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Quantum dot-based nanoprobes for in vivo targeted imaging

Journal Article


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Abstract


  • Fluorescent semiconductor quantum dots (QDs) have attracted tremendous attention over the last decade. The superior optical properties of QDs over conventional organic dyes make them attractive labels for a wide variety of biomedical applications, whereas their potential toxicity and instability in biological environment have puzzled scientific researchers. Much research effort has been devoted to surface modification and functionalization of QDs to make them versatile probes for biomedical applications, and significant progress has been made over the last several years. This review article aims to describe the current state-of-the-art of the synthesis, modification, bioconjugation, and applications of QDs for in vivo targeted imaging. In addition, QD-based multifunctional nanoprobes are also summarized.

UOW Authors


  •   Hong, H (external author)
  •   Xu, Zhi Ping (external author)
  •   Zhu, Yian (external author)
  •   Cai, W (external author)
  •   Li, Zhen

Publication Date


  • 2013

Citation


  • Zhu, Y., Hong, H., Xu, Z. P., Li, Z. & Cai, W. (2013). Quantum dot-based nanoprobes for in vivo targeted imaging. Current Molecular Medicine, 13 (10), 1549-1567.

Scopus Eid


  • 2-s2.0-84889005600

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=1979&context=aiimpapers

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/978

Has Global Citation Frequency


Number Of Pages


  • 18

Start Page


  • 1549

End Page


  • 1567

Volume


  • 13

Issue


  • 10

Abstract


  • Fluorescent semiconductor quantum dots (QDs) have attracted tremendous attention over the last decade. The superior optical properties of QDs over conventional organic dyes make them attractive labels for a wide variety of biomedical applications, whereas their potential toxicity and instability in biological environment have puzzled scientific researchers. Much research effort has been devoted to surface modification and functionalization of QDs to make them versatile probes for biomedical applications, and significant progress has been made over the last several years. This review article aims to describe the current state-of-the-art of the synthesis, modification, bioconjugation, and applications of QDs for in vivo targeted imaging. In addition, QD-based multifunctional nanoprobes are also summarized.

UOW Authors


  •   Hong, H (external author)
  •   Xu, Zhi Ping (external author)
  •   Zhu, Yian (external author)
  •   Cai, W (external author)
  •   Li, Zhen

Publication Date


  • 2013

Citation


  • Zhu, Y., Hong, H., Xu, Z. P., Li, Z. & Cai, W. (2013). Quantum dot-based nanoprobes for in vivo targeted imaging. Current Molecular Medicine, 13 (10), 1549-1567.

Scopus Eid


  • 2-s2.0-84889005600

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=1979&context=aiimpapers

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/978

Has Global Citation Frequency


Number Of Pages


  • 18

Start Page


  • 1549

End Page


  • 1567

Volume


  • 13

Issue


  • 10