Skip to main content

Bacterial plasminogen receptors: mediators of a multifaceted relationship

Journal Article


Download full-text (Open Access)

Abstract


  • Multiple species of bacteria are able to sequester the host zymogen plasminogen to the cell surface. Once localised to the bacterial surface, plasminogen can act as a cofactor in adhesion, or, following activation to plasmin, provide a source of potent proteolytic activity. Numerous bacterial plasminogen receptors have been identified, and the mechanisms by which they interact with plasminogen are diverse. Here we provide an overview of bacterial plasminogen receptors and discuss the diverse role bacterial plasminogen acquisition plays in the relationship between bacteria and the host.

Publication Date


  • 2012

Citation


  • Sanderson-Smith, M. L., De Oliveira, D. M. P., Ranson, M. & McArthur, J. D. (2012). Bacterial plasminogen receptors: mediators of a multifaceted relationship. Journal of Biomedicine and Biotechnology, 2012 1-14.

Scopus Eid


  • 2-s2.0-84869068939

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=8093&context=scipapers

Ro Metadata Url


  • http://ro.uow.edu.au/scipapers/4750

Has Global Citation Frequency


Number Of Pages


  • 13

Start Page


  • 1

End Page


  • 14

Volume


  • 2012

Place Of Publication


  • United States

Abstract


  • Multiple species of bacteria are able to sequester the host zymogen plasminogen to the cell surface. Once localised to the bacterial surface, plasminogen can act as a cofactor in adhesion, or, following activation to plasmin, provide a source of potent proteolytic activity. Numerous bacterial plasminogen receptors have been identified, and the mechanisms by which they interact with plasminogen are diverse. Here we provide an overview of bacterial plasminogen receptors and discuss the diverse role bacterial plasminogen acquisition plays in the relationship between bacteria and the host.

Publication Date


  • 2012

Citation


  • Sanderson-Smith, M. L., De Oliveira, D. M. P., Ranson, M. & McArthur, J. D. (2012). Bacterial plasminogen receptors: mediators of a multifaceted relationship. Journal of Biomedicine and Biotechnology, 2012 1-14.

Scopus Eid


  • 2-s2.0-84869068939

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=8093&context=scipapers

Ro Metadata Url


  • http://ro.uow.edu.au/scipapers/4750

Has Global Citation Frequency


Number Of Pages


  • 13

Start Page


  • 1

End Page


  • 14

Volume


  • 2012

Place Of Publication


  • United States