014). Effects of methamphetamine and its primary human metabolite, p-hydroxymethamphetamine, on the development of the Australian blowfly Calliphora stygia. Forensic Science International, 241 102-111.

Scopus Eid


  • 2-s2.0-84901797336

Ro Metadata Url


  • http://ro.uow.edu.au/smhpapers/2079

Has Global Citation Frequency


Number Of Pages


  • 9

Start Page


  • 102

End Page


  • 111

Volume


  • 241

Place Of Publication


  • Ireland