Skip to main content

EEG coherence and symptom profiles of children with Attention-Deficit/Hyperactivity Disorder

Journal Article


Abstract


  • Objective: We compared EEG coherence in children with and without AD/HD, and sought to relate

    observed anomalies to AD/HD symptoms.

    Methods: Forty children with AD/HD and 40 age- and sex-matched controls had eyes-closed resting EEG

    coherence calculated for eight interhemispheric electrode pairs and eight intrahemispheric pairs (four

    within each hemisphere) in the delta, theta, alpha, beta and ‘‘40 Hz’’ gamma bands.

    Results: At short-medium inter-electrode distances, the AD/HD group had increased intrahemispheric

    coherence in delta and theta, and reduced (L > R) laterality in delta, alpha, beta and gamma. Over longer

    inter-electrode distances, the AD/HD group had reduced intrahemispheric coherence in alpha. In interhemispheric

    comparisons, the AD/HD group had reduced frontal coherence in delta, alpha and gamma,

    increased temporal theta and reduced temporal alpha coherences, and increased central/parietal/occipital

    coherence in theta. Smaller left-lateralized coherences in AD/HD correlated negatively with DSM Inattentive

    and DSM Total scores, and smaller frontal interhemispheric coherence in alpha correlated

    negatively with DSM Hyperactive/Impulsive score.

    Conclusions: The negative correlations between AD/HD coherence anomalies and symptoms suggest that

    several anomalies reflect compensatory brain function.

    Significance: Coherence differences in AD/HD may reflect anomalous frontal right-hemisphere linkages

    that help compensate functional brain anomalies in the left frontal regions in this disorder.

    2011 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd.

Authors


  •   Barry, Robert J.
  •   Clarke, Adam R.
  •   Hajos, Mihaly (external author)
  •   Mackie, Franca E. (external author)
  •   McCarthy, Rory (external author)
  •   Selikowitz, Mark (external author)

Publication Date


  • 2011

Citation


  • Barry, R. J., Clarke, A. R., Hajos, M., Dupuy, F. E., McCarthy, R. & Selikowitz, M. (2011). EEG coherence and symptom profiles of children with Attention-Deficit/Hyperactivity Disorder. Clinical Neurophysiology, 122 (7), 1327-1332.

Scopus Eid


  • 2-s2.0-79957586748

Ro Metadata Url


  • http://ro.uow.edu.au/hbspapers/2097

Number Of Pages


  • 5

Start Page


  • 1327

End Page


  • 1332

Volume


  • 122

Issue


  • 7

Abstract


  • Objective: We compared EEG coherence in children with and without AD/HD, and sought to relate

    observed anomalies to AD/HD symptoms.

    Methods: Forty children with AD/HD and 40 age- and sex-matched controls had eyes-closed resting EEG

    coherence calculated for eight interhemispheric electrode pairs and eight intrahemispheric pairs (four

    within each hemisphere) in the delta, theta, alpha, beta and ‘‘40 Hz’’ gamma bands.

    Results: At short-medium inter-electrode distances, the AD/HD group had increased intrahemispheric

    coherence in delta and theta, and reduced (L > R) laterality in delta, alpha, beta and gamma. Over longer

    inter-electrode distances, the AD/HD group had reduced intrahemispheric coherence in alpha. In interhemispheric

    comparisons, the AD/HD group had reduced frontal coherence in delta, alpha and gamma,

    increased temporal theta and reduced temporal alpha coherences, and increased central/parietal/occipital

    coherence in theta. Smaller left-lateralized coherences in AD/HD correlated negatively with DSM Inattentive

    and DSM Total scores, and smaller frontal interhemispheric coherence in alpha correlated

    negatively with DSM Hyperactive/Impulsive score.

    Conclusions: The negative correlations between AD/HD coherence anomalies and symptoms suggest that

    several anomalies reflect compensatory brain function.

    Significance: Coherence differences in AD/HD may reflect anomalous frontal right-hemisphere linkages

    that help compensate functional brain anomalies in the left frontal regions in this disorder.

    2011 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd.

Authors


  •   Barry, Robert J.
  •   Clarke, Adam R.
  •   Hajos, Mihaly (external author)
  •   Mackie, Franca E. (external author)
  •   McCarthy, Rory (external author)
  •   Selikowitz, Mark (external author)

Publication Date


  • 2011

Citation


  • Barry, R. J., Clarke, A. R., Hajos, M., Dupuy, F. E., McCarthy, R. & Selikowitz, M. (2011). EEG coherence and symptom profiles of children with Attention-Deficit/Hyperactivity Disorder. Clinical Neurophysiology, 122 (7), 1327-1332.

Scopus Eid


  • 2-s2.0-79957586748

Ro Metadata Url


  • http://ro.uow.edu.au/hbspapers/2097

Number Of Pages


  • 5

Start Page


  • 1327

End Page


  • 1332

Volume


  • 122

Issue


  • 7