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Short-term outcomes of mothers and newborn infants with comorbid psychiatric disorders and drug dependency

Journal Article


Abstract


  • Objectives: The aim of the present study was to determine the characteristics and short-term outcomes of mother–infant pairs with comorbid drug dependency and psychiatric disorders.

    Methods: A population-based retrospective chart review was carried out of 879 drug-dependent mother and infant pairs in New South Wales (NSW) and the Australian Capital Territory (ACT) who delivered between 1 January and 31 December 2004.

    Results: Psychiatric comorbidity (dual diagnosis, DD) was identified in 396 (45%) of the 879 drug-dependent women. DSM-IV depression (79%), followed by anxiety (20%), was most prevalent. DD women were more likely to use amphetamines (29% vs 18%, p < 0.05), less likely to use opiates (42% vs 51%, p < 0.05) and to have had no antenatal care (24% vs 8%, p < 0.05). They also had more previous pregnancies (4, range = 2–5 vs 3, range = 2–5, p < 0.05) and domestic violence (29% vs 14%, p < 0.05) was more common. DD infants were less likely to be admitted to a nursery (47% vs 55%, p < 0.05). Withdrawal scores were similar (maximum median Finnegan scores = 4 (interquartile range = 3–8) vs 10 (interquartile range = 7–12, p = 0.30) but fewer needed withdrawal medication (19% vs 27%, p < 0.05). Maternal psychotropic agents did not worsen the severity of neonatal withdrawal.

    Conclusions: Psychiatric comorbidity, especially depression, is common and affects almost half of drug-using mothers. Antenatal care, drug use and social outcomes are worse for DD mothers and their infants. It is recommended that all drug-using women be assessed antenatally for psychosocial disorders so that timely mental health intervention can be offered, if required.

Authors


  •   Oei, Ju Lee (external author)
  •   Abdel-Latif, Mohamed E. (external author)
  •   Craig, Fiona (external author)
  •   Kee, Aivy (external author)
  •   Austin, Marie-Paule (external author)
  •   Lui, Kei (external author)
  •   Wright, Ian M. R.

Publication Date


  • 2009

Citation


  • Oei, J., Abdel-Latif, M. E., Craig, F., Kee, A., Austin, M., Lui, K. & Wright, I. M. R. (2009). Short-term outcomes of mothers and newborn infants with comorbid psychiatric disorders and drug dependency. Australian and New Zealand Journal of Psychiatry, 43 (4), 323-331.

Scopus Eid


  • 2-s2.0-67650166760

Ro Metadata Url


  • http://ro.uow.edu.au/smhpapers/1676

Number Of Pages


  • 8

Start Page


  • 323

End Page


  • 331

Volume


  • 43

Issue


  • 4

Abstract


  • Objectives: The aim of the present study was to determine the characteristics and short-term outcomes of mother–infant pairs with comorbid drug dependency and psychiatric disorders.

    Methods: A population-based retrospective chart review was carried out of 879 drug-dependent mother and infant pairs in New South Wales (NSW) and the Australian Capital Territory (ACT) who delivered between 1 January and 31 December 2004.

    Results: Psychiatric comorbidity (dual diagnosis, DD) was identified in 396 (45%) of the 879 drug-dependent women. DSM-IV depression (79%), followed by anxiety (20%), was most prevalent. DD women were more likely to use amphetamines (29% vs 18%, p < 0.05), less likely to use opiates (42% vs 51%, p < 0.05) and to have had no antenatal care (24% vs 8%, p < 0.05). They also had more previous pregnancies (4, range = 2–5 vs 3, range = 2–5, p < 0.05) and domestic violence (29% vs 14%, p < 0.05) was more common. DD infants were less likely to be admitted to a nursery (47% vs 55%, p < 0.05). Withdrawal scores were similar (maximum median Finnegan scores = 4 (interquartile range = 3–8) vs 10 (interquartile range = 7–12, p = 0.30) but fewer needed withdrawal medication (19% vs 27%, p < 0.05). Maternal psychotropic agents did not worsen the severity of neonatal withdrawal.

    Conclusions: Psychiatric comorbidity, especially depression, is common and affects almost half of drug-using mothers. Antenatal care, drug use and social outcomes are worse for DD mothers and their infants. It is recommended that all drug-using women be assessed antenatally for psychosocial disorders so that timely mental health intervention can be offered, if required.

Authors


  •   Oei, Ju Lee (external author)
  •   Abdel-Latif, Mohamed E. (external author)
  •   Craig, Fiona (external author)
  •   Kee, Aivy (external author)
  •   Austin, Marie-Paule (external author)
  •   Lui, Kei (external author)
  •   Wright, Ian M. R.

Publication Date


  • 2009

Citation


  • Oei, J., Abdel-Latif, M. E., Craig, F., Kee, A., Austin, M., Lui, K. & Wright, I. M. R. (2009). Short-term outcomes of mothers and newborn infants with comorbid psychiatric disorders and drug dependency. Australian and New Zealand Journal of Psychiatry, 43 (4), 323-331.

Scopus Eid


  • 2-s2.0-67650166760

Ro Metadata Url


  • http://ro.uow.edu.au/smhpapers/1676

Number Of Pages


  • 8

Start Page


  • 323

End Page


  • 331

Volume


  • 43

Issue


  • 4