Reinforcing biopolymer hydrogels with ionic-covalent entanglement hydrogel microspheres

Journal Article


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Abstract


  • Microscopic hydrogel spheres can be used to improve the mechanical properties of conventional hydrogels. We prepared ionic-covalent entanglement (ICE) hydrogel microspheres of calcium cross-linked gellan gum and genipin cross-linked gelatin using a water-in-oil emulsion-based processing technique. The method was optimized to produce microspheres with number average diameter 4 ± 1 µm. These ICE microspheres were used to reinforce gelatin hydrogels and improve their compressive mechanical properties. The strongest microsphere reinforced hydrogels possessed a compressive mechanical stress at failure of 0.50 ± 0.1 MPa and a compressive secant modulus of 0.18 ± 0.02 MPa.

Publication Date


  • 2014

Citation


  • Kirchmajer, D. Martin. & in het Panhuis, M. (2014). Reinforcing biopolymer hydrogels with ionic-covalent entanglement hydrogel microspheres. Journal of Applied Polymer Science, 131 (15), 1-8.

Scopus Eid


  • 2-s2.0-84900488320

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=2066&context=aiimpapers

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/1065

Has Global Citation Frequency


Number Of Pages


  • 7

Start Page


  • 1

End Page


  • 8

Volume


  • 131

Issue


  • 15

Place Of Publication


  • United States

Abstract


  • Microscopic hydrogel spheres can be used to improve the mechanical properties of conventional hydrogels. We prepared ionic-covalent entanglement (ICE) hydrogel microspheres of calcium cross-linked gellan gum and genipin cross-linked gelatin using a water-in-oil emulsion-based processing technique. The method was optimized to produce microspheres with number average diameter 4 ± 1 µm. These ICE microspheres were used to reinforce gelatin hydrogels and improve their compressive mechanical properties. The strongest microsphere reinforced hydrogels possessed a compressive mechanical stress at failure of 0.50 ± 0.1 MPa and a compressive secant modulus of 0.18 ± 0.02 MPa.

Publication Date


  • 2014

Citation


  • Kirchmajer, D. Martin. & in het Panhuis, M. (2014). Reinforcing biopolymer hydrogels with ionic-covalent entanglement hydrogel microspheres. Journal of Applied Polymer Science, 131 (15), 1-8.

Scopus Eid


  • 2-s2.0-84900488320

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=2066&context=aiimpapers

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/1065

Has Global Citation Frequency


Number Of Pages


  • 7

Start Page


  • 1

End Page


  • 8

Volume


  • 131

Issue


  • 15

Place Of Publication


  • United States