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Panoptes: Calibration of a dosimetry system for eye brachytherapy

Journal Article


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Abstract


  • Intraocular cancer is a serious threat to the lives of those that suffer from it. Dosimetry for eye brachytherapy presents a significant challenge due to the inherently steep dose gradients that are needed to treat such small tumours in close proximity to sensitive normal structures. This issue is addressed by providing much needed quality assurance to eye brachytherapy, a novel volumetric dosimetry system, called Panoptes was developed. This study focuses on the preliminary characterisation and calibration of the system. Using ion beam facilities, the custom, pixelated silicon detector of Panoptes was shown to have good charge collection uniformity and a well defined sensitive volume. Flat-field calibration was conducted on the device using a 250 kVp orthovoltage beam. Finally, the detector and phantom were simulated with Monte Carlo in Geant4, to create water equivalent dose correction factors for each pixel across a range of angles. © 2014 Elsevier Ltd.

UOW Authors


  •   Weaver, Michael R. (external author)
  •   Petasecca, Marco
  •   Cutajar, Dean
  •   Lerch, Michael
  •   De Geronimo, Gianluigi (external author)
  •   Pinelli, Donald A. (external author)
  •   Cullen, Ashley (external author)
  •   Prokopovich, Dale (external author)
  •   Perevertaylo, Vladimir L. (external author)
  •   Rosenfeld, Anatoly B.

Publication Date


  • 2014

Citation


  • Weaver, M., Petasecca, M., Cutajar, D. L., Lerch, M. L. F., De Geronimo, G., Pinelli, D. A., Cullen, A. J., Prokopovich, D. A., Perevertaylo, V. L. & Rosenfeld, A. B. (2014). Panoptes: Calibration of a dosimetry system for eye brachytherapy. Radiation Measurements, 71 310-314.

Scopus Eid


  • 2-s2.0-85027956421

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=3833&context=eispapers

Ro Metadata Url


  • http://ro.uow.edu.au/eispapers/2824

Has Global Citation Frequency


Number Of Pages


  • 4

Start Page


  • 310

End Page


  • 314

Volume


  • 71

Place Of Publication


  • United Kingdom

Abstract


  • Intraocular cancer is a serious threat to the lives of those that suffer from it. Dosimetry for eye brachytherapy presents a significant challenge due to the inherently steep dose gradients that are needed to treat such small tumours in close proximity to sensitive normal structures. This issue is addressed by providing much needed quality assurance to eye brachytherapy, a novel volumetric dosimetry system, called Panoptes was developed. This study focuses on the preliminary characterisation and calibration of the system. Using ion beam facilities, the custom, pixelated silicon detector of Panoptes was shown to have good charge collection uniformity and a well defined sensitive volume. Flat-field calibration was conducted on the device using a 250 kVp orthovoltage beam. Finally, the detector and phantom were simulated with Monte Carlo in Geant4, to create water equivalent dose correction factors for each pixel across a range of angles. © 2014 Elsevier Ltd.

UOW Authors


  •   Weaver, Michael R. (external author)
  •   Petasecca, Marco
  •   Cutajar, Dean
  •   Lerch, Michael
  •   De Geronimo, Gianluigi (external author)
  •   Pinelli, Donald A. (external author)
  •   Cullen, Ashley (external author)
  •   Prokopovich, Dale (external author)
  •   Perevertaylo, Vladimir L. (external author)
  •   Rosenfeld, Anatoly B.

Publication Date


  • 2014

Citation


  • Weaver, M., Petasecca, M., Cutajar, D. L., Lerch, M. L. F., De Geronimo, G., Pinelli, D. A., Cullen, A. J., Prokopovich, D. A., Perevertaylo, V. L. & Rosenfeld, A. B. (2014). Panoptes: Calibration of a dosimetry system for eye brachytherapy. Radiation Measurements, 71 310-314.

Scopus Eid


  • 2-s2.0-85027956421

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=3833&context=eispapers

Ro Metadata Url


  • http://ro.uow.edu.au/eispapers/2824

Has Global Citation Frequency


Number Of Pages


  • 4

Start Page


  • 310

End Page


  • 314

Volume


  • 71

Place Of Publication


  • United Kingdom