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Molecular systems for improving gene mutation correction in muscle disease

Journal Article


Abstract


  • Targeted corrective gene conversion (TCGC)

    holds much promise as a future therapy for

    many hereditary diseases in humans, but there

    still remain significant impediments to

    effective mutation correction and it is clear

    that significant work remains to improve

    TCGC to levels where it can be considered for

    translation to the clinical setting.

Authors


  •   Kapsa, Robert M. I.
  •   Gasser, Gilles A. (external author)
  •   Razal, Joselito M. (external author)
  •   Quigley, Anita F. (external author)
  •   Joshi, Tanmaya (external author)
  •   Moulton, Simon E. (external author)
  •   Cook, Mark J. (external author)
  •   Spiccia, Leone (external author)
  •   Officer, David L.
  •   Clark, Graeme M. (external author)
  •   Wallace, Gordon G.

Publication Date


  • 2011

Citation


  • Kapsa, R., Gasser, G., Razal, J., Quigley, A., Joshi, T., Moulton, S., Cook, M. J., Spiccia, L., Officer, D., Clark, G. & Wallace, G. G. (2011). Molecular systems for improving gene mutation correction in muscle disease. Journal of Gene Medicine, 13 (7-8), 437-438.

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/738

Number Of Pages


  • 1

Start Page


  • 437

End Page


  • 438

Volume


  • 13

Issue


  • 7-8

Place Of Publication


  • Hoboken, United States

Abstract


  • Targeted corrective gene conversion (TCGC)

    holds much promise as a future therapy for

    many hereditary diseases in humans, but there

    still remain significant impediments to

    effective mutation correction and it is clear

    that significant work remains to improve

    TCGC to levels where it can be considered for

    translation to the clinical setting.

Authors


  •   Kapsa, Robert M. I.
  •   Gasser, Gilles A. (external author)
  •   Razal, Joselito M. (external author)
  •   Quigley, Anita F. (external author)
  •   Joshi, Tanmaya (external author)
  •   Moulton, Simon E. (external author)
  •   Cook, Mark J. (external author)
  •   Spiccia, Leone (external author)
  •   Officer, David L.
  •   Clark, Graeme M. (external author)
  •   Wallace, Gordon G.

Publication Date


  • 2011

Citation


  • Kapsa, R., Gasser, G., Razal, J., Quigley, A., Joshi, T., Moulton, S., Cook, M. J., Spiccia, L., Officer, D., Clark, G. & Wallace, G. G. (2011). Molecular systems for improving gene mutation correction in muscle disease. Journal of Gene Medicine, 13 (7-8), 437-438.

Ro Metadata Url


  • http://ro.uow.edu.au/aiimpapers/738

Number Of Pages


  • 1

Start Page


  • 437

End Page


  • 438

Volume


  • 13

Issue


  • 7-8

Place Of Publication


  • Hoboken, United States