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Continuous particle focusing in a waved microchannel using negative dc dielectrophoresis

Journal Article


Abstract


  • We present a waved microchannel for continuous focusing of microparticles and cells using

    negative direct current (dc) dielectrophoresis. The waved channel is composed of consecutive

    s-shaped curved channels in series to generate an electric field gradient required for

    the dielectrophoretic effect. When particles move electrokinetically through the channel, the

    experienced negative dielectrophoretic forces alternate directions within two adjacent

    semicircular microchannels, leading to a focused continuous-flow stream along the channel

    centerline. Both the experimentally observed and numerically simulated results of the focusing

    performance are reported, which coincide acceptably in proportion to the specified dimensions

    (i.e. inlet and outlet of the waved channel). How the applied electric field, particle size and

    medium concentration affect the performance was studied by focusing polystyrene

    microparticles of varying sizes. As an application in the field of biology, the focusing of yeast

    cells in the waved mcirochannel was tested. This waved microchannel shows a great potential

    for microflow cytometry applications and is expected to be widely used before different

    processing steps in lab-on-a-chip devices with integrated functions.

UOW Authors


  •   Li, Ming (external author)
  •   Li, Shunbo (external author)
  •   Cao, Wenbin (external author)
  •   Li, Weihua
  •   Wen, Weijia (external author)
  •   Alici, Gursel

Publication Date


  • 2012

Citation


  • Li, M., Li, S., Cao, W., Li, W., Wen, W. & Alici, G. (2012). Continuous particle focusing in a waved microchannel using negative dc dielectrophoresis. Journal of Micromechanics and Microengineering, 22 (9), 1-8.

Scopus Eid


  • 2-s2.0-84866307385

Ro Metadata Url


  • http://ro.uow.edu.au/engpapers/5123

Has Global Citation Frequency


Number Of Pages


  • 7

Start Page


  • 1

End Page


  • 8

Volume


  • 22

Issue


  • 9

Place Of Publication


  • United Kingdom

Abstract


  • We present a waved microchannel for continuous focusing of microparticles and cells using

    negative direct current (dc) dielectrophoresis. The waved channel is composed of consecutive

    s-shaped curved channels in series to generate an electric field gradient required for

    the dielectrophoretic effect. When particles move electrokinetically through the channel, the

    experienced negative dielectrophoretic forces alternate directions within two adjacent

    semicircular microchannels, leading to a focused continuous-flow stream along the channel

    centerline. Both the experimentally observed and numerically simulated results of the focusing

    performance are reported, which coincide acceptably in proportion to the specified dimensions

    (i.e. inlet and outlet of the waved channel). How the applied electric field, particle size and

    medium concentration affect the performance was studied by focusing polystyrene

    microparticles of varying sizes. As an application in the field of biology, the focusing of yeast

    cells in the waved mcirochannel was tested. This waved microchannel shows a great potential

    for microflow cytometry applications and is expected to be widely used before different

    processing steps in lab-on-a-chip devices with integrated functions.

UOW Authors


  •   Li, Ming (external author)
  •   Li, Shunbo (external author)
  •   Cao, Wenbin (external author)
  •   Li, Weihua
  •   Wen, Weijia (external author)
  •   Alici, Gursel

Publication Date


  • 2012

Citation


  • Li, M., Li, S., Cao, W., Li, W., Wen, W. & Alici, G. (2012). Continuous particle focusing in a waved microchannel using negative dc dielectrophoresis. Journal of Micromechanics and Microengineering, 22 (9), 1-8.

Scopus Eid


  • 2-s2.0-84866307385

Ro Metadata Url


  • http://ro.uow.edu.au/engpapers/5123

Has Global Citation Frequency


Number Of Pages


  • 7

Start Page


  • 1

End Page


  • 8

Volume


  • 22

Issue


  • 9

Place Of Publication


  • United Kingdom