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Comparison of assays for measuring plasma paracetamol. Possibility of calibration error needs evaluation

Journal Article


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Abstract


  • We compared two methods for estimat

    ing plasma paracetamol (Cobas paraceta

    mol assay kit (Cambridge Life Sciences, Ely)

    and AcetaSite blood acetaminophen (para

    cetamol) test (Cambridge Life Sciences))

    with a standard high performance liquid

    chromatographic method.3 We used the

    methods on 35 samples from 23 patients

    presenting between 5 and 50 hours after

    a paracetamol overdose who claimed to

    have taken a mean of 22.0 g (range 550

    (SD 13.1) g) of paracetamol alone. Samples

    were taken and stored at - 40°C, and all

    assays were performed in our laboratory.

UOW Authors


  •   Jones, Alison
  •   Jarvie, D R. (external author)
  •   Simpson, D (external author)
  •   Prescott, L F. (external author)

Publication Date


  • 1998

Citation


  • JONES, A. LINDA., Jarvie, D. R., Simpson, D. & Prescott, L. F. (1998). Comparison of assays for measuring plasma paracetamol. Possibility of calibration error needs evaluation. BMJ (Clinical research ed.), 316 (7129), 475.

Scopus Eid


  • 2-s2.0-85007753551

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=1176&context=medpapers

Ro Metadata Url


  • http://ro.uow.edu.au/medpapers/172

Start Page


  • 475

Volume


  • 316

Issue


  • 7129

Abstract


  • We compared two methods for estimat

    ing plasma paracetamol (Cobas paraceta

    mol assay kit (Cambridge Life Sciences, Ely)

    and AcetaSite blood acetaminophen (para

    cetamol) test (Cambridge Life Sciences))

    with a standard high performance liquid

    chromatographic method.3 We used the

    methods on 35 samples from 23 patients

    presenting between 5 and 50 hours after

    a paracetamol overdose who claimed to

    have taken a mean of 22.0 g (range 550

    (SD 13.1) g) of paracetamol alone. Samples

    were taken and stored at - 40°C, and all

    assays were performed in our laboratory.

UOW Authors


  •   Jones, Alison
  •   Jarvie, D R. (external author)
  •   Simpson, D (external author)
  •   Prescott, L F. (external author)

Publication Date


  • 1998

Citation


  • JONES, A. LINDA., Jarvie, D. R., Simpson, D. & Prescott, L. F. (1998). Comparison of assays for measuring plasma paracetamol. Possibility of calibration error needs evaluation. BMJ (Clinical research ed.), 316 (7129), 475.

Scopus Eid


  • 2-s2.0-85007753551

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=1176&context=medpapers

Ro Metadata Url


  • http://ro.uow.edu.au/medpapers/172

Start Page


  • 475

Volume


  • 316

Issue


  • 7129