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Isolation of linobiflavonoid, a novel biflavonoid from Linostoma pauciflorum Griff

Journal Article


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Abstract


  • "A novel biflavonoid, that we have named linobiflavonoid, and the known biscoumarin ether, daphnoretin, were isolated from the root extracts of Linostoma pauciflorum Griff. The structure of linobiflavonoid was determined from interpretation of its NMR spectroscopic data and from a comparison of this data with those of known biflavonoids and biflavones. The known flavones, 5,4'-dihydroxy- 7,3',5'-trimethoxyflavone and 5,4'-dihydroxy-7-methoxyflavone along with stigmasterol were isolated from the vines of the same plant. 4'-Dihydroxy-7,3'-5'-trimethoxyflavone was active against Mycobacterium tuberculosis (MIC 3.13 mu M) and KB-oral cavity cancer (IC(50) 17.41 mu M). (C) 2011 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved."

UOW Authors


  •   Navarat, Tawesin (external author)
  •   Pyne, Stephen
  •   Prawat, Uma (external author)
  •   Tuntiwachwuttikul, Pittaya (external author)

Publication Date


  • 2011

Citation


  • Navarat, T., Pyne, S. G., Prawat, U. & Tuntiwachwuttikul, P. (2011). Isolation of linobiflavonoid, a novel biflavonoid from Linostoma pauciflorum Griff. Phytochemistry Letters, 4 (3), 383-385.

Scopus Eid


  • 2-s2.0-80053329928

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=6394&context=scipapers

Ro Metadata Url


  • http://ro.uow.edu.au/scipapers/3052

Has Global Citation Frequency


Number Of Pages


  • 2

Start Page


  • 383

End Page


  • 385

Volume


  • 4

Issue


  • 3

Abstract


  • "A novel biflavonoid, that we have named linobiflavonoid, and the known biscoumarin ether, daphnoretin, were isolated from the root extracts of Linostoma pauciflorum Griff. The structure of linobiflavonoid was determined from interpretation of its NMR spectroscopic data and from a comparison of this data with those of known biflavonoids and biflavones. The known flavones, 5,4'-dihydroxy- 7,3',5'-trimethoxyflavone and 5,4'-dihydroxy-7-methoxyflavone along with stigmasterol were isolated from the vines of the same plant. 4'-Dihydroxy-7,3'-5'-trimethoxyflavone was active against Mycobacterium tuberculosis (MIC 3.13 mu M) and KB-oral cavity cancer (IC(50) 17.41 mu M). (C) 2011 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved."

UOW Authors


  •   Navarat, Tawesin (external author)
  •   Pyne, Stephen
  •   Prawat, Uma (external author)
  •   Tuntiwachwuttikul, Pittaya (external author)

Publication Date


  • 2011

Citation


  • Navarat, T., Pyne, S. G., Prawat, U. & Tuntiwachwuttikul, P. (2011). Isolation of linobiflavonoid, a novel biflavonoid from Linostoma pauciflorum Griff. Phytochemistry Letters, 4 (3), 383-385.

Scopus Eid


  • 2-s2.0-80053329928

Ro Full-text Url


  • http://ro.uow.edu.au/cgi/viewcontent.cgi?article=6394&context=scipapers

Ro Metadata Url


  • http://ro.uow.edu.au/scipapers/3052

Has Global Citation Frequency


Number Of Pages


  • 2

Start Page


  • 383

End Page


  • 385

Volume


  • 4

Issue


  • 3