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Short-term effects of fish and fish oil consumption on total and high molecular weight adiponectin levels in overweight and obese adults

Journal Article


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Abstract


  • Objective

    Fish or fish oil consumption may increase levels of total and high molecular weight (HMW) adiponectin, a hormone associated with anti-inflammatory and insulin-sensitising effects, however it is not known if the effects of the food and supplement are the same. The aim of this study was to compare the effect of consuming fish and fish oil supplements on plasma total and HMW adiponectin concentrations in overweight human participants.

    Materials/Methods

    29 overweight and obese participants underwent a two week run-in period, followed by a four week isocaloric dietary intervention which provided 1.8g of long chain omega-3 polyunsaturated fatty acids (LC n-3 PUFA) in the form of either fish or fish oil supplements. Primary outcomes were changes in plasma total and HMW adiponectin. Secondary outcomes were changes in anthropometric variables, plasma insulin and glucose levels, and dietary intakes.

    Results

    Changes in plasma HMW adiponectin during the intervention period were significantly different between groups (p=0.009). Mean HMW adiponectin increased by 0.29μg/mL in the ‘fish’ group and decreased by 0.60μg/mL in the ‘supplement’ group. There were no significant changes in other anthropometric and biochemical variables. Dietary data suggested the ‘fish’ group significantly increased their fish (p=0.001) and dietary LC n-3 PUFA (p=0.001) consumption over the course of the study.

    Conclusions

    Short-term consumption of fish and fish oil supplements did not have the same effects on HMW adiponectin levels. The impact of fish intake on HMW adiponectin levels may not be mediated by its LC n-3 PUFA content alone.

Publication Date


  • 2013

Citation


  • Neale, E. P., Muhlhausler, B., Probst, Y. C., Batterham, M. J., Fernandez, F. & Tapsell, L. C. (2013). Short-term effects of fish and fish oil consumption on total and high molecular weight adiponectin levels in overweight and obese adults. Metabolism: clinical and experimental, 62 (5), 651-660.

Scopus Eid


  • 2-s2.0-84876669710

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=2367&context=smhpapers

Ro Metadata Url


  • http://ro.uow.edu.au/smhpapers/1349

Has Global Citation Frequency


Number Of Pages


  • 9

Start Page


  • 651

End Page


  • 660

Volume


  • 62

Issue


  • 5

Place Of Publication


  • United States

Abstract


  • Objective

    Fish or fish oil consumption may increase levels of total and high molecular weight (HMW) adiponectin, a hormone associated with anti-inflammatory and insulin-sensitising effects, however it is not known if the effects of the food and supplement are the same. The aim of this study was to compare the effect of consuming fish and fish oil supplements on plasma total and HMW adiponectin concentrations in overweight human participants.

    Materials/Methods

    29 overweight and obese participants underwent a two week run-in period, followed by a four week isocaloric dietary intervention which provided 1.8g of long chain omega-3 polyunsaturated fatty acids (LC n-3 PUFA) in the form of either fish or fish oil supplements. Primary outcomes were changes in plasma total and HMW adiponectin. Secondary outcomes were changes in anthropometric variables, plasma insulin and glucose levels, and dietary intakes.

    Results

    Changes in plasma HMW adiponectin during the intervention period were significantly different between groups (p=0.009). Mean HMW adiponectin increased by 0.29μg/mL in the ‘fish’ group and decreased by 0.60μg/mL in the ‘supplement’ group. There were no significant changes in other anthropometric and biochemical variables. Dietary data suggested the ‘fish’ group significantly increased their fish (p=0.001) and dietary LC n-3 PUFA (p=0.001) consumption over the course of the study.

    Conclusions

    Short-term consumption of fish and fish oil supplements did not have the same effects on HMW adiponectin levels. The impact of fish intake on HMW adiponectin levels may not be mediated by its LC n-3 PUFA content alone.

Publication Date


  • 2013

Citation


  • Neale, E. P., Muhlhausler, B., Probst, Y. C., Batterham, M. J., Fernandez, F. & Tapsell, L. C. (2013). Short-term effects of fish and fish oil consumption on total and high molecular weight adiponectin levels in overweight and obese adults. Metabolism: clinical and experimental, 62 (5), 651-660.

Scopus Eid


  • 2-s2.0-84876669710

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=2367&context=smhpapers

Ro Metadata Url


  • http://ro.uow.edu.au/smhpapers/1349

Has Global Citation Frequency


Number Of Pages


  • 9

Start Page


  • 651

End Page


  • 660

Volume


  • 62

Issue


  • 5

Place Of Publication


  • United States