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Attention-induced deactivations in very low frequency EEG oscillations: Differential localisation according to ADHD symptom status

Journal Article


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Abstract


  • Background: The default-mode network (DMN) is characterised by coherent very low frequency (VLF) brain oscillations. The

    cognitive significance of this VLF profile remains unclear, partly because of the temporally constrained nature of the blood

    oxygen-level dependent (BOLD) signal. Previously we have identified a VLF EEG network of scalp locations that shares many

    features of the DMN. Here we explore the intracranial sources of VLF EEG and examine their overlap with the DMN in adults

    with high and low ADHD ratings.

    Methodology/Principal Findings: DC-EEG was recorded using an equidistant 66 channel electrode montage in 25 adult

    participants with high- and 25 participants with low-ratings of ADHD symptoms during a rest condition and an attention

    demanding Eriksen task. VLF EEG power was calculated in the VLF band (0.02 to 0.2 Hz) for the rest and task condition and

    compared for high and low ADHD participants. sLORETA was used to identify brain sources associated with the attentioninduced

    deactivation of VLF EEG power, and to examine these sources in relation to ADHD symptoms. There was significant

    deactivation of VLF EEG power between the rest and task condition for the whole sample. Using s-LORETA the sources of

    this deactivation were localised to medial prefrontal regions, posterior cingulate cortex/precuneus and temporal regions.

    However, deactivation sources were different for high and low ADHD groups: In the low ADHD group attention-induced VLF

    EEG deactivation was most significant in medial prefrontal regions while for the high ADHD group this deactivation was

    predominantly localised to the temporal lobes.

    Conclusions/Significance: Attention-induced VLF EEG deactivations have intracranial sources that appear to overlap with those

    of the DMN. Furthermore, these seem to be related to ADHD symptom status, with high ADHD adults failing to significantly

    deactivatemedial prefrontal regions while at the same time showing significant attenuation of VLF EEG power in temporal lobes.

UOW Authors


  •   Broyd, Samantha (external author)
  •   Helps, S (external author)
  •   Sonuga-Barke, E (external author)

Publication Date


  • 2011

Citation


  • Broyd, S., Helps, S. K. & Sonuga-Barke, E. J.S. (2011). Attention-induced deactivations in very low frequency EEG oscillations: Differential localisation according to ADHD symptom status. PLoS One, 6 (3), 1-8.

Scopus Eid


  • 2-s2.0-79952376710

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=1068&context=sspapers

Ro Metadata Url


  • http://ro.uow.edu.au/sspapers/69

Number Of Pages


  • 7

Start Page


  • 1

End Page


  • 8

Volume


  • 6

Issue


  • 3

Abstract


  • Background: The default-mode network (DMN) is characterised by coherent very low frequency (VLF) brain oscillations. The

    cognitive significance of this VLF profile remains unclear, partly because of the temporally constrained nature of the blood

    oxygen-level dependent (BOLD) signal. Previously we have identified a VLF EEG network of scalp locations that shares many

    features of the DMN. Here we explore the intracranial sources of VLF EEG and examine their overlap with the DMN in adults

    with high and low ADHD ratings.

    Methodology/Principal Findings: DC-EEG was recorded using an equidistant 66 channel electrode montage in 25 adult

    participants with high- and 25 participants with low-ratings of ADHD symptoms during a rest condition and an attention

    demanding Eriksen task. VLF EEG power was calculated in the VLF band (0.02 to 0.2 Hz) for the rest and task condition and

    compared for high and low ADHD participants. sLORETA was used to identify brain sources associated with the attentioninduced

    deactivation of VLF EEG power, and to examine these sources in relation to ADHD symptoms. There was significant

    deactivation of VLF EEG power between the rest and task condition for the whole sample. Using s-LORETA the sources of

    this deactivation were localised to medial prefrontal regions, posterior cingulate cortex/precuneus and temporal regions.

    However, deactivation sources were different for high and low ADHD groups: In the low ADHD group attention-induced VLF

    EEG deactivation was most significant in medial prefrontal regions while for the high ADHD group this deactivation was

    predominantly localised to the temporal lobes.

    Conclusions/Significance: Attention-induced VLF EEG deactivations have intracranial sources that appear to overlap with those

    of the DMN. Furthermore, these seem to be related to ADHD symptom status, with high ADHD adults failing to significantly

    deactivatemedial prefrontal regions while at the same time showing significant attenuation of VLF EEG power in temporal lobes.

UOW Authors


  •   Broyd, Samantha (external author)
  •   Helps, S (external author)
  •   Sonuga-Barke, E (external author)

Publication Date


  • 2011

Citation


  • Broyd, S., Helps, S. K. & Sonuga-Barke, E. J.S. (2011). Attention-induced deactivations in very low frequency EEG oscillations: Differential localisation according to ADHD symptom status. PLoS One, 6 (3), 1-8.

Scopus Eid


  • 2-s2.0-79952376710

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=1068&context=sspapers

Ro Metadata Url


  • http://ro.uow.edu.au/sspapers/69

Number Of Pages


  • 7

Start Page


  • 1

End Page


  • 8

Volume


  • 6

Issue


  • 3