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Men who have sex with men, infectious syphilis and HIV coinfection in inner Sydney: results of enhanced surveillance

Journal Article


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Abstract


  • Background: The resurgence of infectious syphilis in men who have sex with men (MSM) has been documented worldwide; however, HIV coinfection and syphilis reinfections in MSM in inner Sydney have not been published. Methods: For all laboratory syphilis notifications assessed as a newly notified case or reinfection, a questionnaire was sent to the requesting physician seeking demographic data and disease classification. Sex of partner and HIV status were collected for all infectious syphilis notifications in men received from 1 April 2006 to March 2011. Results: From April 2001 to March 2011, 3664 new notifications were received, 2278 (62%) were classified as infectious syphilis. Infectious syphilis notifications increased 12-fold from 25 to 303 in the first and last year respectively, and almost all notifications were in men (2220, 97.5%). During April 2006 to March 2011, 1562 infectious syphilis notifications in males were received and 765 (49%) of these men were HIV-positive and 1351 (86%) reported a male sex partner. Reinfections increased over time from 17 (9%) to 56 (19%) in the last year of the study and were significantly more likely to be in HIV-positive individuals (χ2 = 140.92, degrees of freedom= 1, P = <0.001). Conclusion: Inner Sydney is experiencing an epidemic of infectious syphilis in MSM and about half of these cases are in HIV-positive patients. Reinfections are increasing and occur predominantly in HIV-positive men. Accurate surveillance information is needed to inform effective prevention programs, and community and clinician education needs to continue until a sustained reduction is achieved.

UOW Authors


  •   Botham, Susan J. (external author)
  •   Ressler, Kelly-Anne (external author)
  •   Maywood, Patrick (external author)
  •   Hope, Kirsty G. (external author)
  •   Bourne, Chris (external author)
  •   Conaty, Stephen (external author)
  •   Ferson, Mark J. (external author)
  •   Mayne, Darren

Publication Date


  • 2013

Citation


  • Botham, S. J., Ressler, K., Maywood, P., Hope, K. G., Bourne, C. P., Conaty, S. J., Ferson, M. J. & Mayne, D. J. (2013). Men who have sex with men, infectious syphilis and HIV coinfection in inner Sydney: results of enhanced surveillance. Sexual Health, 10 (4), 291-298.

Scopus Eid


  • 2-s2.0-84881148958

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=1359&context=ihmri

Ro Metadata Url


  • http://ro.uow.edu.au/ihmri/342

Has Global Citation Frequency


Number Of Pages


  • 7

Start Page


  • 291

End Page


  • 298

Volume


  • 10

Issue


  • 4

Place Of Publication


  • Australia

Abstract


  • Background: The resurgence of infectious syphilis in men who have sex with men (MSM) has been documented worldwide; however, HIV coinfection and syphilis reinfections in MSM in inner Sydney have not been published. Methods: For all laboratory syphilis notifications assessed as a newly notified case or reinfection, a questionnaire was sent to the requesting physician seeking demographic data and disease classification. Sex of partner and HIV status were collected for all infectious syphilis notifications in men received from 1 April 2006 to March 2011. Results: From April 2001 to March 2011, 3664 new notifications were received, 2278 (62%) were classified as infectious syphilis. Infectious syphilis notifications increased 12-fold from 25 to 303 in the first and last year respectively, and almost all notifications were in men (2220, 97.5%). During April 2006 to March 2011, 1562 infectious syphilis notifications in males were received and 765 (49%) of these men were HIV-positive and 1351 (86%) reported a male sex partner. Reinfections increased over time from 17 (9%) to 56 (19%) in the last year of the study and were significantly more likely to be in HIV-positive individuals (χ2 = 140.92, degrees of freedom= 1, P = <0.001). Conclusion: Inner Sydney is experiencing an epidemic of infectious syphilis in MSM and about half of these cases are in HIV-positive patients. Reinfections are increasing and occur predominantly in HIV-positive men. Accurate surveillance information is needed to inform effective prevention programs, and community and clinician education needs to continue until a sustained reduction is achieved.

UOW Authors


  •   Botham, Susan J. (external author)
  •   Ressler, Kelly-Anne (external author)
  •   Maywood, Patrick (external author)
  •   Hope, Kirsty G. (external author)
  •   Bourne, Chris (external author)
  •   Conaty, Stephen (external author)
  •   Ferson, Mark J. (external author)
  •   Mayne, Darren

Publication Date


  • 2013

Citation


  • Botham, S. J., Ressler, K., Maywood, P., Hope, K. G., Bourne, C. P., Conaty, S. J., Ferson, M. J. & Mayne, D. J. (2013). Men who have sex with men, infectious syphilis and HIV coinfection in inner Sydney: results of enhanced surveillance. Sexual Health, 10 (4), 291-298.

Scopus Eid


  • 2-s2.0-84881148958

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=1359&context=ihmri

Ro Metadata Url


  • http://ro.uow.edu.au/ihmri/342

Has Global Citation Frequency


Number Of Pages


  • 7

Start Page


  • 291

End Page


  • 298

Volume


  • 10

Issue


  • 4

Place Of Publication


  • Australia