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Organic conducting polymer-protein interactions

Journal Article


Abstract


  • In this review, we provide insight into protein

    interactions with organic conducting polymers, a class of

    “intelligent” and dynamic materials that offer unique strategies

    for controlling protein interactions as a prelude to developing a

    wide range of bioapplications. Following a general introduction

    on the importance of protein interactions, this review initially

    focuses on the areas of bioseparation and biosensor

    applications. These applications amount to an extensive body

    of work; however, we provide only a brief overview for the

    purpose of introducing palpable examples of translating the

    ability to control organic conducting polymer−protein

    interactions into practical and useful applications. Because

    organic conducting polymers are breaking new ground for

    implantable electrodes and tissue regeneration/engineering, we

    duly turn to the importance of protein interactions and role

    organic conducting polymers can play in advancing these

    applications. Lastly, for those not familiar with organic

    conducting polymers, we take a step back and examine the

    unique properties underlying their innate ability to control

    protein interactions, particularly the use of external electrical control to reversibly switch the physical surface properties. Several

    characterization techniques identified as being critical to our understanding at the macroscopic down to the single molecule level

    are also highlighted.

Publication Date


  • 2012

Citation


  • Higgins, M. J., Molino, P. J., Yue, Z. & Wallace, G. G. (2012). Organic conducting polymer-protein interactions. Chemistry of Materials, 24 (5), 828-839.

Scopus Eid


  • 2-s2.0-84858167083

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/646

Has Global Citation Frequency


Number Of Pages


  • 11

Start Page


  • 828

End Page


  • 839

Volume


  • 24

Issue


  • 5

Place Of Publication


  • United States

Abstract


  • In this review, we provide insight into protein

    interactions with organic conducting polymers, a class of

    “intelligent” and dynamic materials that offer unique strategies

    for controlling protein interactions as a prelude to developing a

    wide range of bioapplications. Following a general introduction

    on the importance of protein interactions, this review initially

    focuses on the areas of bioseparation and biosensor

    applications. These applications amount to an extensive body

    of work; however, we provide only a brief overview for the

    purpose of introducing palpable examples of translating the

    ability to control organic conducting polymer−protein

    interactions into practical and useful applications. Because

    organic conducting polymers are breaking new ground for

    implantable electrodes and tissue regeneration/engineering, we

    duly turn to the importance of protein interactions and role

    organic conducting polymers can play in advancing these

    applications. Lastly, for those not familiar with organic

    conducting polymers, we take a step back and examine the

    unique properties underlying their innate ability to control

    protein interactions, particularly the use of external electrical control to reversibly switch the physical surface properties. Several

    characterization techniques identified as being critical to our understanding at the macroscopic down to the single molecule level

    are also highlighted.

Publication Date


  • 2012

Citation


  • Higgins, M. J., Molino, P. J., Yue, Z. & Wallace, G. G. (2012). Organic conducting polymer-protein interactions. Chemistry of Materials, 24 (5), 828-839.

Scopus Eid


  • 2-s2.0-84858167083

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/646

Has Global Citation Frequency


Number Of Pages


  • 11

Start Page


  • 828

End Page


  • 839

Volume


  • 24

Issue


  • 5

Place Of Publication


  • United States